Article
Rehabilitation
Umesh M. Venkatesan, Deepa M. Ramanathan-Elion
Summary: This article discusses the theoretical foundations and conceptual framework of psychoeducation in cognitive rehabilitation interventions, and proposes the use of treatment theory and the Rehabilitation Treatment Specification System to personalize educational content and improve health literacy in Service Members and Veterans affected by mild traumatic brain injury.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Psychiatry
Shayna J. Fink, Delaney K. Davey, McKenna S. Sakamoto, Catherine Chanfreau-Coffinier, Alexandra L. Clark, Lisa Delano-Wood, Victoria C. Merritt
Summary: The study examined subjective cognitive and psychiatric functioning in post-deployed military Veterans who participated in the Veterans Health Administration's TBI Screening and Evaluation Program. The results showed that Veterans who screened positive for TBI, regardless of diagnosis, had poorer cognitive and psychiatric health.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Rehabilitation
Dawn Neumann, Shannon B. Juengst, Charles H. Bombardier, Jacob A. Finn, Shannon R. Miles, Yue Zhang, Richard Kennedy, Amanda R. Rabinowitz, Amber Thomas, Laura E. Dreer
Summary: This study aimed to determine anxiety trajectories and predictors up to 10 years after traumatic brain injury (TBI). The results showed that factors such as race, insurance, pre-injury mental health treatment, multiple TBIs with loss of consciousness, violent injury, and years post-TBI were associated with higher levels of anxiety. Three different anxiety trajectories were identified, with the high-increasing and high-decreasing groups having consistently mild or higher anxiety scores throughout the 10-year period.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Biochemistry & Molecular Biology
Ethan G. Smith, James Hentig, Carina Martin, Chelsea Wagner, Vivian A. Guedes, Katie A. Edwards, Christina Devoto, Kerri Dunbar, Michael J. Roy, Jessica M. Gill
Summary: This study found a significant association between PTSD symptom severity and levels of circulating pro-inflammatory cytokines in military service members with a history of TBI, suggesting unique cytokine profiles related to neurobehavioral outcomes associated with TBI and PTSD in the military TBI population.
Article
Clinical Neurology
Umesh M. Venkatesan, Amanda R. Rabinowitz, Stephanie P. Wolfert, Frank G. Hillary
Summary: The study found a specific association between the duration of post-traumatic amnesia (doPTA) and chronic memory deficits after traumatic brain injury (TBI), even after controlling for other cognitive abilities. Long doPTA was related to impairment in memory, but not processing speed and executive functioning. Subjective memory beliefs were associated with memory performance, but not with doPTA.
NEUROREHABILITATION
(2021)
Article
Neurosciences
Victoria C. Merritt, Tracey A. Brickell, Jason M. Bailie, Lars Hungerford, Sara M. Lippa, Louis M. French, Rael T. Lange
Summary: This study aimed to examine the relationship between resilience and self-reported neurobehavioral functioning following traumatic brain injury (TBI) in U.S. military service members and veterans (SMVs). The results showed that resilience and PTSD strongly influence neurobehavioral functioning among SMVs following TBI, regardless of injury group and time since injury.
Article
Psychology, Clinical
Molly J. Sullan, Laura D. Crocker, Kelsey R. Thomas, Henry J. Orff, Delaney K. Davey, Sarah M. Jurick, Elizabeth W. Twamley, Sonya B. Norman, Dawn M. Schiehser, Robin Aupperle, Amy J. Jak
Summary: Poor sleep quality is common among Veterans with posttraumatic stress disorder (PTSD) and history of traumatic brain injury (TBI). However, the study found that trauma-focused treatment did not lead to improvement in sleep quality, and baseline poor sleep quality was associated with less improvement in PTSD symptoms and cognitive complaints.
BEHAVIOUR RESEARCH AND THERAPY
(2021)
Article
Clinical Neurology
Alana M. Campbell, Eric B. Elbogen, Jacqueline L. Johnson, Robert M. Hamer, Aysenil Belger
Summary: The study found that veterans exhibited heightened responsiveness to background information and reduced ERP responses to task-relevant information. Impulsivity predicted modulation of the P3b across stimulus conditions. These results may indicate amplified internal states leading to neural noise and reduced ability to modulate relevant responses.
