Article
Nutrition & Dietetics
Toshiko Tanaka, Sameera A. Talegawkar, Yichen Jin, Stephania Bandinelli, Luigi Ferrucci
Summary: This study found that adherence to a Mediterranean-type diet (MTD) is associated with lower frailty index (FI) scores in individuals over 65 years of age, particularly in those with low FI at baseline.
Article
Nutrition & Dietetics
Tracy Daou, Joelle Abi Kharma, Alexandra Daccache, Maya Bassil, Farah Naja, Berna Rahi
Summary: This study investigated the association between adherence to the Lebanese Mediterranean diet (LMD) and frailty among older adults in Lebanon. The results showed that higher adherence to the LMD was associated with lower prevalence of frailty, suggesting that dietary habits may have a positive impact on the health status of older adults.
Article
Geriatrics & Gerontology
Fatih Ergul, Fatih Sackan, Ahmet Koc, Ibrahim Guney, Muhammet Cemal Kizilarslanoglu
Summary: The study revealed that Turkish hospitalized older adults had low adherence to the Mediterranean diet. Unhealthy eating habits were associated with poor clinical outcomes such as malnutrition, frailty, prolonged hospital stays, and frequent emergency department visits.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2022)
Article
Nutrition & Dietetics
Helio Jose Coelho-Junior, Riccardo Calvani, Anna Picca, Stefano Cacciatore, Matteo Tosato, Francesco Landi, Emanuele Marzetti
Summary: Previous studies have shown that regular aerobic training and adherence to a Mediterranean diet can lower the prevalence of sarcopenia in older adults. However, the effect of their combination on sarcopenia indices is unknown.
Article
Geriatrics & Gerontology
Ellen Struijk, Teresa Fung, Frank Hu, Walter Willett, Fernando Rodriguez-Artalejo, Esther Lopez-Garcia, Mercedes Sotos-Prieto
Summary: The study found that higher consumption of red meat was associated with an increased risk of frailty in older women, even after adjusting for lifestyle factors, medication use, and dietary factors. Each additional serving of red meat per day was associated with a relative risk of 1.13 for total red meat, 1.08 for unprocessed red meat, and 1.26 for processed red meat.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Geriatrics & Gerontology
Ellen A. Struijk, Teresa T. Fung, Fernando Rodriguez-Artalejo, Heike A. Bischoff-Ferrari, Frank B. Hu, Walter C. Willett, Esther Lopez-Garcia
Summary: This study found that a higher intake of plant protein was associated with a lower risk of frailty in older women, while a higher intake of animal protein was associated with a higher risk of frailty. Additionally, substituting plant protein for animal protein significantly reduced the risk of frailty.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Editorial Material
Geriatrics & Gerontology
Simon Conroy, Matt Thomas
Summary: Geriatric medicine focuses on the care of older people, especially those with frailty. Comprehensive geriatric assessment is a holistic form of care that can reduce adverse outcomes. The specialty has evolved from community-based services to acute care, posing a challenge in delivering optimal geriatric care across the entire hospital.
Article
Geriatrics & Gerontology
Fereshteh Moradoghli, Ali Darvishpoor Kakhki, Roghayeh Esmaeili
Summary: Frailty is associated with decreased dignity in older adults, with frailty being the leading predictor of dignity. Providers should develop programs to prevent and reduce frailty in those at risk and enhance the dignity of already frail individuals.
Review
Cell Biology
Helio Jose Colho-Junior, Antonia Trichopoulou, Francesco Panza
Summary: The study found a significant association between high adherence to the Mediterranean diet and physical performance and cognitive function in older adults. Longitudinal analysis revealed that high adherence to the Mediterranean diet reduced the risk of global cognitive decline in non-demented older adults, but no significant associations were found with mobility problems, MCI, and dementia.
