Article
Agriculture, Dairy & Animal Science
Kanokwan Keadwut, Pakthorn Lewchalermwong, Nathanat Inpithuk, Piyathip Choochalermporn, Ananya Pongpradit, Nattika Koatsang, Nirut Suwanna
Summary: This study compared the efficacy and postoperative overshunting between the low-pressure valve and medium-pressure valve ventriculoperitoneal shunt in dogs with severe hydrocephalus. The results showed overshunting in four dogs who received low-pressure valve placement. Medium-pressure valve is recommended for overshunting prevention, while low-pressure valve placement improves cognitive function and learning ability.
Article
Clinical Neurology
Wilson A. M. Fisher, Michael P. Catalino, E. Alice Woolard, Bethany J. Andrews, Scott Elton, Carolyn Quinsey
Summary: This study explored the impact of surgical techniques and instruments on the mechanical integrity of ventriculoperitoneal shunt system, specifically shunt catheters. The results showed that the failure rates varied significantly depending on the instruments used and the assembly technique. The use of mosquito forceps with shods and technique A resulted in significantly lower failure rates, while DeBakey forceps were found to be the most damaging instrument.
JOURNAL OF NEUROSURGERY
(2023)
Review
Clinical Neurology
Majid Aljoghaiman, Bradley Bergen, Radwan Takroni, Bill Wang, Paul Eangles, Forough Farrokhyar, Sunjay Sharma
Summary: This review assessed the impact of image guidance on ventricular drain insertion. The results showed that the use of image guidance can improve drain placement accuracy and reduce drain failure rate, but its effect on the number of insertion attempts remains uncertain.
WORLD NEUROSURGERY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Hedieh Khalatbari, Marguerite T. Parisi
Summary: This article discusses the management of hydrocephalus and the high failure rate of CSF shunts used to treat it. Imaging is crucial for assessing shunt failure and determining the need for surgical revision to prevent permanent neurologic damage.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Clinical Neurology
Joyce Koueik, Bermans J. Iskandar, Zhe Yang, Mark R. Kraemer, Stephanie Armstrong, Victor Wakim, Aimee Teo Broman, Joshua Medow, Christopher Luzzio, David A. Hsu
Summary: This study conducted in vitro benchtop analyses of CSF shunt valves under simulated physiological conditions, revealing that lower compliance and higher pulsation generator forces lead to higher pulse pressures and flow rates in the pseudo-ventricle. The presence of a valve mitigates but does not eliminate higher flow rates, indicating the need for further research in developing novel valves to address gravity-dependent overdrainage.
Article
Neurosciences
Giuseppe Emmanuele Umana, Gianluca Scalia, Kaan Yagmurlu, Rosalia Mineo, Simone Di Bella, Matteo Giunta, Angelo Spitaleri, Rosario Maugeri, Francesca Graziano, Marco Fricia, Giovanni Federico Nicoletti, Santino Ottavio Tomasi, Giuseppe Raudino, Bipin Chaurasia, Gianluca Bellocchi, Maurizio Salvati, Domenico Gerardo Iacopino, Salvatore Cicero, Massimiliano Visocchi, Lidia Strigari
Summary: The study introduced a new device for EVD placement and conducted various simulations to test its effectiveness. Results from cadaveric tests and multimodal simulations showed promising outcomes, suggesting the device could offer safer and more effective EVD placement. Further validation in future clinical studies is recommended.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Hyeong Cheol Moon, Sang Joon Park, Young Deok Kim, Kyung Min Kim, Ho Kang, Eun Jung Lee, Min-Sung Kim, Jin Wook Kim, Yong Hwy Kim, Chul-Kee Park, Young Gyu Kim, Yun-Sik Dho
Summary: This study evaluates a new approach to gamma knife radiosurgery using augmented reality technology for frameless fixation navigation. The combination of 3D printing and virtual models allows for precise positioning without the need for CBCT scanning, reducing preparation time for treatment.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Kaushik Sil, Sudip Ghosh, Sandip Chatterjee
Summary: This brief report describes two cases of multiple shunt revisions using the gallbladder as an alternative implantation site for the distal catheter. One case had a long-term functioning shunt, while the other case experienced complications. Relevant literature is also briefly reviewed in this study.
Review
Clinical Neurology
Albert M. Isaacs, Runze Yang, Magalie Cadieux, David Ben-Israel, Nicholas Sader, Michael Opoku-Darko, Leonardo Frizon, Heather Yong, Zahra Premji, Sean Nagel, Mark G. Hamilton
Summary: This systematic review and meta-analysis aimed to investigate the shunt failure rate and etiologies in adult patients with hydrocephalus. The overall shunt failure rate in adults was found to be at least 32% after 2 years. The most common causes of shunt failure in adults were infection and obstruction, with the distal catheter being the most common site of failure.