CLINICAL NEUROPHYSIOLOGY
(2021)
Review
Clinical Neurology
Yang Liu, Xiaomeng Yao, Jinghua Qian
Summary: This study analyzes the international trends and global productivity of traumatic brain injury (TBI) rehabilitation research through bibliometric approaches and visualization methods. The results show that TBI rehabilitation research has gained increasing attention and has experienced significant growth in publications and citations in the past three decades. The research is characterized by its multidisciplinary approach, involving fields such as rehabilitation, neurosciences, and clinical neurology. The analysis also reveals emerging research subjects that could inform future research directions.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Andrea L. C. Schneider, Carrie B. Peltz, Yixia Li, Amber Bahorik, Raquel C. Gardner, Kristine Yaffe
Summary: This study found that traumatic brain injury (TBI) is associated with long-term stroke risk, with differences observed in age, sex, race and ethnicity, and time since TBI diagnosis. The highest risk of stroke occurs in the first year after TBI diagnosis, but the risk remains elevated for more than 10 years. Both mild and moderate/severe/penetrating TBI increase the risk of stroke compared to individuals without TBI. Older individuals have a stronger association between TBI and stroke, while Black veterans have a weaker association compared to other races and ethnicities. These findings suggest that veterans with prior TBI should be targeted for primary stroke prevention measures.
Article
Public, Environmental & Occupational Health
Anna Zogas
Summary: This study aimed to understand the experiences of military veterans and healthcare providers in identifying the personal histories of combat-related mild traumatic brain injury (mTBI) months or years after the injury. The study found that veterans and staff had different understandings of the value of neuroimaging and diagnostic certainty in clinical care. Improving patient-provider communication can be achieved through conversations about common norms of diagnosis and educating patients about the diagnostic process.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Health Care Sciences & Services
Megan Miller, Rhonda Williams, Kathleen Pagulayan, Jason Barber, Dawn M. Ehde, Jeanne Hoffman
Summary: This study investigated the sleep patterns in Veterans with both traumatic brain injury (TBI) and chronic pain. The results showed that more severe insomnia symptoms were associated with higher depression and PTSD symptoms, as well as slower processing speed. Improving sleep quality in this population may be crucial for improving outcomes following TBI.
DISABILITY AND HEALTH JOURNAL
(2022)
Article
Critical Care Medicine
Jared A. Rowland, Jennifer R. Stapleton-Kotloski, Sarah L. Martindale, Emily E. Rogers, Anna S. Ord, Dwayne W. Godwin, Katherine H. Taber
Summary: The study evaluated the impact of traumatic brain injury and blast exposure on functional brain connectomes in post-deployment, combat-exposed veterans. Results indicated significant interactions between blast-related mild TBI and PTSD, with a main effect of blast-related mild TBI on the functional brain connectomes.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Clinical Neurology
Katherine Musacchio Schafer, Emma Wilson, Thomas Joiner
Summary: Suicide is a widespread public health concern, with traumatic brain injuries (TBIs) and lack of social integration identified as risk factors. This cross-sectional study of 1469 military Veterans found that TBI was negatively associated with social integration and positively with suicidality. Social integration was also negatively associated with suicidality. The study suggests that lack of social integration may promote suicidality in the context of TBI and highlights the potential use of social integration as an intervention for suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Juan Carlos Arango-Lasprilla, Jack D. Watson, Miriam J. Rodriguez, Daniela Ramos-Usuga, Guido Mascialino, Paul B. Perrin
Summary: This study aimed to determine the demographic and injury-related predictors of employment probability trajectories during the first 10 years after traumatic brain injury (TBI) among Hispanics. The results showed that younger age, shorter posttraumatic amnesia duration, longer years of education, pre-injury employment, higher annual earnings, and non-violent mechanism of injury were associated with higher employment probability trajectories among Hispanics with TBI. Culturally adapted treatment programs incorporating vocational rehabilitation and employment programs are needed for Hispanics with TBI who present with these risk factors.
