Article
Nutrition & Dietetics
Yaren Zueguel, Caroline van Rossum, Marjolein Visser
Summary: This study provides recent data on the prevalence of undernutrition in Dutch community-dwelling older adults. The results show that currently one out of fourteen community-dwelling adults aged 65 years and older is undernourished. Factors such as being female, older, living alone, receiving formal home care, and having poor self-rated health, poor appetite, or mobility limitations are associated with a higher prevalence. Increasing awareness for early recognition and treatment is crucial.
Article
Multidisciplinary Sciences
Woldemariam Erkalo Gobena, Teramaj Wongel Wotale, Mesfin Esayas Lelisho, Wubishet Gezimu
Summary: This study investigated the prevalence and correlates of stunting among under-five children in Ethiopia. The study found that over a third of children in the area were stunted. Factors such as child's age, mother's education, mother's body mass index, place of residence, wealth index, and birth interval were found to significantly influence childhood stunting.
Article
Multidisciplinary Sciences
Ramendra Nath Kundu, Md Golam Hossain, Md Ahshanul Haque, Subir Biswas, Md Monimul Huq, Md Kamal Pasa, Md Sabiruzzaman, Premananda Bharati
Summary: This study aims to determine the factors of child undernutrition in Bangladesh using a single composite index of anthropometric failure (CIAF). The results show international disparities, with a high prevalence of undernutrition among Bengali children in both Bangladesh and India. Factors such as maternal undernutrition, lack of education, and poverty were identified as common contributors to undernutrition in both countries. The study recommends increased investment from governments to address child malnutrition and achieve the Sustainable Development Goals (SDGs).
Article
Public, Environmental & Occupational Health
Shela Sridhar, Janella S. Kang, Isabel Madzorera, Ethan Zulu, Joyce Makasa, Sally Bell Cross, Davidson H. Hamer
Summary: Understanding the prevalence of malnutrition in older children and adolescents is crucial for addressing food insecurity and undernutrition at all age groups. This study aimed to investigate the nutritional status of adolescents and older children in Zambia and explore the impact of food security.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Nutrition & Dietetics
Jaime J. Gahche, Mary B. Arensberg, Mary Weiler, Johanna T. Dwyer
Summary: Both undernutrition and frailty have negative impacts on the health and functional outcomes of the older adult population. US national surveys currently only include limited health measures that can be used to identify undernutrition and frailty risk in older adults. Therefore, adding simple screening measures such as grip strength, unintentional weight loss, and loss of appetite to national surveys could improve risk assessment and help set national goals to reduce the prevalence of undernutrition and frailty.
ADVANCES IN NUTRITION
(2021)
Article
Multidisciplinary Sciences
Maryam Siddiqa, Amber Zubair, Asifa Kamal, Muhammad Ijaz, Tahani Abushal
Summary: The objective of this study was to identify the risk factors for malnutrition among under-five children in Pakistan. The study analyzed data from the Pakistan Demographic and Health Survey (PDHS 2017-18) using quantile regression analysis. The findings showed that malnutrition was more prevalent among boys and children of older mothers. Factors such as small body size at birth, maternal education level, household poverty, rural residence, and inadequate breastfeeding practices had a negative effect on different measures of malnutrition. On the other hand, older maternal age and higher birth order number had a positive effect on under-nutrition. Elderly and smoking mothers were identified as associated risk factors for both stunting and being underweight. Proper breastfeeding practices, better economic status, average or above-average birth weight, and milk consumption were found to be protective factors against malnutrition in Pakistan.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
U. R. Saha, C. F. A. van Wesenbeeck
Summary: Bangladesh's progress in child nutrition has varied across different regions. This study uses national data to explore the relationship between various factors and childhood stunting. The findings suggest that targeted policies have been successful in some regions, but not in others. The challenge lies in the implementation of these policies.
Article
Multidisciplinary Sciences
S. M. Jubaidur Rahman, N. A. M. Faisal Ahmed, Md Menhazul Abedin, Benojir Ahammed, Mohammad Ali, Md Jahanur Rahman, Md Maniruzzaman
Summary: This study focused on using machine learning algorithms to detect and predict the risk factors of malnutrition among Bangladeshi under-five children, with logistic regression identifying potential risks and ML classifiers like SVM, RF, and LR used for prediction. RF showed the highest accuracy in classifying stunted, wasted, and underweight children, which can help policymakers in reducing malnutrition prevalence.