AGEING RESEARCH REVIEWS
(2021)
Article
Orthopedics
C. Xu, T. Liu, J. B. Driban, T. McAlindon, C. B. Eaton, B. Lu
Summary: The study found that following a Western dietary pattern was associated with an increased risk of knee osteoarthritis, while following a prudent pattern was associated with a reduced risk of knee OA. These associations were partially mediated through body mass index.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Review
Geriatrics & Gerontology
Ligia J. Dominguez, Carolina Donat-Vargas, Carmen Sayon-Orea, Maria Barberia-Latasa, Nicola Veronese, Jimena Rey-Garcia, Fernando Rodriguez-Artalejo, Pilar Guallar-Castillon, Miguel Angel Martinez-Gonzalez, Mario Barbagallo
Summary: Frailty is a geriatric syndrome with increasing frequency and dire consequences due to population aging. Nutritional factors, particularly the Mediterranean diet, play a crucial role in its pathogenesis. A systematic review and meta-analysis confirmed a robust association between higher adherence to the Mediterranean diet and reduced incident frailty. Promoting the Mediterranean diet as a high-quality dietary pattern adapted to different regions offers an opportunity to counteract the spread of unhealthy eating and lifestyle models and reduce frailty incidence.
EXPERIMENTAL GERONTOLOGY
(2023)
Article
Geriatrics & Gerontology
E. Ntanasi, S. Charisis, M. Yannakoulia, K. Georgiadi, V. Balomenos, M. H. Kosmidis, E. . Dardiotis, G. Hadjigeorgiou, P. Sakka, M. Maraki, N. Scarmeas
Summary: This prospective study found that older adults who adhered to the Mediterranean dietary pattern had a significantly lower incidence of frailty.
Editorial Material
Geriatrics & Gerontology
Jean Woo
Summary: Populations in Asian developed economies are rapidly ageing, resulting in increased frailty and dependency. Consideration of social determinants is crucial in designing equitable health and social care systems. Asian countries are developing integrated medical social care, with funding provided by long-term care insurance and philanthropy.
Article
Nutrition & Dietetics
Gloria Cubas-Basterrechea, Inaki Elio, Guzman Alonso, Luis Otero, Luis Gutierrez-Bardeci, Jesus Puente, Pedro Munoz-Cacho
Summary: This study found an inverse relationship between adherence to the Mediterranean diet and the prevalence of metabolic syndrome in an elderly population. Low adherence to the Mediterranean diet was associated with a higher prevalence of metabolic syndrome.
Article
Geriatrics & Gerontology
Marcel A. L. M. van Assen, Judith H. M. Helmink, Robbert J. J. Gobbens
Summary: This study aims to determine the association between lifestyle factors (smoking, alcohol use, nutrition, physical activity) and multidimensional frailty. The results showed that higher alcohol consumption, physical activity, healthy nutrition, and less smoking were associated with lower levels of frailty. Physical activity had the greatest impact on frailty.
Article
Substance Abuse
Eugenia Romano, Ruimin Ma, Davy Vancampfort, Lee Smith, Joseph Firth, Marco Solmi, Nicola Veronese, Brendon Stubbs, Ai Koyanagi
Summary: This study examined the association between cannabis use, fast-food consumption, overweight, and obesity among adolescents in 28 countries. The results showed a significant association between cannabis use and fast-food consumption, but no association with overweight and obesity. There was moderate heterogeneity among countries for obesity, and positive associations between cannabis use and obesity were observed in the Bahamas, Bangladesh, Namibia, and Nepal.
JOURNAL OF SUBSTANCE USE
(2023)
Article
Psychiatry
Marco Solmi, Markku Lahteenvuo, Christoph U. Correll, Antti Tanskanen, Jari Tiihonen, Heidi Taipale
Summary: Long-term use of prolactin-increasing antipsychotics is associated with an increased risk of low-energy fractures in people with schizophrenia, while prolactin-sparing antipsychotics show no significant association.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Rehabilitation
Nathalie Swinnen, Eling D. de Bruin, Vania Guimaraes, Chantal Dumoulin, Jacqueline De Jong, Riekje Akkerman, Mathieu Vandenbulcke, Brendon Stubbs, Davy Vancampfort
Summary: The study aims to explore the feasibility of using an exergame prototype for individuals with major neurocognitive disorder (MNCD) residing in a long-term care facility. The results suggest that the exergame prototype is accepted by individuals with MNCD and can have positive effects when they receive extensive guidance.
