Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 39, Pages 11453-11456Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201505733
Keywords
cation-pi interactions; copper; luminescence; peptides; terbium
Categories
Funding
- Agence Nationale de la Recherche [ANR-12-BS07-0012-01]
- Labex ARCANE [ANR-11-LABX-0003-01]
Ask authors/readers for more resources
A prototype luminescent turn-on probe for Cu+ (and Ag+) is described, harnessing a selective binding site (log K-ass = 9.4 and 7.3 for Cu+ and Ag+, respectively) based on the coordinating environment of the bacterial metallo-chaperone CusF, integrated with a terbium-ion-signaling moiety. Cation-pi interactions were shown to enhance tryptophan triplet population, which subsequently sensitized, on the microsecond timescale, the long-lived terbium emission, offering a novel approach in bioinspired chemosensor design.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available