NEUROSURGICAL FOCUS
(2023)
Article
Clinical Neurology
Grace Y. Lai, Pascal Voyer-Nguyen, Thomas Looi, James M. Drake, Brian W. Hanak
Summary: The new shunt assembly tool developed in this study significantly reduced the time and number of attempts needed to connect a shunt catheter to a valve. Neurosurgeons preferred the new tool over existing instruments and found it easier to use. There was no evidence of catheter damage with the use of this tool.
OPERATIVE NEUROSURGERY
(2021)
Review
Neurosciences
Guillaume Dannhoff, Salvatore Chibbaro, Charles-Henry Mallereau, Mario Ganau, Martial Agbo-Ponzo, Marie des Neiges Santin, Irene Ollivier, Raoul Pop, Francois Proust, Julien Todeschi
Summary: Delayed intracranial hemorrhage (DICH) is a fatal complication that occurs primarily after ventricular drainage procedures. Our study found that DICH cases are often associated with neurovascular disorders, such as rupture of brain arteriovenous malformation (bAVM), emphasizing the significance of underlying pathologies in predisposing to these complications.
Article
Clinical Neurology
Zachary Levin, Owen P. Leary, Victor Mora, Shawn Kant, Sarah Brown, Konstantina Svokos, Umer Akbar, Thomas Serre, Petra Klinge, Alexander Fleischmann, Maria Grazia Ruocco
Summary: By using genome-wide RNA sequencing of cerebrospinal fluid, researchers identified genes and pathways that correlate with improvement in gait, urinary incontinence, and cognitive symptoms after shunt surgery in patients with normal pressure hydrocephalus. They also developed a machine learning algorithm to predict surgical outcomes based on gene expression profiles. These transcriptomic signatures have important implications for improving diagnosis, treatment, and understanding of the disease.
Article
Clinical Neurology
Syed I. I. Khalid, Brittany M. M. Hunter, Pal Shah, Aashka Patel, Kyle B. B. Thomson, Melissa A. A. LoPresti, Douglas W. W. Roblin, Sandi Lam, Ankit I. I. Mehta
Summary: Social risk factors have a negative impact on health outcomes in pediatric shunted hydrocephalus, leading to increased rates of infection, revision, and mortality. Interventions targeting these risk factors are necessary to improve the outcomes of children undergoing CSF diversion.
Article
Clinical Neurology
Michael Bruneau, Julien Spitaels, Matteo Riva
Summary: This study developed a simple surgical technique to reduce ventricular catheter misplacements based on radio-anatomical landmarks. By reproducing preoperative imaging on the patient's head using common anatomical landmarks, stereotactic VC coordinates can be defined for improved accuracy during surgery. This cost-effective method improves VC insertion accuracy.
ACTA NEUROCHIRURGICA
(2021)
Article
Medicine, General & Internal
Shijun Hu, Tao Liu, Shixiong Huang, Hui Liang
Summary: This article reports and discusses a case of cryptococcal meningitis treated with inadequate medical therapy and placement of a ventriculoperitoneal shunt. The patient survived for more than 10 years under these treatments.
FRONTIERS IN MEDICINE
(2022)
Article
Clinical Neurology
Pietro Fiaschi, Corrado Iaccarino, Roberto Stefini, Enrico Prior, Alessandro Prior, Gianluigi Zona
Summary: There is a lack of consensus in managing antiplatelet therapy for neurosurgical patients, impacting patient treatment significantly. The survey reveals a considerable variability in neurosurgical care for patients on antiplatelet therapy, indicating a scarcity of evidence on this issue.
NEUROSURGICAL REVIEW
(2021)
Review
Clinical Neurology
Davide Nasi, Stefano Meletti, Vincenzo Tramontano, Giacomo Pavesi
CLINICAL NEUROLOGY AND NEUROSURGERY
(2020)
Review
Genetics & Heredity
Susanna Rizzi, Carlotta Spagnoli, Grazia Gabriella Salerno, Daniele Frattini, Stefano Giuseppe Caraffi, Gabriele Trimarchi, Claudio Moratti, Rosario Pascarella, Livia Garavelli, Carlo Fusco
AMERICAN JOURNAL OF MEDICAL GENETICS PART A
(2020)
Article
Clinical Neurology
Jessica Rossi, Lucia Giaccherini, Francesco Cavallieri, Manuela Napoli, Claudio Moratti, Elisabetta Froio, Silvia Serra, Alessandro Fraternali, Reza Ghadirpour, Salvatore Cozzi, Patrizia Ciammella, Corrado Laccarino, Rosario Pascarella, Franco Valzania, Anna Pisanello
Article
Genetics & Heredity
Ilenia Maini, Edoardo Errichiello, Stefano Giuseppe Caraffi, Simonetta Rosato, Veronica Bizzarri, Marzia Pollazzon, Gabriele Trimarchi, Gianluca Contro, Benedetta Cavirani, Chiara Gelmini, Manuela Napoli, Claudio Moratti, Rosario Pascarella, Susanna Rizzi, Carlo Fusco, Orsetta Zuffardi, Livia Garavelli
Summary: Basel-Vanagaite-Smirin-Yosef syndrome (BVSYS) is a rare autosomal recessive genetic disorder caused by variants in the MED25 gene, with common features including severe developmental delay and various anomalies. This report presents two sisters with BVSYS, one of whom died at a young age, and whole exome sequencing identified a variant in the MED25 gene.