DISABILITY AND REHABILITATION
(2023)
Review
Rehabilitation
Davy Vancampfort, Tine Van Damme, Vanessa Albanio Machado, Ryan L. McGrath, Brendon Stubbs, Felipe B. Schuch
Summary: Based on studies of fibromyalgia patients, sedentary behavior is associated with pain, fatigue, and a more severe impact of the disease, independent of physical activity levels. However, little attention has been given to how to assess sedentary behavior in this population.
DISABILITY AND REHABILITATION
(2023)
Review
Clinical Neurology
Dimitri Fiani, Hannah Campbell, Marco Solmi, Jess G. Fiedorowicz, Chadi A. Calarge
Summary: Antidepressants have varied effects on the regulation of the cardiac autonomic nervous system. Selective serotonin reuptake inhibitors (SSRIs) are associated with reduced heart rate variability, while tricyclic antidepressants (TCAs) decrease parasympathetic function. Agomelatine may increase high frequency power. Further research is needed to understand the effects of SSRIs on cardiac ANS regulation after acute myocardial infarction and the effects of newer antidepressants.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Geriatrics & Gerontology
Nicola Veronese, Ai Koyanagi, Mario Barbagallo, Ligia J. Dominguez, Stefania Maggi, Pinar Soysal, Francesco Bolzetta, Giovanni Ruotolo, Alberto Castagna, Lee Smith
Summary: Pain, especially severe pain, is significantly associated with an increased risk of incident sarcopenia in older adults. The presence of pain at baseline, regardless of the sites, is a potential risk factor for sarcopenia over a 10-year follow-up period in a representative sample of the English older adult population.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Review
Behavioral Sciences
Samuele Cortese, Katherine McGinn, Mikkel Hojlund, Alan Apter, Celso Arango, Immaculada Baeza, Tobias Banaschewski, Jan Buitelaar, Josefina Castro-Fornieles, David Coghill, David Cohen, Edna Grunblatt, Pieter J. Hoekstra, Anthony James, Pia Jeppesen, Peter Nagy, Anne Katrine Pagsberg, Mara Parellada, Antonio M. Persico, Diane Purper-Ouakil, Veit Roessner, Paramala Santosh, Emily Simonoff, Dejan Stevanovic, Argyris Stringaris, Benedetto Vitiello, Susann Walitza, Abraham Weizman, Tamar Wohlfarth, Ian C. K. Wong, Gil Zalsman, Alessandro Zuddas, Carmen Moreno, Marco Solmi, Christoph U. Correll
Summary: In order to identify potential novel medications for child and adolescent mental health problems, we conducted a systematic search on clinical trial databases from 2010 to 2022. We included phase 2 or 3 randomized controlled trials (RCTs) of medications without regulatory approval in the US, Europe or Asia, and also RCTs of dietary interventions/probiotics. We found 234 ongoing or completed RCTs, with varying results on primary outcomes.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Behavioral Sciences
Michel Sabe, Adi Sulstarova, Chaomei Chen, Joshua Hyde, Emmanuel Poulet, Andre Aleman, Jonathan Downar, Valerie Brandt, Luc Mallet, Othman Sentissi, Michael A. Nitsche, Marom Bikson, Andre Russowsky Brunoni, Samuele Cortese, Marco Solmi
Summary: Interest in neurostimulation interventions has increased in recent decades, but a scientometric analysis of scientific knowledge and trends is lacking. A search using relevant keywords in the Web of Science Core Collection retrieved a total of 47,681 documents with 987,979 references. The study identified two prominent research trends: noninvasive and invasive brain stimulation, which have formed a cluster focused on evidence synthesis. Noteworthy emerging research trends include transcutaneous auricular vagus nerve stimulation, DBS/epilepsy in the pediatric population, spinal cord stimulation, and brain-machine interface. Further development can be fostered by enhancing communication between experts and encouraging translational research.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Nutrition & Dietetics
Mario Barbagallo, Nicola Veronese, Ligia J. Dominguez
Article
Psychiatry
Daniel T. Myran, Lyndsay D. Harrison, Michael Pugliese, Marco Solmi, Kelly K. Anderson, Jess G. Fiedorowicz, Christopher M. Perlman, Colleen Webber, Yaron Finkelstein, Peter Tanuseputro
Summary: This cohort study suggests that substance use, especially substance-induced psychosis, is associated with an increased risk of developing a schizophrenia spectrum disorder. Substance use without psychosis, although having a lower relative risk of transition, results in a greater absolute number of transitions. Several factors, including cannabis use, younger age, and male sex, are associated with a higher risk of transition.
