Article
Health Care Sciences & Services
Neculai Onica, Cezara Andreea Onica, Elena-Raluca Baciu, Roxana-Ionela Vasluianu, Mihai Ciofu, Mihail Balan, Gabriela Luminita Geletu
Summary: The study reported a case of dental implant failure with significant bone loss and described the use of reconstructive surgical techniques for treatment. A 58-year-old man with a history of implant surgery and mandibular implant failure was presented. Cone beam computed tomography (CBCT) and intraoral scans were used to collect data, which were exported into Exoplan software to obtain a standard tessellation file. A customized mandible mesh design was created using DentalCAD 3.0 Galway software. The method involved bone reconstruction and the application of a custom titanium mesh based on guided bone regeneration, using a bone mix obtained from a combination of xenograft, allograft, and autograft. Titanium meshes were fixed to the bone with self-drilling screws and covered with a resorbable membrane. An impression was recorded immediately after surgery, and the patient received a milled polymethyl methacrylate interim denture the next day. According to the case study, the custom-made implant can be considered a temporary solution, allowing for guided bone regeneration to take place.
Article
Chemistry, Physical
Fabrizio Bambini, Giulia Orilisi, Alessandro Quaranta, Lucia Meme
Summary: This study validated a mathematical rule based on soft tissues thickness for choosing the correct implant position to prevent marginal bone loss and bacterial colonization. Implants inserted according to this rule in the Biological Oriented Immediate Loading protocol showed 100% survival rate after 5 years with minimal marginal bone loss. The use of Multi Unit Abutment also contributed to a stable biological seal and successful healing of implants.
Article
Chemistry, Multidisciplinary
Giuseppe Pantaleo, Alfonso Acerra, Francesco Giordano, Francesco D'Ambrosio, Michele Langone, Mario Caggiano
Summary: This study evaluated the clinical outcome of immediately loaded cross-arch prostheses supported by four-to-five immediately placed implants in edentulous jaws 10 years after loading. The research found that this therapeutic option is viable if robust prostheses are made.
APPLIED SCIENCES-BASEL
(2022)
Article
Medicine, General & Internal
Jimmy Londono, Todd R. Schoenbaum, Alma Veronica Varilla Ortiz, Guillermo Franco-Romero, Vanessa Villalobos, Paolo Carosi, Eitan Mijiritsky, Alessandro Pozzi
Summary: The study aimed to evaluate intra-arch mandibular dimensional changes during mouth opening using CBCT. Fifteen patients were enrolled in the study for pre- and post-CBCT assessment. CBCTs were taken with specific settings and measurements were made using radiographic markers. The results showed significant tightening and shortening of the mandible in the maximum opening position. These mandibular dimensional changes should be considered in treatment planning to avoid complications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Dentistry, Oral Surgery & Medicine
Xinke Jiang, Wenjie Zhou, Yiqun Wu, Feng Wang
Summary: Overall, the meta-analysis did not show significant differences in implant survival rate or marginal bone loss between immediately loaded implants and conventionally loaded implants. Immediate loaded implants had a high cumulative survival rate of 95.53% and a mean marginal bone loss of 1.19 mm.
INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
(2021)
Article
Medicine, General & Internal
Eugenio Velasco-Ortega, Laura Carretero-Barrado, Jesus Moreno-Munoz, Ivan Ortiz-Garcia, Enrique Nunez-Marquez, Jose Luis Rondon-Romero, Jose Lopez-Lopez, Alvaro Jimenez-Guerra, Loreto Monsalve-Guil
Summary: This study reports the outcomes of immediate loading of implants with fixed rehabilitations in edentulous geriatric patients. The results show that this treatment protocol is clinically successful, but with a high prevalence of peri-implant diseases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Dentistry, Oral Surgery & Medicine
G. Zhao, Y. Zhou, S. Shi, X. Liu, S. Zhang, Y. Song
Summary: This study compared the clinical outcomes of immediate and non-immediate loading in single-implant restorations. The results showed no significant difference in any of the outcomes of interest between the two loading methods. Immediate loading can yield predictable long-term clinical outcomes if appropriate patient selection is made.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Edmara T. P. Bergamo, Tiago M. C. Bastos, Adolfo C. O. Lopes, Everardo N. S. de Araujo Junior, Paulo G. Coelho, Ernesto B. Benalcazar Jalkh, Abbas Zahoui, Estevam A. Bonfante
Summary: The study characterized the physicochemical and mechanical properties of a milled fiber-reinforced composite for implant-supported fixed dental prostheses. Results showed that FDPs fabricated with milled epoxy resin matrix reinforced with glass fibers demonstrated high probability of survival at 300N load, indicating good fatigue performance.