Article
Clinical Neurology
Andrea Castellucci, Cecilia Botti, Luigi Renna, Silvia Delmonte, Claudio Moratti, Rosario Pascarella, Giovanni Bianchin, Angelo Ghidini
Summary: This case report presents an unusual clinical scenario of otogenic meningitis causing pneumolabyrinth and pneumocephalus in a patient with superior canal dehiscence, resulting in profound sensorineural hearing loss. The case provides insight into the etiology of pneumolabyrinth and conveys the possibility of pneumocephalus being intracranially carried by superior canal dehiscence. Additionally, it demonstrates a unique pattern of functional dissociation among inner-ear receptors, with enhanced otolith function despite severe labyrinthine damage.
OTOLOGY & NEUROTOLOGY
(2021)
Editorial Material
Clinical Neurology
Franco Servadei, Delia Cannizzaro
ACTA NEUROCHIRURGICA
(2021)
Article
Clinical Neurology
Federico Cagnazzo, Michel Piotin, Simon Escalard, Benjamin Maier, Marc Ribo, Manuel Requena, Raoul Pop, Anca Hasiu, Roberto Gasparotti, Dikran Mardighian, Mariangela Piano, Amedeo Cervo, Omer Faruk Eker, Vincent Durous, Nader-Antoine Sourour, Mahmoud Elhorany, Andrea Zini, Luigi Simonetti, Simona Marcheselli, Nuzzi Nunzio Paolo, Emmanuel Houdart, Alexis Guedon, Noemie Ligot, Benjamin Mine, Arturo Consoli, Bertrand Lapergue, Pere Cordona Portela, Xabier Urra, Alejandro Rodriguez, Federico Bolognini, Pablo Ariel Lebedinsky, Anne Pasco-Papon, Sophie Godard, Gaultier Marnat, Igor Sibon, Nicola Limbucci, Patrizia Nencini, Sergio Nappini, Valentina Saia, Valentina Caldiera, Daniele Romano, Giulia Frauenfelder, Ivan Gallesio, Giuliano Gola, Roberto Menozzi, Antonio Genovese, Alberto Terrana, Andrea Giorgianni, Manuel Cappellari, Raffaele Augelli, Paolo Invernizzi, Marco Pavia, Elvis Lafe, Anna Cavallini, Alessia Giossi, Michele Besana, Luca Valvassori, Antonio Macera, Lucio Castellan, Giancarlo Salsano, Fortunato Di Caterino, Alessandra Biondi, Caroline Arquizan, Julien Lebreuche, Gianluca Galvano, Alfio Cannella, Mirco Cosottini, Guido Lazzarotti, Giuseppe Guizzardi, Alessandro Stecco, Rossana Tassi, Sandra Bracco, Elena Bianchini, Camilla Micieli, Rosario Pascarella, Manuela Napoli, Francesco Causin, Hubert Desal, Francois Cotton, Vincent Costalat
Summary: The study found that the 30-day mortality rate after MT in COVID-19 patients was 29%, and abnormalities in lymphocyte count, LDH, and aspartate levels may indicate poorer outcomes. The rate of symptomatic intracranial hemorrhage was 5.4%.
Article
Clinical Neurology
Alessandro Prior, Pietro Fiaschi, Corrado Iaccarino, Roberto Stefini, Denise Battaglini, Alberto Balestrino, Pasquale Anania, Enrico Prior, Gianluigi Zona
Summary: There is a lack of knowledge in the management of neurosurgical patients taking anticoagulant drugs, and it is strongly recommended to establish a hospital-wide policy to address this issue.
Article
Clinical Neurology
Edoardo Picetti, Patrizia Ceccarelli, Laura Malchiodi, Francesca Mensi, Solange Risolo, Franco Servadei, Corrado Iaccarino, Ilaria Rossi, Sandra Rossi
Summary: This study aimed to evaluate the variations in intracranial pressure (ICP) after antipyretic therapy in acute brain injury patients and their relationship to baseline ICP. The results showed that the variation in ICP after antipyretic therapy was influenced by baseline ICP. Specifically, patients with baseline ICP greater than 15 mmHg showed a significant increase in ICP after antipyretic therapy, while a significant reduction in ICP was observed in patients with baseline ICP less than or equal to 15 mmHg.
