Article
Oncology
Gui-Min Wen, Chang-Liang Song, Da-Hua Liu, Pu Xia
Summary: Different ethnic groups have different incidence rate of hepatocellular carcinoma (HCC) due to lifestyle, environmental factors, and genetic susceptibility. This study used the ESTIMATE algorithm to screen immune related genes and stromal related genes in White and Asian liver cancer patients. Hub genes significantly associated with overall survival (OS) were selected separately from White and Asian liver cancer patients. In addition, the functions of two hub genes, IL-18RAP and GPM6A, were validated in vivo and in vitro. The study confirms the presence of different tumor immune microenvironments among races, which can influence the efficacy of immunotherapy for liver cancer patients.
AMERICAN JOURNAL OF CANCER RESEARCH
(2023)
Article
Oncology
Elena Torralba-Martinez, Maria Jesus Quintana, Magda Ciendones Carbonell, Elena de Las Sias, Cristian Pablo Segura Carrillo, Nuria Codern-Bove
Summary: The study found that coping strategies for women with breast cancer evolve according to the meaning of the disease in different phases, as well as age and family income. Different age groups and income levels of women use different coping strategies at different stages, with social support playing a significant role in each phase.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Mu Xie, Xian-Shu Gao, Ming-Wei Ma, Xiao-Bin Gu, Hong-Zhen Li, Feng Lyu, Yun Bai, Jia-Yan Chen, Xue-Ying Ren, Ming-Zhu Liu
Summary: In this study, the NCCN-g and AUA-g risk stratification systems showed better discrimination ability in predicting prostate cancer-specific mortality compared to the EAU-g system. Specifically, the discrimination ability of the NCCN-g system was found to be superior to that of the AUA-g system.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Naomi Y. Ko, Tsion G. Fikre, Anne K. Buck, Emily Restrepo, Erica T. Warner
Summary: Black breast cancer survivors have specific needs, challenges, and preferences. Supportive interventions that address their concerns are responsive and can help to ameliorate disparities.
Article
Oncology
Sumit Gupta, Rinku Sutradhar, Priscila Pequeno, Johann K. Hitzler, Ning Liu, Paul C. Nathan
Summary: Children with leukemia and Down syndrome (DS) have a higher risk of acute treatment toxicities and late mortality compared to those without DS. DS survivors experienced inferior overall survival compared to non-DS survivors and DS controls. Chronic morbidities associated with DS were not increased compared to DS controls.
Article
Oncology
Ursula M. Sansom-Daly, Claire E. Wakefield, Christina Signorelli, Mark W. Donoghoe, Antoinette Anazodo, Susan M. Sawyer, Michael Osborn, Rosalie Viney, Nicholas Daniell, Kate Faasse, Richard J. Cohn
Summary: Adolescent and young adult cancer survivors face significant physical/mental health late effects following cancer treatment, which can be minimized through tailored healthcare use. A cross-sectional study found that cancer survivors reported greater use of medical and mental health services, particularly females, those diagnosed with brain/solid tumors, and those more recently finished treatment. Further research is needed to determine if the healthcare accessed by these survivors is appropriate and meets their needs.
Article
Oncology
Morhaf Al Achkar, Upal Basu Roy, Eugene Manley, Maisha Standifer, Christina Baik, Casey A. Walsh
Summary: This study aimed to understand the perspectives of advanced lung cancer patients with oncogenic alterations about their care experiences with oncologists and describe their perceptions on seeking second opinions and making care decisions. The results showed that patients value interactions that support their autonomy, demonstrate provider competency, and foster connectedness.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Chelsea Anderson, Anne F. Peery, Victoria L. Bae-Jump, Wendy R. Brewster, Jennifer L. Lund, Andrew F. Olshan, Hazel B. Nichols
Summary: In this study, we investigated the risk of gastrointestinal diagnoses among older women with endometrial cancer. The results showed that women with endometrial cancer had an increased risk of gastrointestinal symptoms after diagnosis, including constipation, abdominal pain, and fecal incontinence. It is important to provide surveillance for these conditions in the care of endometrial cancer survivors.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Melanie Turner, Romi Carriere, Shona Fielding, George Ramsay, Leslie Samuel, Andrew Maclaren, Peter Murchie
Summary: Limited data exist on the effect of travelling time on post-diagnosis cancer care and mortality. This study analyzed the impact of travel time to cancer treatment center on secondary care contact time and one-year mortality in Scotland. Patients with longer travelling time and island-dwellers had increased secondary care cancer contact time. Longer travel time was not associated with increased secondary care contact time for emergency cancer admissions. Living on an island increased mortality at one-year.
Article
Oncology
Justin M. Barnes, Kimberly J. Johnson, Jeremy L. Grove, Amar J. Srivastava, Nosayaba Osazuwa-Peters, Stephanie M. Perkins
Summary: The study found that long-term childhood cancer survivors may have an increased risk of suicide, especially among survivors over the age of 28. Male gender is associated with a higher risk of suicide compared to females. Among the selected childhood cancer patients, the risk of suicide is similar to those without a history of cancer.
Article
Oncology
J. J. Adashek, A. Jordan, L. S. Redwine, D. Martinez Tyson, Z. Thompson, S. Pabbathi
Summary: The study indicates that most cancer survivors had clinical needs relating to Fear of Cancer Recurrence (FCR) at the time of survey, but these needs were met. Patients with higher distress scores were more likely to report FCR as an unmet need.
Article
Oncology
Kain Phansuwon, Sim Yee (Cindy)Tan, Kim Kerin-Ayres, Ashanya Malalasekera, Janette L. Vardy
Summary: The study found that while most survivors found SCP useful, they did not share them with other healthcare providers, raising questions about their effectiveness in coordinating care. Additionally, there were challenges with SCP delivery. Survivors reported compliance with SCP lifestyle recommendations. Further research is needed to assess the utility of SCP among other stakeholders such as general practitioners.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Chemistry, Analytical
Jing Fang, Xiangying Sheng, Huimin Bao, Ying Zhang, Haojie Lu
Summary: Breast cancer is a highly heterogeneous disease with different subtypes showing distinct biological characteristics and behaviors. This study identified multiple glycosylation sites and glycan types of mannose receptors in breast cancer patients' serum, some of which can be used to differentiate the subtypes of breast cancer.
Article
Oncology
Edward Christopher Dee, Ryan D. Nipp, Vinayak Muralidhar, Zizi Yu, Santino S. Butler, Brandon A. Mahal, Paul L. Nguyen, Nina N. Sanford
Summary: A majority of cancer survivors reported financial worry, with female sex, younger age, and Asian American race associated with increased odds of financial worry. Participants endorsing financial worry were more likely to have psychological distress.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Medicine, General & Internal
Daoliang Wang, Liang Yi, Lijun Zhang, Zhuo Wang
Summary: The study aimed to investigate mortality patterns and prognostic risks for cause-specific death among T1-2N0M0 breast cancer survivors, using data from the Surveillance, Epidemiology, and End Results program. The findings showed specific mortality ratios and identified prognostic factors for breast cancer-specific and CVD-specific mortality. The study supports early detection and improved CVD care for these patients.
