Review
Infectious Diseases
Erfan Banisefid, Kosar Baghernezhad, Rasa Beheshti, Sina Hamzehzadeh, Soheil Nemati, Zahra Samadifar, Hamid Owaysee Osquee, Elnaz Javanshir, Amirreza Naseri
Summary: Cardiac involvement is a rare but serious manifestation of Echinococcus infection, presenting with non-specific signs and symptoms such as dyspnea, chest pain, and palpitation. Timely diagnosis and appropriate management can reduce mortality rates.
BMC INFECTIOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Elham Hassanzadeh, Shahram Khademvatan, Behzad Jafari, Abbas Jafari, Elham Yousefi
Summary: We investigated the scolicidal effects of sanguinarine on hydatid cyst protoscoleces in vitro and in silico. Molecular docking revealed that acetylcholinesterase is a potential target for sanguinarine. Our results demonstrated that sanguinarine has potent scolicidal effects and could be a promising therapeutic agent for treating cystic echinococcosis. Further clinical studies are needed to confirm these findings.
Editorial Material
Cardiac & Cardiovascular Systems
Ayse Ulusoy, Cansel Atinkaya Baytemir, Murat Kavas, Sumeyye Alparslan Bekir, Elcin Ersoz, Sipan Bilek, Irfan Yalconkaya
Summary: This article reports a case of giant lung hydatid cyst in a pediatric patient and describes the treatment method of partial capitonnage using video-assisted thoracoscopic surgery and fibrin glue.
ANNALS OF THORACIC SURGERY
(2022)
Article
Microbiology
Sibo Wang, Haohao Sun, Shan Wang, Qian Ren, Yi Dai, Meipeng Zhu, Yayun Zhang, Honglei Kang, Jing Li, Jun Xiao, Yimin Dong, Weishan Wang
Summary: Spinal cystic echinococcosis is a severely neglected, rare disease with high morbidity, disability, and mortality in prevalent regions. This study examined the therapeutic effects of a-mangostin for spinal cystic echinococcosis and explored its potential pharmacological mechanism.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2023)
Article
Parasitology
Xuhui Zhang, Lamu Suolang, Yelei Ren, Yifei Wang, Yong Jiang, Xiaofei Zhong, Zehui Gou, Wu Zhou, Juan Chen, Yongzhong Li, Diming Cai
Summary: In this study, contrast-enhanced ultrasound (CEUS) was found to be more accurate than conventional ultrasound (US) in differentiating between cystic echinococcosis (CE) and alveolar echinococcosis (AE) in the liver. The accuracy rate for CEUS was 91.3%, while for US it was 65.2%. Therefore, CEUS can be considered a reliable tool for the differentiation of hepatic echinococcosis.
PARASITES & VECTORS
(2023)
Review
Pathology
Bentolhoda Habibi, Shirzad Gholami, Abouzar Bagheri, Mahdi Fakhar, Alimohammad Moradi, Mohammad Amin Khazeei Tabari
Summary: Echinococcosis, a zoonotic foodborne disease caused by infection with Echinococcus spp. larvae, poses a challenge in diagnosis due to limited diagnostic tools. Recent studies have identified specific miRNAs in Echinococcus spp. that can be detected in biofluids of infected hosts and serve as early prognostic and diagnostic biomarkers for echinococcosis.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2023)
Article
Medical Informatics
Yongfeng Yang, Yangdan Cairang, Tian'an Jiang, Jianhua Zhou, Li Zhang, Baowen Qi, Shumei Ma, Lina Tang, Dong Xu, Lingdai Bu, Rui Bu, Xiang Jing, Hui Wang, Zubang Zhou, Cheng Zhao, Baoming Luo, Liwen Liu, Jianqin Guo, Yuzhen Nima, Guoyong Hua, Zengcheng Wa, Yuying Zhang, Guoyi Zhou, Wen Jiang, Changcheng Wang, Yang De, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Fangyi Liu, Jianping Dou, Hui Feng, Chong Wu, Ruifang Wang, Jie Hu, Qi Yang, Yanchun Luo, Jiapeng Wu, Haining Fan, Ping Liang, Jie Yu
Summary: This study aimed to develop a deep convolutional neural network (DCNN) model based on ultrasonography to identify and classify liver lesions, including echinococcosis. The results showed that the DCNN model demonstrated high accuracy and robustness in diagnosing echinococcosis and its types.
LANCET DIGITAL HEALTH
(2023)
Review
Infectious Diseases
Mar Siles-Lucas, Leonardo Uchiumi, Francesca Tamarozzi
Summary: In this review, the authors provide an update on the diagnosis of cystic echinococcosis. They highlight the accuracy and reliability of ultrasound in depicting the characteristic signs of the disease compared to other imaging techniques. The review also emphasizes the need for univocal case definitions and consensus diagnostic algorithms for cystic echinococcosis.