Article
Dentistry, Oral Surgery & Medicine
Araceli Diez-Fraile, Lieven Barbier, Johan Abeloos
Summary: This study evaluated the long-term outcomes of full-arch rehabilitation using immediate dental implant placement and continuous functional loading with full-fixed dental prostheses. The results showed that this method was highly successful for reconstruction of atrophied maxillae, but with significant individual variations.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Qingxia Yang, Xiaoxu Guan, Baixiang Wang, Denghui Zhang, Jingyao Bai, Xiaoting Zhang, Yi Zhou
Summary: The aim of this study was to evaluate the implant survival rate, MBL, and associated risk factors of all-on-4 (5 or 6) prostheses using CBCT. The results showed high implant and prosthesis survival rates and low MBL, indicating the predictability of the all-on-4 (5 or 6) concept. Risk factors for MBL included smoking, mandible implant site, systemic disease, bruxism, female sex, immediate implant, tilted implant, and cantilever length.
JOURNAL OF PROSTHETIC DENTISTRY
(2023)
Article
Chemistry, Physical
Frank A. Spitznagel, Estevam A. Bonfante, Tiago M. B. Campos, Maximilian A. Vollmer, Johannes Boldt, Sam Doerken, Petra C. Gierthmuehlen
Summary: The study evaluated the failure-load and survival-rate of screw-retained monolithic and bi-layered crowns bonded to titanium-bases before and after mouth-motion fatigue. It was found that porcelain-fused-to-zirconia crowns showed higher failure rate under fatigue compared to monolithic LDS crowns, indicating the latter's higher reliability as an all-ceramic material for screw-retained posterior hybrid-abutment-crowns.
Article
Dentistry, Oral Surgery & Medicine
Danny Hadaya, Joan Pi-Anfruns, Benjamin Bellon, Benjamin E. Pippenger, Tara L. Aghaloo
Summary: In this short-term study, immediately loaded fully tapered implants obtained high survival with similar osseointegration ability as apically tapered implants when placed in healed sites and fresh extraction sockets.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Geninho Thome, Waleska Caldas, Sergio Rocha Bernardes, Carolina Accorsi Cartelli, Ana Helena Pereira Gracher, Larissa Carvalho Trojan
Summary: Comparing implant and prosthesis survival rates between full-arch immediate prostheses supported by four hydrophilic implants with bicortical anchorage and by five or six hydrophilic implants without bicortical anchorage, it was found that there were no significant differences in survival rates, but bicortical anchorage can improve the primary stability of implants.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Environmental Sciences
Eugenio Velasco-Ortega, Joao Luis Cracel-Lopes, Nuno Matos-Garrido, Alvaro Jimenez-Guerra, Ivan Ortiz-Garcia, Jesus Moreno-Munoz, Enrique Nunez-Marquez, Jose Luis Rondon-Romero, Jose Lopez-Lopez, Loreto Monsalve-Guil
Summary: This study evaluated the clinical outcomes of immediate functional loading of implants with fully fixed rehabilitations in compromised periodontal patients. The results showed that this treatment approach was predictable, with high implant survival rate and stable restorations.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Engineering, Multidisciplinary
Tugba Aydin, Ismail Hakki Korkmaz, Ahmet Bedreddin Sahin, Irfan Kaymaz
Summary: This study used three-dimensional finite element analysis (FEA) to investigate the effect of apical cortical bone anchorage on the stress distribution, strain distribution, and micromotion of subcrestally placed dental implants. The results showed that providing apical cortical anchorage reduced stress and strain in the trabecular bone and reduced micromotion at the implant-bone interface.
ENGINEERING SCIENCE AND TECHNOLOGY-AN INTERNATIONAL JOURNAL-JESTECH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Seiya Yamazaki, Chihiro Masaki, Tomotaka Nodai, Shintaro Tsuka, Akiko Tamura, Taro Mukaibo, Yusuke Kondo, Kentaro Ono, Ryuji Hosokawa
JOURNAL OF PROSTHODONTIC RESEARCH
(2020)
Article
Dentistry, Oral Surgery & Medicine
Yusuke Hori, Yusuke Kondo, Tomotaka Nodai, Chihiro Masaki, Kentaro Ono, Ryuji Hosokawa
Summary: The study found that while xerostomia itself did not induce bone resorption around implants, it significantly enhanced bone resorption caused by silk ligatures. Histological analysis and real-time PCR showed that xerostomia induced inflammation and osteoclastogenesis around implants with silk ligatures, as well as altered the microbiota on the plaque around implants. Xerostomia was concluded to accelerate mucosal inflammation and osteoclastogenesis, leading to aggravated bone resorption around implants.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Multidisciplinary Sciences
Ahmed Monir, Taro Mukaibo, Abdel Basit M. Abd El-Aal, Tomotaka Nodai, Takashi Munemasa, Yusuke Kondo, Chihiro Masaki, Mahasen A. El-Shair, Kou Matsuo, Ryuji Hosokawa
Summary: The study evaluated the use of beta-tricalcium phosphate (β-TCP) scaffold loaded with high mobility group box-1 protein (HMGB-1) for critical-sized bone defects in rabbits, showing that HMGB-1 could promote new bone growth and potentially serve as an effective alternative for bone regeneration.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Daisei Iwamoto, Chihiro Masaki, Yo Shibata, Chie Watanabe, Tomotaka Nodai, Takashi Munemasa, Taro Mukaibo, Yusuke Kondo, Ryuji Hosokawa
Summary: Vitamin K2, especially MK-7, inhibits bone loss in postmenopausal women. In a rat model, MK-7 administration helps in the recovery of bone microstructure and mechanical properties.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Gastroenterology & Hepatology
Gaspar Pena-Munzenmayer, Yusuke Kondo, Constanza Salinas, Jose Sarmiento, Sebastian Brauchi, Marcelo A. Catalan
Summary: This study revealed that Ae4 exchanger activity in secretory salivary gland acinar cells is enhanced upon b-adrenergic receptor stimulation, which can be blocked by H89. Protein sequence analysis identified S173 and S273 as potential targets of cAMP-dependent PKA. Experiments on CHO-K1 cells expressing S173A and S273A mutants showed that S173A, but not S273A, is not activated by PKA.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
M. Yamada, C. Masaki, T. Mukaibo, T. Munemasa, T. Nodai, Y. Kondo, R. Hosokawa
Summary: Mucin in saliva plays a critical role in hydration and lubrication of the oral mucosa. The effects of age on salivary gland function and rheological properties of saliva are not fully understood.
