Article
Dentistry, Oral Surgery & Medicine
Thomas Starch-Jensen, Soren Schou, Hendrik Terheyden, Niels Henrik Bruun, Hanna Aludden
Summary: This study tested the hypothesis of no difference in bone regeneration after maxillary sinus floor augmentation using different ratios of iliac or mandibular autograft and deproteinized bovine bone mineral. The results showed that the percentage of bone regeneration significantly increased with a higher ratio of autograft, regardless of the origin of the graft.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Vivian Wu, Engelbert A. J. M. Schulten, Marco N. Helder, Christiaan M. ten Bruggenkate, Nathalie Bravenboer, Jenneke Klein-Nulend
Summary: In this retrospective cohort study, it was found that maxillary tuberosity bone grafts showed better bone vitality and vascularization compared to mandibular retromolar bone grafts in patients undergoing maxillary sinus floor elevation for dental implant placement.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Review
Dentistry, Oral Surgery & Medicine
Pascal Valentini, Zvi Artzi
Summary: Sinus augmentation is a crucial step in posterior maxillary implant prosthesis reconstruction. Literature shows that the implant success rate is comparable to pristine bone. This review thoroughly discusses different osteotomy techniques, indications for 1 or 2-stage approaches, control of Schneiderian membrane integrity, and management of intra- and post-operative complications. The use of contemporary advanced techniques, such as lateral wall osteotomy, has shown reduced invasiveness and complication occurrences. A well-codified patient selection involving a rhinologist as part of the medical team is beneficial for early diagnosis. In-depth knowledge of anatomy, standardized surgical technique, and understanding of complication etiology and management are prerequisites for minimizing patient morbidity and achieving predictable successful outcomes.
PERIODONTOLOGY 2000
(2023)
Article
Medicine, General & Internal
Takamitsu Koga, Yuya Nakatani, Seigo Ohba, Masahito Hara, Yoshinori Sumita, Kazuhiro Nagai, Izumi Asahina
Summary: The clinical study aimed to evaluate the safety and preliminary efficacy of autologous freeze-drying platelet-rich plasma (FD-PRP) on bone regeneration in maxillary sinus floor augmentation. The results indicated the safety of x3FD-PRP in surgery and the progress of bone regeneration in patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Chemistry, Physical
Bruno Coelho Mendes, Rodrigo dos Santos Pereira, Carlos Fernando de Almeida Barros Mourao, Pietro Montemezzi, Anderson Maikon de Souza Santos, Jessica Monique Lopes Moreno, Roberta Okamoto, Eduardo Hochuli-Vieira
Summary: This study compared two beta-tricalcium phosphates with different particle sizes in human maxillary sinuses lifting, and evaluated osteoblast precursor cells and vascular formation using immunolabeling. The results showed that the evaluated bone substitutes had suitable outcomes for bone regeneration.
Article
Dentistry, Oral Surgery & Medicine
Claudio Stacchi, Antonio Rapani, Teresa Lombardi, Fabio Bernardello, Vanessa Nicolin, Federico Berton
Summary: This study evaluated the histomorphometric outcomes of lateral maxillary sinus augmentation in different areas of the same cavity and correlated the results to bucco-palatal sinus width (SW) and residual bone height (RBH). The study found that the newly formed mineralized tissue percentage (%NFMT) after 6 months varied in different anatomical areas and showed a strong negative correlation with SW, while no correlation was observed with RBH. Clinicians should consider SW as a guide for graft selection and the duration of the healing period, and researchers should use SW as a predictor variable when comparing regenerative outcomes of different biomaterials using the maxillary sinus as an experimental model.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Chemistry, Physical
Joao Paulo Bonardi, Rodrigo dos Santos Pereira, Carlos F. Mourao, Bruno Coelho Mendes, Adam Lowenstein, Pietro Montemezzi, Flavio Giubilato, Roberta Okamoto, Eduardo Hochuli-Vieira
Summary: The aim of this study was to compare two different forms of biphasic calcium phosphate (BCP) - granules and paste - in human maxillary sinus bone reconstruction. The results showed that both BCP granules and paste had suitable bone formation and high osteocalcin immunolabeling, indicating good bone calcification for dental implant placement.