CURRENT OPINION IN INFECTIOUS DISEASES
(2023)
Article
Gastroenterology & Hepatology
Yosef Sharifi, Seyed Mahmoud Sadjjadi, Hamed Nikoupour Dailami, Seyed Hamed Jafari, Mohammad Hossein Anbardar, Mohammad Bagher Khosravi
Summary: This study reported the first case of HIV coinfection with liver hydatid cyst in Iran, where the patient underwent successful cyst removal surgery. Findings suggest that in cases of HIV coinfection with hydatid cyst, surgery is preferable to other treatment options.
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Parasitology
Eylem Akdur Ozturk, Raul Manzano-Roman, Carlos Sanchez-Ovejero, Ayse Caner, Mesude Angin, Cumhur Gunduz, Ulku Karaman, Nuray Altintas, Halil Bozkaya, Omer Unalp, Zafer Dokumcu, Emre Divarci, Adriano Casulli, Nazmiye Altintas, Mar Siles-Lucas, Aysegul Unver
Summary: The study compared the diagnostic value between Hydatid Fluid (HF) and the multi-epitope antigen DIPOL in IgG-ELISA for Cystic Echinococcoses (CE) patients. Results showed that DIPOL had higher specificity than HF and varying sensitivity depending on cyst stage.
Article
Radiology, Nuclear Medicine & Medical Imaging
Veysel Kaya, Mehmet Tahtabasi, Osman Konukoglu, Metin Yalcin
Summary: The efficacy and safety of percutaneous treatment for CE1 and CE3a giant cysts were investigated, and the management of complications, especially cystobiliary fistulas, was evaluated. The results showed that percutaneous drainage and/or endoscopic retrograde cholangiopancreatography can effectively and safely treat these patients with high clinical success rates.
ACADEMIC RADIOLOGY
(2023)
Article
Veterinary Sciences
Davide De Biase, Francesco Prisco, Paola Pepe, Antonio Bosco, Giuseppe Piegari, Ilaria d'Aquino, Valeria Russo, Serenella Papparella, Maria Paola Maurelli, Laura Rinaldi, Orlando Paciello
Summary: This study examined the inflammatory phenotype of sheep livers infected with cystic echinococcosis through macroscopic assessment, histopathological analysis, and molecular analysis. The livers were classified into three groups: normal liver, liver with fertile hydatid cysts, and liver with sterile hydatid cysts. The results showed that macrophages play a predominant role in the immune response to cystic echinococcosis, with a dominance of Th2 immunity and an immunomodulatory role of IL-10 and TGF-beta.
VETERINARY SCIENCES
(2023)
Article
Medicine, General & Internal
Banwari Lal Bairwa, Ayush Anand
Summary: The proper management of hydatid disease is crucial to prevent mortality. Open surgery is the recommended treatment for multiple and large liver hydatid cysts, and it can lead to a cure. Regular follow-up is also necessary to detect any recurrence.
CLINICAL CASE REPORTS
(2023)
Article
Surgery
Atef Mejri, Khaoula Arfaoui, Mohamed Firas Ayadi, Badreddine Aloui, Jasser Yaakoubi
Summary: This study described the clinical features of isolated primitive splenic hydatid cysts and compared different surgical approaches, finding that total splenectomy may be the safest option to avoid postoperative complications and reduce hospital stay.
Article
Parasitology
Tian Ma, Qian Wang, Mengmeng Hao, Chuizhao Xue, Xu Wang, Shuai Han, Qian Wang, Jiangshan Zhao, Xiao Ma, Xianglin Wu, Xiaofeng Jiang, Lei Cao, Yaming Yang, Yu Feng, Quzhen Gongsang, Juergen Scheffran, Liqun Fang, Richard James Maude, Canjun Zheng, Fangyu Ding, Weiping Wu, Dong Jiang
Summary: This study used the national echinococcosis survey data from 2012 to 2016 to investigate the spatial prevalence, demographic characteristics, and risk factors of cystic and alveolar echinococcosis in China. The results showed that female gender, older age, occupation as a herdsman or religious worker, and illiteracy were identified as risk factors for both types of echinococcosis. The prevalence of the diseases varied geographically, with high endemicity observed in the Tibetan Plateau region. Various environmental, biological, and social factors were found to be associated with the diseases. The findings will contribute to the development of targeted prevention measures and disease control strategies.
PARASITES & VECTORS
(2023)