Article
Transplantation
Erandi Hewawasam, Christopher E. Davies, Aarti Gulyani, Zhuoyang Li, Philip A. Clayton, Elizabeth Sullivan, Stephen P. McDonald, Shilpanjali Jesudason
Summary: Pregnancy in women receiving kidney replacement therapy (KRT) is uncommon, with transplanted women having higher fertility rates than dialysed women. The fertility rates for dialysed women have been increasing in recent years. Factors such as treatment modality, ethnicity, diabetes, pre-conception eGFR, transplant-to-pregnancy interval, and duration of KRT exposure are associated with fertility rates.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Immunology
Brian Percy Doucet, Yeoungjee Cho, Scott Bryan Campbell, David Wayne Johnson, Carmel Mary Hawley, Armando Rogerio Martins Teixeira-Pinto, Nicole Maree Isbel
Summary: This study in Australia and New Zealand found that elderly kidney transplant recipients had lower survival rates compared to younger recipients and often received lower quality kidneys. Despite these challenges, outcomes for elderly recipients were generally encouraging, suggesting a need to focus on improving outcomes for this population.
TRANSPLANTATION PROCEEDINGS
(2021)
Article
Urology & Nephrology
Hicham I. Cheikh Hassan, Karumathil Murali, Maureen Lonergan, Neil Boudville, David Johnson, Monique Borlace, Jenny H. C. Chen
Summary: This study found that peritonitis is associated with an increased risk of cardiovascular mortality, and the association is dependent on the number of peritonitis episodes. Prevention and adequate treatment of PD peritonitis may improve cardiovascular outcomes among patients receiving PD.
KIDNEY INTERNATIONAL REPORTS
(2022)
Article
Transplantation
Isabelle Ethier, Yeoungjee Cho, Carmel Hawley, Elaine M. Pascoe, Matthew A. Roberts, David Semple, Annie-Claire Nadeau-Fredette, Germaine Wong, Wai H. Lim, Matthew P. Sypek, Andrea K. Viecelli, Scott Campbell, Carolyn van Eps, Nicole M. Isbel, David W. Johnson
Summary: The study compared the survival outcomes of HHD patients and kidney transplant recipients, finding that living donor and standard criteria donor recipients had reduced risks of mortality compared to HHD patients, while the risk of mortality was comparable between expanded criteria donor recipients and HHD patients.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Multidisciplinary Sciences
Juan Pei, Yeoungjee Cho, Yong Pey See, Elaine M. Pascoe, Andrea K. Viecelli, Ross S. Francis, Carolyn van Eps, Nicole M. Isbel, Scott B. Campbell, Philip A. Clayton, Jeremy Chapman, Michael Collins, Wai Lim, Wen Tang, Germaine Wong, Carmel M. Hawley, David W. Johnson
Summary: An observational study in Australia and New Zealand found that acute kidney injury (AKI) in deceased donors did not significantly affect kidney transplant outcomes, except for a potential increased risk of delayed graft function (DGF). This suggests that using kidneys from donors with AKI for transplantation may be justified.
Article
Urology & Nephrology
Weizhen Xie, Li Qin, Jiaying Huang, Aiping Gu, Wei Fang, Na Jiang, Jiangzi Yuan
Summary: This study investigated the clinical risk factors for peritoneal dialysis (PD) withdrawal at different dialysis duration. The results showed that patients who maintained PD for longer than 10 years were younger, had lower prevalence of diabetes, better nutrition status, absence of inflammation, better residual kidney function, and higher proportion of renin-angiotensin system inhibitors (RASi) usage at baseline. Absence of inflammation and use of RASi were independently associated with long-term PD maintenance.
Article
Urology & Nephrology
Jenny H. C. Chen, David W. Johnson, Germaine Wong, Neil Boudville, Monique Borlace, Rachael Walker, Carmel Hawley, Stephen McDonald, Wai H. Lim
Summary: This study found that peritoneal dialysis patients with diabetic nephropathy had increased risk of PD technique failure and mortality, with these risks being greater in women.
PERITONEAL DIALYSIS INTERNATIONAL
(2021)
Article
Urology & Nephrology
Benjamin Talbot, Katherine Barraclough, Matthew Sypek, Pedro Gois, Leila Arnold, Stephen McDonald, John Knight
Summary: This study investigated the environmental sustainability practices of dialysis facilities in Australia and New Zealand. The findings showed a lack of prioritization of environmental sustainability in clinical practice, building design and infrastructure, and management systems.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Transplantation
Eric Goffin, Alexandre Candellier, Priya Vart, Marlies Noordzij, Miha Arnol, Adrian Covic, Paolo Lentini, Shafi Malik, Louis J. Reichert, Mehmet S. Sever, Bruno Watschinger, Kitty J. Jager, Ron T. Gansevoort
Summary: This study found that kidney transplant recipients have a higher risk of developing a more severe course of COVID-19 compared to hemodialysis patients, especially within the first year post-transplant. Therefore, specific infection mitigation strategies are needed for this group of patients.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Urology & Nephrology
Tahira Scott, Isabelle Ethier, Carmel Hawley, Elaine M. Pascoe, Andrea K. Viecelli, Arnold Ng, Yeoungjee Cho, David W. Johnson
Summary: The study revealed that patients with kidney failure from atheroembolic disease have worse survival rates on dialysis compared to those with other causes of kidney failure. This could be attributed to patient demographics and higher comorbidity.