NEUROREHABILITATION
(2022)
Article
Clinical Neurology
Henry W. Mahncke, Joseph DeGutis, Harvey Levin, Mary R. Newsome, Morris D. Bell, Chad Grills, Louis M. French, Katherine W. Sullivan, Sarah-Jane Kim, Annika Rose, Catherine Stasio, Michael M. Merzenich
Summary: This study evaluated the efficacy of self-administered plasticity-based cognitive training for individuals with a history of mild traumatic brain injury and cognitive impairment. The treatment group showed significant improvement in cognitive function compared to the active control group, with equivalent results in depressive and cognitive symptoms between the two groups.
Article
Clinical Neurology
Cassandra L. Pattinson, Tracey A. Brickell, Jason Bailie, Lars Hungerford, Sara M. Lippa, Louis M. French, Rael T. Lange
Summary: This study examined the association between sleep disturbances and neurobehavioral outcome following traumatic brain injury (TBI) and found that sleep disturbances were significantly associated with worsened neurobehavioral functioning. When experienced concurrently with posttraumatic stress disorder, sleep disturbances posed a significant burden on service members and veterans.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2021)
Article
Medicine, General & Internal
Rose K. Sia, Denise S. Ryan, Daniel Brooks, Janice M. Kagemann, Kraig S. Bower, Louis M. French, Grant A. Justin, Marcus H. Colyer
Summary: The study found that the visual and health-related quality of life among U.S. military service members with combat ocular trauma (COT) is generally good in the long term. However, those with both COT and a history of traumatic brain injury (TBI) showed significantly worse functioning in several domains compared to those without TBI.
Article
Psychology, Clinical
Tracey A. Brickell, Louis M. French, Jamie K. Sullivan, Nicole V. Varbedian, Megan M. Wright, Rael T. Lange
Summary: Close to half of spouse caregivers assisting service members and veterans following traumatic brain injury reported unhealthy family functioning, which was associated with worse caregiver health-related quality of life. However, healthy family functioning may mitigate poor HRQOL. Despite military policy limitations on family services, investing in caregiver and family-focused programs could improve outcomes for military families at a relatively modest cost.
PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY
(2022)
Article
Neurosciences
Victoria C. Merritt, Tracey A. Brickell, Jason M. Bailie, Lars Hungerford, Sara M. Lippa, Louis M. French, Rael T. Lange
Summary: This study aimed to examine the relationship between resilience and self-reported neurobehavioral functioning following traumatic brain injury (TBI) in U.S. military service members and veterans (SMVs). The results showed that resilience and PTSD strongly influence neurobehavioral functioning among SMVs following TBI, regardless of injury group and time since injury.
Article
Health Care Sciences & Services
Rael T. Lange, Louis M. French, Jason M. Bailie, Victoria C. Merritt, Cassandra L. Pattinson, Lars D. Hungerford, Sara M. Lippa, Tracey A. Brickell
Summary: This study demonstrates the clinical utility of post-traumatic stress disorder (PTSD), low resilience, and poor sleep as risk factors for predicting neurobehavioral outcomes following traumatic brain injury (TBI). These risk factors, both individually and in combination, can be used for targeted early interventions in clinical practice.
QUALITY OF LIFE RESEARCH
(2022)
Article
Audiology & Speech-Language Pathology
Jennifer Rae Myers, Nancy Pearl Solomon, Rael T. Lange, Louis M. French, Sara M. Lippa, Tracey A. Brickell, Shelby Staines, Jenna Nelson, Doug S. Brungart, Carl A. Coelho
Summary: This exploratory study investigated discourse production in service members and veterans with mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD). The results revealed significant differences in global coherence and word count between different groups, while no significant differences were observed in other features. Structural features may serve as potential markers of cognitive communication deficits in individuals with mTBI.
AMERICAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
(2022)
Article
Psychology, Clinical
Tracey A. Brickell, Louis M. French, Nicole V. Varbedian, Jessie M. Sewell, Faith C. Schiefelbein, Megan M. Wright, Rael T. Lange
Summary: This study explored the relationship satisfaction and HRQOL among spouse caregivers of SMV with comorbid MTBI and PTSD, identifying factors such as anxiety, family disruption, and vigilance as strong predictors of relationship satisfaction. The Dissatisfied group consistently showed higher clinically elevated scores compared to the Satisfied group, highlighting the need for more integrated behavioral health treatment for family members in military TBI and PTSD care systems.
Article
Medicine, General & Internal
Remigio Flor, Boonkit Purt, Rose K. Sia, Denise S. Ryan, Janice M. Kagemann, Brittany E. Powell, Louis M. French, Hind Beydoun, Grant A. Justin, Marcus H. Colyer
Summary: This study is the first to evaluate the association between combat-related ocular injuries and traumatic brain injury (TBI). The results show that patients with combat-related ocular injuries are more likely to have a TBI, with closed globe injury being the only statistically significant predictive factor.
Article
Public, Environmental & Occupational Health
Tracey A. Brickell, Louis M. French, Megan M. Wright, Rael T. Lange
Summary: This study aimed to examine the relationship between SMV aggression and HRQOL in intimate partners of post-9/11 male SMVs. The results showed that caregivers of SMVs with moderate to severe aggression reported poor HRQOL, suggesting the importance of screening and treating aggression in SMVs and addressing the health needs of their caregivers.
WOMENS HEALTH ISSUES
(2022)
Article
Clinical Neurology
Sara M. Lippa, Rael T. Lange, Clifton L. Dalgard, Anthony R. Soltis, Vivian A. Guedes, Tracey A. Brickell, Louis M. French, Jessica Gill
Summary: This study demonstrates for the first time that APOE genotype is related to serum tau levels following mild traumatic brain injury (mTBI), with APOE e4 carriers having higher levels and APOE e2 carriers having lower levels, suggesting a possible protective effect.
FRONTIERS IN NEUROLOGY
(2022)
Article
Critical Care Medicine
Rael T. Lange, Sara Lippa, Tracey A. Brickell, Jessica Gill, Louis M. French
Summary: This study examines the association between serum tau, NFL, GFAP, and UCHL-1 concentrations and longitudinal changes in neurobehavioral functioning after military-related TBI. The study finds that elevated concentrations of these biomarkers are associated with the deterioration of neurobehavioral symptoms, suggesting their potential as prognostic tools for identifying individuals at risk of poor outcome after TBI.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Critical Care Medicine
Sara M. Lippa, Ping-Hong Yeh, John Ollinger, Tracey A. Brickell, Louis M. French, Rael T. Lange
Summary: The extant literature on the relationship between diffusion tensor imaging (DTI) and cognition following traumatic brain injury (TBI) is limited by small sample sizes and inappropriate control groups. This study examined DTI metric differences between different TBI groups and found a dose-response relationship between TBI severity and the strength of the relationship between white matter integrity and cognitive performance. Unlike previous findings, this study did not find any differences in DTI metrics between controls, mild TBI, and complicated TBI.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Audiology & Speech-Language Pathology
Daniel S. Talian, Megan M. Eitel, Danielle J. Zion, Stefanie E. Kuchinsky, Louis M. French, Tracey A. Brickell, Sara M. Lippa, Rael T. Lange, Douglas S. Brungart
Summary: This study describes normative ranges and interrater reliability of vestibular and balance function tests in a cohort of Service Members and Veterans. The results show excellent interrater reliability for most tests, providing important information for clinicians and scientists.
AMERICAN JOURNAL OF AUDIOLOGY
(2023)
Article
Audiology & Speech-Language Pathology
Alyssa Davidson, Megan Eitel, Rael T. Lange, Louis M. French, Sara Lippa, Tracey A. Brickell, Douglas Brungart
Summary: This article proposes an alternative technique for measuring Masking Level Difference (MLD) based on manual audiometry, which is just as reliable as the CD-based Wilson test. The study found that although the manual and Wilson MLD techniques produced significantly different thresholds, they can be transformed to obtain approximately equivalent scores. The manual MLD technique also showed stronger correlations with subjective and objective hearing measures compared to the Wilson technique.
JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH
(2023)
