Article
Medicine, General & Internal
Afshin Taheriazam, Amin Saeidinia
Summary: This study aimed to evaluate the outcomes of patients who underwent 2-staged total hip arthroplasty after a course of antibiotic therapy. The results showed a success rate of 92.1% following two-stage revision and antibiotic treatment, compared to a success rate of 78.4% after the initial surgery and antibiotic therapy.
Article
Cell & Tissue Engineering
E. Lenguerrand, M. R. Whitehouse, A. D. Beswick, S. K. Kunutsor, J. C. J. Webb, S. Mehendale, M. Porter, A. W. Blom
Summary: This study compared the risks of re-revision and mortality between two-stage and single-stage revision surgeries in patients with infected primary hip arthroplasty. The results showed that two-stage revision had a lower risk of unplanned re-revision, especially in the early postoperative period. However, single-stage revision had a lower overall number of revision procedures and comparable mortality rates.
BONE & JOINT RESEARCH
(2023)
Article
Orthopedics
Jacob M. Wilson, Hilal Maradit-Kremers, Matthew P. Abdel, Daniel J. Berry, Tad M. Mabry, Mark W. Pagnano, Kevin I. Perry, Rafael J. Sierra, Michael J. Taunton, Robert T. Trousdale, David G. Lewallen
Summary: This study evaluates the survival of several contemporary acetabular designs following revision total hip arthroplasty. The results show that contemporary acetabular components have significantly improved survivorship, with a low risk of revision at 10-year follow-up, especially with highly porous designs.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Orthopedics
Hope E. Skibicki, Zachary D. Post, Andrew B. Kay, Miranda M. Czymek, Alvin C. Ong, Fabio R. Orozco, Danielle Y. Ponzio
Summary: This study compared the outcomes of patients undergoing revision THA with different types of femoral stems. The results showed that there were no significant differences in clinical and radiographic outcomes, complications, stem subsidence, leg length discrepancy, and HOOS Jr score between the two groups.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Rosa S. Valtanen, Katherine L. Hwang, Derek F. Amanatullah, James I. Huddleston, William J. Maloney, Stuart B. Goodman
Summary: This study retrospectively analyzed long-term follow-up data of patients who underwent revision total hip arthroplasty (THA) using a cementless modular stem. The results demonstrated long-term clinical success and safety of the cementless modular revision stem for complex revision operations.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Medicine, General & Internal
Beau J. Kildow, Bryan D. Springer, Timothy S. Brown, Elizabeth Lyden, Thomas K. Fehring, Kevin L. Garvin
Summary: This study evaluated the long-term outcomes of two-stage exchange hip arthroplasty for chronic periprosthetic joint infection. The technique resulted in a relatively high infection eradication rate, but the mortality rate was alarmingly high, with antibiotic resistant organisms being the highest risk factor for failure.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Infectious Diseases
Moritz Mederake, Ulf Krister Hofmann, Bernd Fink
Summary: The choice of custom-made spacers in the interim phase of two-stage revision hip arthroplasty is crucial for surgical outcomes. The new technique demonstrated a high reinfect-free rate and low spacer-related complication rate, showing superiority over conventional concepts. Further research is needed to confirm the clinical benefits of this procedure.
Article
Orthopedics
M. J. Petrie, S. Panchani, M. Al-Einzy, D. Partridge, T. P. Harrison, I. Stockley
Summary: This study retrospectively analyzed the success rate of aggressive surgical debridement with high local concentration of targeted antibiotics in the management of periprosthetic joint infection after total hip arthroplasty. The results showed that this method achieved a high success rate without the need for prolonged systemic antibiotics, which can contribute to responsible antibiotic stewardship and reduced hospital costs.