Article
Chemistry, Physical
Francisco Correia, Daniel Humberto Pozza, Sonia Gouveia, Antonio Campos Felino, Ricardo Faria-Almeida
Summary: This study compared the performance of autologous bone grafts and porcine xenografts in maxillary sinus lift surgeries, showing no significant differences in bone level increases between the two materials. The porcine xenografts were found to be a reasonable alternative to autologous bone for sinus lift procedures.
Article
Medicine, General & Internal
Laura Andreea Schiller, Horia Mihail Barbu, Stefania Andrada Iancu, Silviu Brad
Summary: This study analyzed the correlation between surgical complexity and patient's sex, type of edentulism, and left or right side of the maxilla. The cone beam computed tomography records of 1192 maxillary sinuses were evaluated and statistically analyzed. The findings suggest that there is no correlation between surgical complexity and patient's sex, type of edentulism, and left or right side of the maxilla.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Materials Science, Multidisciplinary
Ricard Aceves-Argemi, Elisabet Roca-Millan, Beatriz Gonzalez-Navarro, Antonio Mari-Roig, Eugenio Velasco-Ortega, Jose Lopez-Lopez
Summary: This systematic review analyzed the use of titanium meshes in bone regeneration, showing an average bone gain of 4.3 mm, high survival and success rates of implants, but a significant risk of mesh exposure.
Article
Dentistry, Oral Surgery & Medicine
Luigi Canullo, Massimo Del Fabbro, Federica Colantonio, Roberta Iacono, Carlo Raffone, Andrea Pedetta, Shahnawaz Khijmatgar, Lior Shapira
Summary: This study aimed to evaluate the application of an hydroxyapatite-based, sugar cross-linked collagen sponge in transcrestal sinus floor augmentation. The results showed that the material had good manageability and promoted new bone formation with long-term stability, making it suitable for sinus floor augmentation.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Federico Mandelli, Tonino Traini, Paolo Ghensi
Summary: This case series evaluated the clinical and histological performance of customized-3D zirconia barriers in guided bone regeneration (GBR) procedures, showing successful outcomes in terms of bone regeneration and implantation outcomes without the need for additional bone augmentation. Further research with a larger sample size is needed to confirm the effectiveness of these barriers as an alternative to traditional membranes and meshes.
JOURNAL OF DENTISTRY
(2021)
Review
Chemistry, Physical
Shahnavaz Khijmatgar, Massimo Del Fabbro, Margherita Tumedei, Tiziano Testori, Niccolo Cenzato, Gianluca Martino Tartaglia
Summary: This study used network meta-analysis (NMA) to determine the influence of residual bone height (RBH) on new bone formation after lateral sinus augmentation, and found that there is no consistently superior grafting biomaterial for new bone formation.
Article
Cell & Tissue Engineering
Kei-ichiro Miura, Miho Sasaki, Seigo Ohba, Sawako Noda, Misa Sumi, Shinji Kamakura, Tetsu Takahashi, Izumi Asahina
Summary: This study evaluated the stability of dental implants 5 years after maxillary sinus floor augmentation with an octacalcium phosphate-collagen composite through clinical and radiological assessments. The success of the implants was confirmed by both types of evaluations, with no adverse events observed during the follow-up period.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Florian Beck, Karoline Maria Reich, Stefan Lettner, Patrick Heimel, Stefan Tangl, Heinz Redl, Christian Ulm
Summary: The study found that new bone formation in maxillary sinus floor augmentation follows a gradient from the native bone of the sinus floor towards the apical part of the augmentation area, with the distance to primordial bone playing a critical role in bone regeneration. This gradient is particularly pronounced in the molar region, showing a steeper decline in new bone formation compared to the premolar region.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Hamoun Sabri, Shayan Barootchi, Teresa Heck, Hom-Lay Wang
Summary: Taxonomy and classification of a disease are important for the diagnosis and treatment planning process and simplify communication between clinicians. This study critically appraised the classifications of single-rooted extraction sockets (ES) and proposed a new classification system based on a systematic review and the latest consensus in implant dentistry. Patient-related factors were found to be minimally considered in previous classifications, and a new system was proposed that combines patient-related factors, clinical, and radiographical parameters. The new classification system provides comprehensive inclusion of crucial parameters in implant placement and considers patient-related factors as modifiers following extraction.
JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Muhammad H. A. Saleh, Mustafa Tattan, Giuseppe Troiano, Himabindu Dukka, Andrea Ravida, Robert Levine, Hom-Lay Wang, Preston D. D. Miller
Summary: The study developed and evaluated a modified version of the periodontal risk score (PRS) that showed strong predictive capability for tooth loss due to periodontitis, providing a powerful tool for establishing tooth prognosis.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Bansari Shah, Monali Shah, Maria Geisinger, Muhammad H. A. Saleh, Mohamed Meghil, Hom-Lay Wang
Summary: This study demonstrated that scaling and root planing (SRP) can significantly reduce levels of CRP.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Cell & Tissue Engineering
Fangyu Zhu, Wenwen Liu, Pei Li, Han Zhao, Xuliang Deng, Hom-Lay Wang
Summary: This systematic review and network meta-analysis found that placing electric/magnetic materials in situ had more prominent effects than the electric/magnetic field on bone regeneration. Electrical materials with a zeta potential of -53 mV proved to be the most effective in increasing bone volume and bone mineral density. Magnetic materials with external magnetic fields showed the best results in increasing bone volume/tissue volume.
TISSUE ENGINEERING PART B-REVIEWS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Hamoun Sabri, Hom-Lay Wang
Summary: This study conducted a bibliometric analysis to identify the top 100 cited articles on peri-implantitis research. The findings revealed a focus on epidemiology rather than treatment strategies. The study also found no correlation between citation count and article age, indicating the continued impact of older articles. Overall, this research provides valuable insight into the characteristics and quality of peri-implantitis literature.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Alberto Monje, Ramon Pons, Javi Vilarrasa, Jose Nart, Hom-Lay Wang
Summary: This study investigated the clinical and radiographic significance of using a mixture of mineralized and demineralized allografts in the reconstructive therapy of peri-implantitis defects. The results showed that the use of this mixture was effective in clinically resolving peri-implantitis and gaining radiographic marginal bone level, while the addition of a barrier membrane did not enhance the treatment outcomes.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Medicine, General & Internal
Paolo Carosi, Claudia Lorenzi, Riccardo Di Gianfilippo, Piero Papi, Andrea Laureti, Hom-Lay Wang, Claudio Arcuri
Summary: This study examined the outcomes of self-tapping implants placed in extraction sockets or healed edentulous ridges and immediately temporized. After one year, the implants showed high stability and survival rates, as well as favorable esthetic outcomes. The use of these implants with immediate temporization was safe and reliable.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lorenzo Tavelli, Giovanni Zucchelli, Martina Stefanini, Giulio Rasperini, Hom-Lay Wang, Shayan Barootchi
Summary: Vertical soft tissue augmentation with implant submersion is an effective treatment for peri-implant soft tissue dehiscence with interproximal attachment loss in adjacent teeth, providing positive clinical, volumetric, and patient-reported outcomes.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Riccardo Di Gianfilippo, Chin-Wei Wang, Yuying Xie, Janet Kinney, James Sugai, William V. V. Giannobile, Hom-Lay Wang