JOURNAL OF NEUROSURGICAL SCIENCES
(2022)
Editorial Material
Clinical Neurology
Marialuisa Zedde, Claudio Moratti, Manuela Napoli, Franco Valzania, Rosario Pascarella
ACTA NEUROLOGICA BELGICA
(2023)
Article
Clinical Neurology
Katharina Seystahl, Nicolas Martinez-Majander, Alexander Salerno, Morin Beyeler, Hebun Erdur, Joao Pedro Marto, Christian Hametner, Marialuisa Zedde, Alessandro Pezzini, Ronen Leker, Valerian Altersberger, Gianluca Costamagna, Miguel Serodio, Ludovica Migliaccio, Rosario Pascarella, Andrea Zini, Laura Mannismaki, Yannick Bejot, Simon Jung, Henrik Gensicke, Visnja Padjen, Peter A. Ringleb, Christian Nolte, Mirjam R. Heldner, Patrik Michel, Stefan T. Engelter, Sami Curtze, Michael Weller, Susanne Wegener
Summary: This study analyzed data from the European TRISP collaboration to assess the frequency of symptomatic and fatal intracranial hemorrhage (ICH) in patients with intracranial tumors who underwent intravenous thrombolysis (IVT) for suspected ischemic stroke. The results showed a potential high risk of symptomatic ICH in patients with tumors of the pituitary region and suggested that these findings could guide individual treatment decisions in this population.
Article
Clinical Neurology
Carlo Alberto Cesaroni, Daniele Frattini, Marco Lecis, Federico Bonvicini, Domenico Bartolomeo, Susanna Rizzi, Carlotta Spagnoli, Manuela Napoli, Rosario Pascarella, Alessandro De Fanti, Carlo Fusco
Summary: This article reports a case of Tick-Borne Encephalitis in a 6-year-old boy who initially presented with myositis-like symptoms and later developed encephalitic symptoms. Neuroimaging and EEG findings supported the diagnosis of Tick-Borne Encephalitis.
Article
Clinical Neurology
Marialuisa Zedde, Ilaria Grisendi, Federica Assenza, Gabriele Vandelli, Manuela Napoli, Claudio Moratti, Franco Valzania, Rosario Pascarella
Summary: The study presents a rare case of a male patient who developed lacunar ischemic stroke and atypical variant of PRES with chronic small vessel disease markers, as seen in the MRI findings. The association between PRES and ischemic stroke provides insights into the pathomechanisms of PRES.
NEUROLOGICAL SCIENCES
(2023)
Article
Clinical Neurology
Giacomo Pavesi, Davide Nasi, Elisa Moriconi, Riccardo Stanzani, Annette Puzzolante, Lucio Lucchesi, Selene Marika Cavallo, Corrado Iaccarino
Summary: This study retrospectively analyzed the use of intraoperative external ventricular drainage in patients with aneurysmal subarachnoid hemorrhage (aSAH). The results showed that intraoperative external ventricular drainage is a safe technique that facilitates dissection during early surgery.
ACTA NEUROCHIRURGICA
(2022)
Article
Clinical Neurology
Hyunjung Kim, Jhii-Hyun Ahn, Sung Min Ko, Jin Woo Kim
Summary: The pre-navigation balloon technique significantly reduces the occurrence of distal embolism and increases the first-pass effect (FPE) during stent retriever thrombectomy. This technique is particularly effective for patients with ICA occlusion, improving clinical outcomes.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2024)
Review
Clinical Neurology
Mehdi Khaleghi, Joshua Vignolles-Jeong, Bradley Otto, Ricardo Carrau, Daniel Prevedello
Summary: This study presented a rare case of symptomatic ectopic Rathke's cleft cyst (RCC), which was located posterior to the pituitary gland and caused extensive clival erosion. The surgical technique of wide marsupialization of the cyst using intraoperative ultrasound-assisted endoscopic endonasal transclival approach was described, and a systematic literature review of intracranial ectopic RCCs was conducted.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2024)
Article
Clinical Neurology
Oscar H. Del Brutto, Denisse A. Rumbea, Aldo F. Costa, Maitri Patel, Mark J. Sedler, Robertino M. Mera
Summary: This study found an association between cognitive impairment and mortality risk in adults of Amerindian ancestry living in rural Ecuador.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2024)
Article
Clinical Neurology
Yangjingyi Xia, Li Li, Yunze Li, Manyan Hu, Tianrui Zhang, Qinghua Feng, Wenlei Li, Yuan Zhu, Minghua Wu
Summary: This study shows that fasting blood glucose (FBG) level is significantly associated with unfavorable outcome after acute ischemic stroke (AIS) in patients. The risk of unfavorable outcome increases significantly when FBG is above 5.5 mmol/L.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2024)