Article
Immunology
Pranay Sinha, Chinnaiyan Ponnuraja, Nikhil Gupte, Senbagavalli Prakash Babu, Samyra R. Cox, Sonali Sarkar, Vidya Mave, Mandar Paradkar, Chelsie Cintron, S. Govindarajan, Aarti Kinikar, Nadesan Priya, Sanjay Gaikwad, Balamugesh Thangakunam, Arutselvi Devarajan, Mythili Dhanasekaran, Jeffrey A. Tornheim, Amita Gupta, Padmini Salgame, Devashyam Jesudas Christopher, Hardy Kornfeld, Vijay Viswanathan, Jerrold J. Ellner, C. Robert Horsburgh, Akshay N. Gupte, Chandrasekaran Padmapriyadarsini, Natasha S. Hochberg
Summary: Undernutrition is a major risk factor for poor treatment outcomes in tuberculosis. Severe undernutrition at treatment initiation and prior to TB disease, as well as lack of weight gain during intensive therapy, are associated with unfavorable outcomes.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Nutrition & Dietetics
Andrea Elliott, Simone Gibson, Judy Bauer, Anna Cardamis, Zoe Davidson
Summary: Malnutrition is a global health concern that affects patient outcomes, hospital stay duration, and healthcare costs. While there is extensive research on undernutrition in hospitalized patients, data on overnutrition is limited. This study examines the prevalence of both under and overnutrition in a hospitalized population and evaluates the dietetic care provided to obese patients using the Nutrition Care Process Model. The findings reveal a high prevalence of overweight and obese patients, lower malnutrition risk profiles in these patients, and a lack of nutrition diagnosis following the recommended model.
Article
Nutrition & Dietetics
Diego Casas-Deza, Vanesa Bernal-Monterde, Elena Betore-Glaria, Ana Belen Julian-Gomara, Carmen Yague-Caballero, Alejandro Sanz-Paris, Eva Maria Fernandez-Bonilla, Javier Fuentes-Olmo, Jose M. Arbones-Mainar
Summary: This study evaluated the ability of the Liver Disease Undernutrition Screening Tool (LDUST) to predict mortality and decompensation in outpatients with clinically significant portal hypertension (CSPH). The results showed that LDUST could help identify patients in need of nutritional supplementation and intervention. Combining LDUST with Child and MELD scores improved their decompensation prediction.
Review
Geriatrics & Gerontology
Laura A. Bardon, Clare A. Corish, Meabh Lane, Maria Gabriella Bizzaro, Katherine Loayza Villarroel, Michelle Clarke, Lauren C. Power, Eileen R. Gibney, Patricia Dominguez Castro
Summary: This review critically examines the evidence for the most frequently reported sociodemographic factors and determinants of malnutrition in older adults, with differences identified according to rates of ageing. Factors associated with malnutrition from the food intake, social, and disease-related domains increase in severity in the accelerated ageing category. This study highlights the importance of understanding specific factors associated with malnutrition in older adults based on their rate of ageing to improve identification and prevention strategies.
Article
Multidisciplinary Sciences
Mohaimen Mansur, Awan Afiaz, Md. Saddam Hossain
Summary: This paper demonstrates the importance of studying interactions among various sociodemographic risk factors of childhood stunting in Bangladesh using an interpretable machine learning method. Results show the necessity of tailored intervention programs for children based on their distinct risk profiles and sociodemographic characteristics. The study highlights the significant impact of the interplay between multiple factors on childhood stunting.
Article
Multidisciplinary Sciences
Chii-Chii Chew, Xin-Jie Lim, Lee-Lan Low, Kin-Mun Lau, Maziana Kari, Ummi Kalthom Shamsudin, Philip Rajan
Summary: The indigenous children in Peninsular Malaysia face significant challenges related to malnutrition, including limited access to nutritious food and healthcare services, as well as cultural barriers. Healthcare providers need to possess cross-cultural communication skills and adapt to the unique environment to effectively address these challenges and implement successful nutrition programs. Collaboration between various stakeholders is crucial in overcoming the multifactorial challenges faced by healthcare providers in serving the indigenous communities.