Article
Urology & Nephrology
Isabelle Ethier, Scott B. Campbell, Yeoungjee Cho, Carmel M. Hawley, Nicole M. Isbel, Rathika Krishnasamy, Matthew A. Roberts, David Semple, Matthew Sypek, Andrea K. Viecelli, David W. Johnson
Summary: This study aimed to explore the association between dialysis modality utilization patterns and outcomes in older persons. The results showed that the utilization patterns of different dialysis modalities were associated with mortality in older persons.
Article
Nutrition & Dietetics
Marille Umakanthan, John Wing Li, Kamal Sud, Gustavo Duque, Daniel Guilfoyle, Kenneth Cho, Chris Brown, Derek Boersma, Muralikrishna Gangadharan Komala
Summary: The prevalence of sarcopenia in Australian maintenance dialysis patients was found to be 18%, with low serum albumin and phosphate levels identified as significant risk factors. Increasing age and female sex were also potential risk factors. Low lean muscle mass, reduced hand grip strength, and prolonged TUG were common within the cohort, with hand grip test showing good correlation with lean muscle evaluation and TUG.
Article
Transplantation
Victor Khou, Nicole L. De la Mata, Rachael L. Morton, Patrick J. Kelly, Angela C. Webster
Summary: Withdrawal from renal replacement therapy is common in patients with end-stage kidney disease, and in Australia and New Zealand, the mortality rates related to treatment withdrawal have been increasing, particularly from 1995 to 2013. A significant proportion of withdrawal deaths occur within 12 months of treatment modality change, with kidney failure being a common underlying cause of death.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Respiratory System
Katherine Kearney, Joshua Gold, Carolyn Corrigan, Kumud Dhital, David Boshell, David Haydock, David McGiffin, Michael Wilson, Nicholas Collins, Rachael Cordina, Nathan Dwyer, John Feenstra, Melanie Lavender, Jeremy Wrobel, Helen Whitford, Trevor Williams, Dominic Keating, Ken Whyte, Tanya McWilliams, Anne Keogh, Geoff Strange, Eugene Kotlyar, James Anderson, Edmund M. T. Lau
Summary: This study aimed to describe the clinical characteristics, treatment strategies, and long-term survival rates of patients with CTEPH in Australia and New Zealand. The study found that only 37.8% of patients underwent PEA surgery, and the long-term survival rates were comparable to other CTEPH registries.
Article
Medicine, General & Internal
Shantelle Smith, Margaret Brand, Susan Harden, Lisa Briggs, Lillian Leigh, Fraser Brims, Mark Brooke, Vanessa N. Brunelli, Collin Chia, Paul Dawkins, Ross Lawrenson, Mary Duffy, Sue Evans, Tracy Leong, Henry Marshall, Dainik Patel, Nick Pavlakis, Jennifer Philip, Nicole Rankin, Nimit Singhal, Emily Stone, Rebecca Tay, Shalini Vinod, Morgan Windsor, Gavin M. Wright, David Leong, John Zalcberg, Rob G. Stirling
Summary: The Australia and New Zealand Lung Cancer Registry (ANZLCR) is established to monitor the safety, quality, and effectiveness of lung cancer care in Australia and New Zealand. Electronic data collection and data linkage are used to enhance completeness and accuracy of the data. The findings will be reported to participating sites and stakeholders, and online dashboard indicator reporting will be used to facilitate quality improvement efforts.
Article
Medicine, General & Internal
Sradha Kotwal, Alan Cass, Sarah Coggan, Nicholas A. Gray, Stephen Jan, Stephen McDonald, Kevan R. Polkinghorne, Kris Rogers, Girish Talaulikar, Gian Luca Di Tanna, Martin Gallagher
Summary: This study indicates that implementing multifaceted interventions did not reduce the rate of CRBSI among patients requiring hemodialysis catheters. Therefore, multifaceted interventions to prevent CRBSI may not be effective in clinical practice settings.
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Article
Health Policy & Services
Dharmenaan Palamuthusingam, Elaine M. Pascoe, Carmel M. Hawley, David W. Johnson, Gishan Ratnayake, Stephen McDonald, Neil Boudville, Matthew Jose, Magid Fahim
Summary: This study assessed the concordance between comorbidities recorded in the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry and those in state-based hospital admission datasets. The results showed that the accuracy of diabetes mellitus recording was the highest, while the accuracy of cerebrovascular disease recording was the lowest.