BONE & JOINT JOURNAL
(2023)
Article
Orthopedics
Mumingjiang Yishake, Lan Tang, Xi Chen, Yuejian Wang, Rongxin He
Summary: The findings suggest that partial two-stage exchange (PTE) could be a viable option for select patients with infected total hip arthroplasty (THA), providing satisfactory infection control rate and comparable clinical outcomes to total two-stage exchange, but with less harm.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Martin Lindberg-Larsen, Anders Odgaard, Charlotte Fredborg, Henrik Morville Schroder
Summary: The study aims to compare the outcomes of one-stage versus two-stage revision procedures for infected knee arthroplasty, focusing on differences in functional status, quality of life, complications, and mortality. It is a pragmatic, multi-center, randomized, non-inferiority trial with 96 prospective patients. Follow-up will include PROM-questionnaires and clinical controls up to 10 years.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Matthieu Mangin, Zouhair Aouzal, Gregoire Leclerc, Anne Pauline Sergent, Kevin Bouiller, Isabelle Patry, Patrick Garbuio
Summary: In septic total hip arthroplasty revisions, using a primary cementless stem as the first-line implant can achieve similar results in terms of infection resolution and stem integration compared to a stem cemented with antibiotics. Age greater than 80 years is a risk factor for failed infection cure during septic THAR.
ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH
(2023)
Article
Cell & Tissue Engineering
E. Lenguerrand, M. R. Whitehouse, S. K. Kunutsor, A. D. Beswick, R. P. Baker, O. Rolfson, M. R. Reed, A. W. Blom
Summary: For patients with infected primary knee arthroplasty, the risks of re-revision and mortality were similar between two-stage and single-stage revision surgeries. However, the single-stage group required fewer overall revisions, with lower or comparable mortality at specific postoperative periods.
BONE & JOINT RESEARCH
(2022)
Article
Infectious Diseases
Moritz Mederake, Ulf K. Hofmann, Sebastian Benda, Philipp Schuster, Bernd Fink
Summary: The diagnostic value of C-reactive protein (CRP) and the serum white blood cell (WBC) count for decision making during septic two-stage revision surgery of hip arthroplasty is still uncertain. This study compared these values between stages and found a significant decrease within stages but no significant difference between groups. The diagnostic value of these parameters was found to be poor.
Article
Orthopedics
Matthew J. Grosso, Elie Kozaily, Giorgio Cacciola, Javad Parvizi
Summary: This study found that prolonged time to reimplantation in 2-stage exchange arthroplasty for prosthetic hip infections is associated with high rates of acetabular and femoral bone loss, as well as increased complexity of reimplantation.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Health Care Sciences & Services
Miguel Moreno-Romero, Alejandro Ordas-Bayon, Alejandro Gomez-Rice, Miguel A. A. Ortega, Basilio J. De La Torre J. de la Torre Escuredo
Summary: Partial two-stage reconstruction is a promising technique for the treatment of chronic periprosthetic joint infection in patients with a well-fixed stem and complex re-revision acetabular procedures. Further prospective studies and prolonged follow-ups are required to confirm our results.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Orthopedics
Michael Schlumberger, Damian Oremek, Moritz Brielmaier, Uli Buntenbroich, Philipp Schuster, Bernd Fink
Summary: The study evaluated the outcomes of medial unicondylar knee arthroplasty (UKA) after failed high tibial osteotomy (HTO) for medial knee osteoarthritis, finding a 93.0% survival rate among patients followed for an average of 4.3 years. Complications included excessive valgus alignment and tibial loosening with femoropatellar degeneration. Overall, good-to-excellent results were achieved in most cases, with improvement in knee function and quality of life observed in the majority of patients.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2021)
Article
Orthopedics
B. Fink, D. Stefanou
OPERATIVE ORTHOPADIE UND TRAUMATOLOGIE
(2020)
Article
Orthopedics
Bernd Fink, Michael Schlumberger
BMC MUSCULOSKELETAL DISORDERS
(2020)
Article
Orthopedics
Moritz Mederake, Ulf Krister Hofmann, Bernd Fink
Summary: The study found that synovial biopsy has a high diagnostic value in diagnosing low-grade PJI of the shoulder, with a sensitivity of 90% and a specificity of 83%. This highlights the importance of conducting synovial biopsy in diagnosing PJI prior to complex revision surgeries.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2022)
Article
Infectious Diseases
Bernd Fink, Marius Hoyka, Elke Weissbarth, Philipp Schuster, Irina Berger
Summary: This study demonstrated that the graphical LMNE matrices can enhance the diagnostic value of automated leucocyte counting in the diagnosis of periprosthetic joint infections, allowing for differentiation between real infections and false positive results from wear particles. Additionally, the correlation between the LMNE types and histological classifications suggests a promising approach to improve the accuracy of diagnosing PJI.