Summary: This randomized clinical trial examined the changes in protein biomarker levels and bacterial profiles after surgical reconstructive therapy for peri-implantitis. The study also investigated the impact of adjunctive Er:YAG laser on protein biomarkers and microbial outcomes. The results showed that the surgical treatment significantly affected the levels of protein biomarkers and reduced the bacterial load.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lorenzo Tavelli, Jad Majzoub, Frederic Kauffmann, Maria Vera Rodriguez, Leonardo Mancini, Hsun-Liang Chan, Oliver D. D. Kripfgans, William V. V. Giannobile, Hom-Lay Wang, Shayan Barootchi
Summary: This study compared the efficacy of coronally advanced flap (CAF) versus tunnel technique (TUN) in covering mid-facial peri-implant soft tissue dehiscences (PSTDs). The results showed that CAF + CTG yielded superior outcomes in terms of PSTD coverage, keratinized mucosa width, mucosal thickness, and aesthetic evaluation compared to TUN + CTG. Therefore, CAF + CTG treatment can achieve excellent repair of PSTDs.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Editorial Material
Dentistry, Oral Surgery & Medicine
Kelvin I. Afrashtehfar, Carlos A. Jurado, Hom-Lay Wang
Summary: This study compared patient-reported outcomes (PROMs) of soft tissue substitutes vs autogenous grafts for peri-implant soft tissue augmentation. The results showed that soft tissue substitutes performed similarly or superior to autogenous grafts in terms of aesthetics, satisfaction, and quality of life. Therefore, a minimally invasive approach to soft tissue augmentation at implant sites is supported by the current evidence for implementation in daily clinical practice.
JOURNAL OF EVIDENCE-BASED DENTAL PRACTICE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Carlo Bertoldi, Ugo Consolo, Michele Lalla, Davide Zaffe, Donato Tanza, Francesco Cairo, Pierpaolo Cortellini
Summary: This study evaluated the outcomes and predictive factors for the long-term stability of root coverage using a sub-epithelial connective tissue graft. The results showed that the graft was effective in treating gingival recessions and facilitated long-term stability of clinical outcomes. Higher baseline recession area was associated with unfavorable clinical outcomes.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Correction
Pharmacology & Pharmacy
Alessandra Ottani, Maria Galantucci, Ettore Ardimento, Laura Neri, Fabrizio Canalini, Anita Calevro, Davide Zaffe, Ettore Novellino, Paolo Grieco, Daniela Giuliani, Salvatore Guarini
PHARMACOLOGICAL RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Carlo Barausse, Andrea Ravida, Lorenzo Bonifazi, Roberto Pistilli, Muhammad H. A. Saleh, Roberta Gasparro, Gilberto Sammartino, Hom-Lay Wang, Pietro Felice
Summary: This study investigated the use of extra-short (4-mm) implants to rehabilitate sites where regenerative procedures had failed, in order to avoid additional bone grafting. The results showed that out of 103 extra-short implants placed after failed regenerative procedures, 2 implants failed, resulting in a failure rate of 1.94% and an implant survival rate of 98.06%. The mean amount of marginal bone loss at 5 years post-loading was 0.32mm. Therefore, extra-short implants appear to be a good clinical option for managing reconstructive surgical failures, reducing surgical invasiveness and rehabilitation time.
INTERNATIONAL JOURNAL OF ORAL IMPLANTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Martina Stefanini, Shayan Barootchi, Lorenzo Tavelli, Matteo Marzadori, Claudio Mazzotti, Ilham Mounssif, Matteo Sangiorgi, Hamoun Sabri, Hom-Lay Wang, Giovanni Zucchelli
Summary: This study introduces a difficulty score for evaluating the treatment of localized gingival recessions with the coronally advanced flap. The score showed good reproducibility among different operators. Further clinical intervention studies are needed to validate the clinical significance of the score.
CLINICAL ORAL INVESTIGATIONS
(2023)