Article
Immunology
Marianna Karachaliou, Irene Damianaki, Maria Moudatsaki, Katerina Margetaki, Theano Roumeliotaki, Vicky Bempi, Marina Moudatsaki, Lida Vaia Chatzi, Marina Vafeiadi, Manolis Kogevinas
Summary: The influenza vaccination uptake among children in Greece is low, especially for children with asthma and obesity. Further efforts should be made in promoting vaccination and targeting specific groups.
Article
Immunology
Behzad Naderalvojoud, Nilpa D. Shah, Jane N. Mutanga, Artur Belov, Rebecca Staiger, Jonathan H. Chen, Barbee Whitaker, Tina Hernandez-Boussard
Summary: This study characterizes influenza vaccination rates among Medicaid enrollees in the U.S. and investigates factors influencing vaccine uptake. The study found that vaccination rates increased during the COVID-19 period, with children having the highest rates and adults having the lowest rates. Factors such as gender, residency, and Medicaid-managed care affiliation influenced vaccine uptake positively, while mental health and substance abuse disorders decreased the likelihood of vaccination.
Article
Pediatrics
Andrew G. Sokolow, Amy P. Stallings, Carolyn Kercsmar, Theresa Harrington, Natalia Jimenez-Truque, Yuwei Zhu, Katherine Sokolow, M. Anthony Moody, Elizabeth P. Schlaudecker, Emmanuel B. Walter, Mary Allen Staat, Karen R. Broder, C. Buddy Creech
Summary: This study found that among children with asthma aged 5 to 17 years, LAIV4 was not associated with an increased frequency of asthma exacerbations or asthma-related symptoms compared to IIV4. There were no significant differences in asthma symptoms or lung function changes within 14 days post-vaccination between the two groups.
Article
Immunology
Walid Al-Qerem, Anan Jarab, Alaa Hammad, Fawaz Alasmari, Jonathan Ling, Enas Al-Zayadneh, Montaha Al-Iede, Badi'ah Alazab, Leen Hajeer
Summary: This study investigated the knowledge, attitudes, and practices of parents of asthmatic children towards influenza vaccination. The results showed that 60.4% of asthmatic children had never received a flu vaccine, with reasons including perceived lack of necessity and forgetfulness. The study emphasized the importance of raising awareness among parents of asthmatic children about the importance of vaccination.
Article
Health Policy & Services
Kelley R. Davis, Sharon L. Norman, Bradley G. Olson, Shaban Demirel, Asma A. Taha
Summary: This quality improvement project aimed to evaluate the impact of an educational intervention to improve the quality of providers' recommendations and subsequent vaccination rates. The results showed that the quality of vaccine recommendations was improved after the intervention, but the vaccination rates did not increase. The study found that providers' delivery style is important for increasing vaccination rates.
JOURNAL OF PEDIATRIC HEALTH CARE
(2022)
Article
Immunology
William A. Fisher, Vladimir Gilca, Michelle Murti, Alison Orth, Hartley Garfield, Paul Roumeliotis, Emmanouil Rampakakis, Vivien Brown, John Yaremko, Paul Van Buynder, Constantina Boikos, James A. Mansi
Summary: This study aims to understand how the funding status influences parental perceptions of approved but unfunded vaccines and their intentions to vaccinate. The results show that the funding status strongly influences parents' beliefs about the necessity, safety, and efficacy of vaccination.
Article
Multidisciplinary Sciences
Steph Wraith, Angel Balmaseda, Fausto Andres Bustos Carrillo, Guillermina Kuan, John Huddleston, John Kubale, Roger Lopez, Sergio Ojeda, Amy Schiller, Brenda Lopez, Nery Sanchez, Richard Webby, Martha Nelson, Eva Harris, Aubree Gordon
Summary: This study examines the effects of natural influenza virus infection on subsequent infection with the same influenza virus subtype/lineage, using data from a pediatric cohort in Nicaragua. The results show that individuals infected with one subtype or lineage of influenza virus have significantly lower odds of homologous reinfection for the following one to two years, but this protection wanes after two years.