Article
Infectious Diseases
Moritz Mederake, Ulf Krister Hofmann, Bernd Fink
Summary: The choice of custom-made spacers in the interim phase of two-stage revision hip arthroplasty is crucial for surgical outcomes. The new technique demonstrated a high reinfect-free rate and low spacer-related complication rate, showing superiority over conventional concepts. Further research is needed to confirm the clinical benefits of this procedure.
Editorial Material
Infectious Diseases
Konstantinos Anagnostakos, Bernd Fink
Article
Orthopedics
Bernd Fink, Mohamed Morgan, Philipp Schuster
Summary: This study compared the effectiveness of two different types of femoral stems in the reconstruction of individual hip anatomy. The results showed that the stem designed with three different femoral neck-shaft angles and a constant femoral neck length demonstrated better reconstruction of anatomical parameters compared to the standard anatomical stem.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Infectious Diseases
Moritz Mederake, Ulf K. Hofmann, Sebastian Benda, Philipp Schuster, Bernd Fink
Summary: The diagnostic value of C-reactive protein (CRP) and the serum white blood cell (WBC) count for decision making during septic two-stage revision surgery of hip arthroplasty is still uncertain. This study compared these values between stages and found a significant decrease within stages but no significant difference between groups. The diagnostic value of these parameters was found to be poor.
Article
Infectious Diseases
Bernd Fink, Marius Hoyka, Elke Weissbarth, Philipp Schuster, Irina Berger
Summary: This study evaluates the value of a new graphic representation of cell count data of synovial fluid in the diagnosis of acute periprosthetic joint infection (PJI). The results show that the graphic representation method has good sensitivity and specificity, effectively distinguishing between infection and non-infection types.
Article
Infectious Diseases
Sebastian Benda, Moritz Mederake, Philipp Schuster, Bernd Fink
Summary: This study aimed to evaluate the diagnostic value of CRP and WBC count as well as their course over 14 days postoperatively in indicating whether periprosthetic joint infection (PJI) is controlled or not during two-stage revision surgery of knee arthroplasty. The results showed that the values of CRP and WBC counts decreased significantly after the first stage of the surgery, but there was no significant difference between groups with and without reinfection. The AUC values indicated poor diagnostic value for the calculated parameters.
Article
Infectious Diseases
Lara Krueger, Andre Strahl, Leon-Gordian Koepke, Bernd Fink, Frank Timo Beil, Jan Hubert
Summary: This study evaluated the use of intraoperative cell salvage (ICS) during reimplantation of hip arthroplasties. Positive intraoperative cultures were found in 13 cases, but no significant correlation was found between the detection of positive cultures and the occurrence of complications. The use of ICS during reimplantation was considered to be indicated in terms of patient blood management, but further studies are needed for septic revision arthroplasty.
Article
Infectious Diseases
Florian Hubert Sax, Bernd Fink
Summary: The incidence of bacterial synovitis during knee endoprosthesis surgery is rare (0.12%). To reduce the risk of infection, total synovectomy, the use of bone cement with two antibiotics, and immediate systemic antibiotic therapy are effective.
Article
Orthopedics
Moritz Mederake, Ulf Krister Hofmann, Bernd Fink
Summary: This study evaluated the clinical results of endofemoral and transfemoral spacer procedures in septic two-stage revision surgery. The first clinical results were promising, with a reinfection-free rate of 90% after a median follow-up of 50 months. There were no statistical differences in complications or clinical and infectiological outcomes between the endo- and transfemoral procedures.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Orthopedics
Bernd Fink, Michael Schlumberger, Julian Beyersdorff, Philipp Schuster
JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
(2020)