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Masahiko Nakamura, Yusuke Kondo, Tetsuji Nakamoto, Fumiko Nakagawa Aonuma, Tomotaka Nodai, Takashi Munemasa, Taro Mukaibo, Chihiro Masaki, Ryuji Hosokawa
Summary: The purpose of this study was to investigate serum undercarboxylated osteocalcin (ucOC) levels in partially edentulous patients scheduled to receive implant treatment and determine the association between ucOC levels, vegetable intake, vitamin K, dietary fiber intake, and functional tooth number in the posterior region (p-FTN). The study found that more than one-third of patients showed abnormally high ucOC levels and that p-FTN was negatively associated with ucOC levels.
INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yusuke Kondo, Chihiro Masaki, Taro Mukaibo, Haruka Takesue Yano, Masanori Iwasaki, Ryuji Hosokawa
Summary: This study evaluated the long-term clinical outcomes and risk factors of immediate-loading implant (ILI) treatment for fully edentulous maxillae. The results showed that ILI treatment for completely edentulous maxillae had viable long-term clinical outcomes, with male patients, shorter implant length, and narrow implant diameter negatively affecting implant survival.
INTERNATIONAL JOURNAL OF ORAL & MAXILLOFACIAL IMPLANTS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Sotaro Yamashita, Yusuke Kondo, Chie Watanabe, Tomotaka Nodai, Takashi Munemasa, Taro Mukaibo, Chihiro Masaki, Yo Shibata, Ryuji Hosokawa
Summary: The aim of this study is to investigate the effects of chronic kidney disease (CKD) on the structural and mechanical properties of the maxillary and mandibular cortical bone. Histological analyses, micro-computed tomography (CT), bone mineral density (BMD) measurements, and nanoindentation tests were used to assess CKD-induced alterations. Results showed that CKD increased the number of osteoclasts and decreased the number of osteocytes in the maxilla. CKD also caused an increase in void volume/cortical volume (%) in the maxilla and decreased BMD. Furthermore, the elastic-plastic transition point and loss modulus in the maxilla were lower in the CKD group, indicating increased micro fragility.
JOURNAL OF PROSTHODONTIC RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Sirapat Thongpoung, Chihiro Masaki, Tomotaka Nodai, Takashi Munemasa, Taro Mukaibo, Yusuke Kondo, Ryuji Hosokawa
Summary: This study used strain gauges to measure the mandibular deformation during mouth opening in edentulous patients treated with an implant-supported fixed prosthesis. The results showed that the reduction in arch width during mouth opening was higher in the molar region compared to the premolar region, and the mandibular symphyseal bone had a greater impact on the overall deformation due to its height and width ratio. The study also introduced the mandibular deformation index (MDI) as a predictor of mandibular bone deformation rate.
JOURNAL OF PROSTHODONTIC RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Tomohito Nakagawa, Shintaro Tsuka, Fumiko Aonuma, Tomotaka Nodai, Takashi Munemasa, Akiko Tamura, Taro Mukaibo, Yusuke Kondo, Chihiro Masaki, Ryuji Hosokawa
Summary: This study investigated the effect of glucose metabolism on bone healing after tooth extraction in an osteoporosis rat model administered zoledronic acid (ZA) and dexamethasonc (DX). The results showed that insulin or metformin treatment improved healing in the tooth extraction socket and reduced osteonecrosis area. In contrast, ZA and DX administration inhibited bone remodeling and induced bisphosphonate-related osteonecrosis of the jaw-like lesions.
JOURNAL OF PROSTHODONTIC RESEARCH
(2021)