NATURE COMMUNICATIONS
(2022)
Article
Immunology
Christopher A. Czaja, Myles G. Cockburn, Kathryn Colborn, Lisa Miller, Deborah S. K. Thomas, Rachel K. Herlihy, Nisha Alden, Eric A. F. Simoes
Summary: The study found that neighborhoods in Denver with higher rates of adult hospitalizations due to laboratory-confirmed influenza had lower coverage of influenza vaccine among adults. Overall vaccine coverage was low, and hospitalization rates were associated with demographic and socioeconomic characteristics. Active immunization strategies in at-risk neighborhoods may be necessary to address disparities in influenza hospitalization rates.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Hui Chen, Junqiu Wang, Yunsong Liu, Ivy Quek Ee Ling, Chih Chuan Shih, Dafei Wu, Zhiyan Fu, Raphael Tze Chuen Lee, Miao Xu, Vincent T. Chow, Sebastian Maurer-Stroh, Da Zhou, Jianjun Liu, Weiwei Zhai
Summary: This study aims to develop a computational tool for selecting the best candidate vaccine virus (CVV) based on the negative correlation between egg passage adaptation and vaccine effectiveness (VE). They characterized the pattern of sequence evolution driven by egg passage adaptation and developed a new metric known as the adaptive distance (AD) which measures the overall strength of egg passage adaptation. They found that AD is negatively correlated with influenza H3N2 vaccine effectiveness (VE) and developed a computational package called MADE to measure the adaptive distance and predict vaccine effectiveness.
Article
Immunology
Ursula C. Patel, Thomas Schultz, Justin Schmidt
Summary: The study aimed to determine the association between receiving the COVID-19 vaccination and subsequent acceptance of the influenza vaccination in a Veteran population. The results showed that individuals who received the COVID-19 vaccination had significantly higher odds of receiving the influenza vaccination, indicating that COVID-19 vaccination may increase willingness to receive the influenza vaccine.
Article
Immunology
Kailey Hughes, Donald B. Middleton, Mary Patricia Nowalk, Goundappa K. Balasubramani, Emily T. Martin, Manjusha Gaglani, H. Keipp Talbot, Manish M. Patel, Jill M. Ferdinands, Richard K. Zimmerman, Fernanda P. Silveira
Summary: This study evaluated the vaccine effectiveness against influenza hospitalization among immunocompromised adults during the 2017-2018 influenza season. The results showed that while immunocompromised adults had a higher vaccination rate, their protection against influenza was lower, with a vaccine effectiveness of 33% in the overall adult population. Further research is needed to assess vaccine effectiveness among different immunocompromising conditions and explore ways to improve effectiveness for immunocompromised individuals.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Elizabeth Marlowe, Sarah Pranikoff, Briana Borsheim, Kiarash Salafian, Elizabeth E. Halvorson, David E. Kram
Summary: An altruism-tailored educational intervention significantly improved parental attitudes and vaccine uptake in vaccine-hesitant parents. By highlighting the altruistic benefits of accepting the seasonal influenza vaccine to protect pediatric cancer patients, the intervention reduced vaccine hesitancy and improved attitudes towards childhood influenza vaccine.
Article
Public, Environmental & Occupational Health
Anushay Mistry, Boaz Odwar, Fredrick Olewe, Jonathan Kurtis, Ann M. Moormann, John Michael Ong'echa
Summary: This study assessed factors affecting participant retention through qualitative surveys. The results showed overall satisfaction among the participants, but concerns were raised regarding the amount of venous blood samples and associated risks. Future studies will address these concerns to improve study retention.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2022)
Article
Medicine, General & Internal
Yesim Ozdemir Atikel, Sevcan A. Bakkaloglu, Fabio Paglialonga, Constantinos J. Stefanidis, Varvara Askiti, Enrico Vidal, Gema Ariceta, Engin Melek, Enrico Verrina, Nikoleta Printza, Karel Vondrak, Aleksandra Zurowska, Ilona Zagozdzon, Mesiha Ekim, Elif Nursel Ozmert, Stephanie Dufek, Augustina Jankauskiene, Claus Peter Schmitt, Eszter Levai, Johan Vande Walle, Nur Canpolat, Tuula Holtta, Michel Fischbach, Ariane Zaloszyc, Guenter Klaus, Christoph Aufricht, Rukshana Shroff, Alberto Edefonti
Summary: Despite being highly recommended, vaccination rates for influenza and pneumococcal vaccines in pediatric dialysis patients were lower than expected. Pneumococcal vaccination rates were higher in peritoneal dialysis patients compared to those on hemodialysis. The efficacy of influenza and pneumococcal vaccines was demonstrated by the low infection rates.
TURKISH JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Immunology
Constantina Boikos, Lauren Fischer, Dan O'Brien, Joe Vasey, Gregg C. Sylvester, James A. Mansi
Summary: This study estimated the relative vaccine effectiveness (rVE) of cell-propagated inactivated quadrivalent influenza vaccine (ccIIV4) versus egg-derived inactivated quadrivalent influenza vaccine (eIIV4) in preventing influenza-related medical encounters in the 2018-2019 US season. The results showed a statistically significantly greater reduction in influenza-related medical encounters in individuals vaccinated with ccIIV4 compared to eIIV4, supporting ccIIV4 as a potentially more effective public health measure against influenza.
CLINICAL INFECTIOUS DISEASES
(2021)
