Journal
CLINICAL LIPIDOLOGY
Volume 5, Issue 3, Pages 329-337Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/CLP.10.20
Keywords
dyslipidemia; intima-media thickness; lipoprotein; reverse cholesterol transport; small dense LDL
Categories
Funding
- Regional Health Trust-University
Ask authors/readers for more resources
The term 'dyslipidemia' includes a wide family of lipoprotein metabolic defects often related to cardiovascular diseases. Despite the complexity of lipid disorders, current guidelines indicate LDL-C as the single most important therapeutic target; however, other lipido-proteic parameters, such as the concentration of lipoprotein subfractions (e.g., small-dense LDL) or their functional capacity (e.g., HDL reverse cholesterol transport), may display direct pro- or anti-atherogenic properties. Traditional lipid profiles may therefore be inadequate in representing dyslipidemia complexity and may prove to be ineffective in estimating the overall patient's risk in this context. We designed a research project attempting to provide a coherent framework integrating traditional lipid profiling and advanced diagnostics, to assess qualitative and functional lipoprotein features in relevant clinical conditions and to correlate them with preclinical atherosclerosis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available