Article
Immunology
Nicola Veronese, Nancy Zambon, Marianna Noale, Stefania Maggi
Summary: Vaccine acceptance is lower among poor people. Factors such as household size, age, education level, income, and number of health conditions significantly influence the probabilities of influenza and pneumonia vaccinations in this population.
Article
Health Care Sciences & Services
Federico Capone, Alberto Cipriani, Leonardo Molinari, Marianna Noale, Beatrice Gusella, Fabrizio Lucente, Sandro Savino, Antonella Bertomoro, Alois Saller, Sandro Giannini, Roberto Vettor
Summary: This study evaluates the clinical significance of iron deficiency (ID) screening and ferric carboxymaltose (FCM) treatment in acute decompensated heart failure (ADHF) patients. The results show a high prevalence of ID in ADHF patients, but FCM treatment had no significant impact on correcting the deficiency. Achieving the target dose of FCM and pursuing outpatient treatment are necessary for long-term clinical benefits.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Correction
Psychiatry
Lamiece Hassan, Chelsea Sawyer, Niels Peek, Karina Lovell, Andre F. Carvalho, Marco Solmi, George Tilston, Matthew Sperrin, Joseph Firth
Summary: Previous studies have shown that individuals with severe mental illness (SMI) face a higher risk of COVID-19 mortality. However, limited evidence is available regarding the risk post-vaccination. This study investigated COVID-19 mortality among individuals with schizophrenia and other SMIs before, during, and after the UK vaccine roll-out. The results revealed that people with SMI, particularly those with schizophrenia and bipolar disorder, were at a greater risk of COVID-19 mortality compared to matched controls. Despite efforts to prioritize vaccination for individuals with SMI, disparities in COVID-19 mortality still persist.
SCHIZOPHRENIA BULLETIN
(2023)
Review
Biochemistry & Molecular Biology
Marco Solmi, Samuele Cortese, Giovanni Vita, Michele De Prisco, Joaquim Radua, Elena Dragioti, Ole Kohler-Forsberg, Nanna M. Madsen, Christopher Rohde, Luis Eudave, Claudia Aymerich, Borja Pedruzo, Victoria Rodriguez, Stella Rosson, Michel Sabe, Mikkel Hojlund, Ana Catalan, Beatrice de Luca, Michele Fornaro, Giovanni Ostuzzi, Corrado Barbui, Gonzalo Salazar-de-Pablo, Paolo Fusar-Poli, Christoph U. Correll
Summary: This study aimed to identify predictors of key outcomes in mental disorders. Through an umbrella review, the researchers identified multivariable candidate predictors for response, remission, recovery, and relapse in various mental disorders. Several transdiagnostic predictors were found, but none were found for recovery. Factors such as disease-specific symptoms, gender, education level, quality of life, and functioning were identified as predictors for remission and relapse in different mental disorders.
MOLECULAR PSYCHIATRY
(2023)
Review
Geriatrics & Gerontology
Laura Cilona, Nicola Veronese, Diego Lalicata, Francesca Tantillo, Liliana Naro, Ligia J. Dominguez, Mario Barbagallo
Summary: This study aimed to systematically review the medical literature on spirituality and religiosity in patients with heart failure. The findings suggest that spirituality and religiosity may have positive associations with quality of life, cardiovascular outcomes, and mortality in heart failure patients.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