Review
Food Science & Technology
Karolina Kujawowicz, Iwona Mironczuk-Chodakowska, Anna Maria Witkowska
Summary: Undernutrition and inflammatory processes are predictors of early mortality in the elderly, and there is a need for rapid and accurate diagnosis. SIRT1 has shown potential as a marker for undernutrition, and this article summarizes the available studies on its association with undernutrition in older people. The literature suggests that low SIRT1 levels in the blood of older individuals may be linked to increased risk of severe undernutrition associated with inflammation and systemic metabolic changes, rather than physiological aging processes.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Editorial Material
Gastroenterology & Hepatology
Maria Letizia Petroni, Lucia Brodosi, Giulio Marchesini
ANNALS OF HEPATOLOGY
(2023)
Article
Nutrition & Dietetics
Lorenzo Donini, Elliot Berry, Frans Folkvord, Leon Jansen, Frederic Leroy, Omer SimSek, Fabio Fava, Marco Gobbetti, Andrea Lenzi
Summary: The 2022 Front-of-pack labels (FOPLs) aim to communicate the health value of food items to consumers and support public health policies. However, directive FOPLs like Nutri-Score have drawbacks such as overemphasizing selected nutritional factors, ignoring the food matrix and holistic aspects of nourishment, and allowing ultra-processed products. In contrast, informative FOPLs focus on individual portions and avoid classifying foods as healthy or unhealthy. The adoption of FOPLs has not been effectively linked to improvements in health outcomes.
Article
Nutrition & Dietetics
Maria Sifakaki, Konstantinos Gkiouras, Helen M. M. Lindqvist, Georgios Marakis, Anastasia Petropoulou, Lorenzo M. M. Donini, Dimitrios P. P. Bogdanos, Maria G. G. Grammatikopoulou
Summary: This study aimed to evaluate the tendencies of orthorexia nervosa (ON) in patients with rheumatoid arthritis (RA). The results showed that most patients had ON tendencies, with a higher tendency in female patients and a lower tendency in older patients with higher body mass index. These findings highlight the importance of awareness and screening for ON in patients with RA.
Article
Nutrition & Dietetics
Maria Letizia Petroni, Lucia Brodosi, Angelo Armandi, Francesca Marchignoli, Elisabetta Bugianesi, Giulio Marchesini
Summary: A study compared a web-based intervention (WBI) with a standard group-based intervention (GBI) for the prevention and treatment of non-alcoholic fatty liver disease (NAFLD), and found that both interventions had similar effects on weight loss and the risk of developing diabetes in NAFLD patients. The study followed 546 NAFLD individuals for 60 months and observed similar changes in weight and incidence of diabetes between the two intervention groups.
Review
Nutrition & Dietetics
Edoardo Mocini, Camillo Cammarota, Francesco Frigerio, Luca Muzzioli, Claudia Piciocchi, Doriana Lacalaprice, Fabio Buccolini, Lorenzo Maria Donini, Alessandro Pinto
Summary: Digital anthropometry (DA) has been developed for body composition evaluation and postural analysis. This review examines the current state of DA technology and evaluates the reliability and accuracy of available technologies on the market. DA shows high reliability and accuracy, especially in assessing obese patients and correlates well with conventional anthropometry and body composition estimates. DA is cost-effective and time-efficient, making it a useful screening tool before more expensive imaging techniques or as an alternative to other less affordable techniques. However, caution is needed in interpreting results due to the heterogeneity of available studies. Furthermore, there is a need for integrated technologies to analyze body composition according to multi-compartmental models.
Article
Biochemistry & Molecular Biology
Francesco Frigerio, Maria De Marinis, Francesca Camardella, Vito Cantisani, Alessandro Pinto, Marco Bernardi, Carla Lubrano, Lucio Gnessi, Massimo Federici, Lorenzo Maria Donini, Eleonora Poggiogalle
Summary: Accumulating evidence suggests a connection between sarcopenic obesity and NAFLD, but the impact of NAFLD on muscle contractility remains uncertain. This study aimed to investigate the effect of NAFLD on dynapenia in patients with sarcopenic obesity. The results showed that despite no significant differences in body weight, glycometabolic parameters, and hepatic steatosis prevalence, patients with sarcopenic obesity had worse serum lipid profiles, higher body fat, and lower skeletal muscle mass. There was a positive correlation between disposition index and muscle quality index after controlling for menopause and body fat percentage.