HEALTH INFORMATION MANAGEMENT JOURNAL
(2023)
Biographical-Item
Medicine, General & Internal
Philip Clayton, Simon Lennane
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Article
Orthopedics
Ian A. Harris, Michelle F. Lorimer, Christopher E. Davies, Dominic Keuskamp, Kathryn B. Dansie, Peter L. Lewis, Stephen E. Graves, Stephen P. McDonald
Summary: This study compared the rate of revision surgery and mortality following THA between patients who have kidney failure receiving long term dialysis or who had a kidney transplant and those who did not have kidney failure. The results showed that patients on dialysis had a higher risk of mortality after THA compared to those with a functioning kidney transplant or no kidney failure, but there was no early excess mortality due to the surgery.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Urology & Nephrology
Ryan Gately, Elasma Milanzi, Wai Lim, Armando Teixeira-Pinto, Phil Clayton, Nicole Isbel, David W. Johnson, Carmel Hawley, Scott Campbell, Germaine Wong
Summary: BK polyomavirus-associated nephropathy (BKPyVAN) is associated with an increased risk of graft dysfunction and loss in kidney transplant recipients. This cohort study in Australia and New Zealand found that BKPyVAN occurred in 3% of recipients and was linked to higher rates of graft loss, rejection, and death. Changes in immunosuppression, such as reducing tacrolimus and mycophenolate doses, were commonly made after BKPyVAN. Several factors, including gender, age, blood group, donor characteristics, transplantation era, immunosuppression use, and transplant center volume, were associated with the development of BKPyVAN. The study also found that BKPyVAN increased the risk of graft loss but not mortality. It highlights the need for interventional trials to evaluate strategies for reducing immunosuppression and minimizing adverse outcomes associated with BKPyVAN.
KIDNEY INTERNATIONAL REPORTS
(2023)
Article
Ethics
Alison C. Weightman, Simon Coghlan, Philip A. Clayton
Summary: The refusal of doctors to accept donations from living kidney donors with certain comorbidities is unjustified according to this paper. The paper argues for greater acceptance of such donations to address the ongoing shortage of kidney transplants.
MONASH BIOETHICS REVIEW
(2023)
Article
Urology & Nephrology
Joe Lu, Erandi Hewawasam, Christopher E. Davies, Philip A. Clayton, Stephen P. McDonald, Shilpanjali Jesudason
Summary: This study aimed to determine the rates of preeclampsia in women with kidney transplants and its association with graft survival and function. The results showed that while preeclampsia is common in women with transplanted kidneys, it is not associated with worse graft survival or function.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Urology & Nephrology
Georgina L. Irish, Laura Cuthbertson, Alex Kitsos, Tim Saunder, Philip A. Clayton, Matthew D. Jose
Summary: This study externally validated the Tangri et al Kidney Failure Risk Equation (KFRE) in an Australian population, and found that the KFRE performs well in predicting progression to kidney failure. The KFRE can be used by clinicians and service planners for individualized risk prediction.
Editorial Material
Medicine, General & Internal
Katie Cundale, Stephen P. Mcdonald, Ashley Irish, Matthew D. Jose, Jillian Diack, Matilda D'Antoine, Kelli J. Owen, Jaquelyne T. Hughes
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Editorial Material
Urology & Nephrology
Stephen P. Mcdonald, Katie Cundale, Kelli J. Owen, Matilda D'Antoine, Jaquelyne T. Hughes
Summary: Indigenous people in Australia are disadvantaged in accessing kidney transplantation. The National Indigenous Kidney Transplant Taskforce was established to address this issue by providing support to clinicians, implementing and evaluating innovative practices, and developing strategies to overcome barriers in the care system.
NATURE REVIEWS NEPHROLOGY
(2023)
Article
Biology
Ken-Soon Tan, Stephen McDonald, Wendy Hoy
Summary: This study compared the performance of a clinical diagnosis to biopsy-proven diagnosis of diabetic kidney disease (DKD) and found that a clinical diagnosis has high sensitivity but low specificity, indicating the possibility of overdiagnosis.
Letter
Urology & Nephrology
Richard Le Leu, Paul N. Bennett, Kathryn Dansie, Lisa Shanahan, Anna Chur-Hansen, Kathryn L. Collins, Anne L. J. Burke, Fiona Donnelly, Emily Duncanson, Anthony Meade, Stephen McDonald, Shilpanjali Jesudason
JOURNAL OF NEPHROLOGY
(2023)
Review
Public, Environmental & Occupational Health
Imogen Jones, Fiona Cocker, Matthew Jose, Michael Charleston, Amanda L. Neil
Summary: The aim of this scoping review is to summarize the techniques used for network analysis of multimorbidity and provide recommendations for a standardized methodology. The results show a lack of recommended standard methods for calculating and displaying networks in multimorbidity. There is also a need for greater detail and transparency in reporting the methodology and software used. Further investigation is required to determine the most appropriate measure of association for network analysis in multimorbidity.
JOURNAL OF PUBLIC HEALTH-HEIDELBERG
(2023)
Meeting Abstract
Urology & Nephrology
Dharmenaan Palamuthusingam, Carmel M. Hawley, Elaine M. Pascoe, Davidw Johnson, Palvannan Sivalingam, Stephen Mcdonald, Neil Boudville, Matthew Jose, Girish Talaulikar, Nick Cross, Magid Fahim