Editorial Material
Gastroenterology & Hepatology
Santo Colosimo, Giulio Marchesini
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Endocrinology & Metabolism
Valeria Hasenmajer, Rosario Ferrigno, Marianna Minnetti, Bianca Pellegrini, Andrea M. Isidori, Andrea Lenzi, Mariacarolina Salerno, Marco Cappa, Li Chan, Maria Cristina De Martino, Martin O. Savage
Summary: Adrenal insufficiency is a severe endocrine disorder characterized by insufficient secretion of glucocorticoid and/or mineralocorticoid due to impaired adrenal function or inadequate adrenal stimulation. This review focuses on rare genetic causes of primary adrenal insufficiency with isolated glucocorticoid or combined glucocorticoid and mineralocorticoid deficiencies, as well as rare syndromes of isolated mineralocorticoid deficiency. The diagnosis of these rare genetic forms of pediatric adrenal insufficiency is challenging due to their clinical heterogeneity and rarity, and this review aims to provide an overview of their genetic and clinical features, as well as diagnostic and therapeutic approaches.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2023)
Review
Endocrinology & Metabolism
E. Delli Paoli, S. Di Chiano, D. Paoli, A. Lenzi, F. Lombardo, F. Pallotti
Summary: Androgen insensitivity syndrome (AIS) is a disorder characterized by peripheral androgen resistance due to androgen receptor mutations in individuals with a 46 XY karyotype. The severity of hormone resistance determines the wide variety of phenotypes. A multidisciplinary approach involving physicians, surgeons, and psychologists is recommended for the management of AIS, to provide support in gender identity choices and appropriate therapeutic decisions.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Gastroenterology & Hepatology
Maria Letizia Petroni, Santo Colosimo, Lucia Brodosi, Angelo Armandi, Flavio Bertini, Danilo Montesi, Elisabetta Bugianesi, Giulio Marchesini
Summary: Web-based behavioural intervention is feasible and effective in non-alcoholic fatty liver disease (NAFLD), expanding the cohort involved in behavioural programs and reducing the risk of progressive disease.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Nutrition & Dietetics
Maryam Pourhassan, Tommy Cederholm, Lorenzo M. Donini, Eleonora Poggiogalle, Ursula Schwab, Rikke Lundsgaard Nielsen, Aino Leegaard Andersen, Sylwia Malgorzewicz, Dorothee Volkert, Rainer Wirth
Summary: The impact of inflammation on food intake is unclear, but it is a key risk factor for malnutrition. A study of geriatric hospitalized patients across Europe found that inflammation was the most prominent risk factor for low food intake and malnutrition, surpassing other factors such as age, gender, infection, and comorbidity. A CRP level of ≥3.0 mg/dL is associated with a high risk of malnutrition in hospitalized geriatric patients.
Article
Endocrinology & Metabolism
G. Marchesini, D. Gibertoni, C. Giansante, V. Perlangeli, R. Grilli, L. Scudeller, C. Descovich, P. Pandolfi
Summary: This study investigated the impact of diabetes in immigrants on the Italian healthcare system and their compliance with standard protocols. The findings showed that the prevalence of diabetes was slightly higher in immigrants compared to the general population, and immigrants had poorer metabolic control and adherence to diagnostic and therapeutic protocols.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2023)
Article
Endocrinology & Metabolism
Santo Colosimo, Sandip Kumar Mitra, Tirthankar Chaudhury, Giulio Marchesini
Summary: This review investigates the mechanisms through which metabolic flexibility and insulin resistance contribute to the progression of NAFLD and heart disease. Both play a critical role in glucose and lipid metabolism, and disruption of metabolic flexibility leads to abnormal lipid metabolism and fat accumulation in the liver, while insulin resistance affects cardiac glucose metabolism and lipid metabolism, leading to impaired cardiac function. Regular physical activity promotes metabolic flexibility, while weight loss achieved through calorie restriction improves insulin sensitivity.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Psychiatry
Lucia Brodosi, Michele Stecchi, Francesca Marchignoli, Elisabetta Lucia, Lucia Magnani, Valeria Guarneri, Maria Letizia Petroni, Giulio Marchesini, Loris Pironi
Summary: This study aimed to evaluate the association between metabolic dysfunction-associated steatotic liver disease (MASLD) and eating disorders. The results showed that binge eating disorder (BED) was present in approximately 17.8% of MASLD patients screened in a specialized metabolic disorders unit. This study highlights the importance of addressing eating disorders in the treatment of MASLD.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2023)
Review
Endocrinology & Metabolism
Francesco Pallotti, Sandro C. Esteves, Fabiana Faja, Alessandra Buonacquisto, Anna Chiara Conflitti, Maria Neve Hirsch, Andrea Lenzi, Donatella Paoli, Francesco Lombardo
Summary: COVID-19 may have indirect effects on male reproductive system, but there is limited evidence to support this. Despite the low quality of available evidence, careful andrological evaluation and follow-up for men recovering from COVID-19 are still necessary.
