Effective Utilization of Evolving Methods for the Laboratory Diagnosis of Clostridium difficile Infection

Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)

(2010) Stuart H. Cohen et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Clostridium difficileTesting in the Clinical Laboratory by Use of Multiple Testing Algorithms

(2010) Susan M. Novak-Weekley et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of the C.Diff Quik Chek Complete Assay, a New Glutamate Dehydrogenase and A/B Toxin Combination Lateral Flow Assay for Use in Rapid, Simple Diagnosis of Clostridium difficile Disease

(2010) S. E. Sharp et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of Two Commercial Molecular Assays to a Laboratory-Developed Molecular Assay for Diagnosis of Clostridium difficile Infection

(2010) T. Karre et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Point-Counterpoint: What Is the Current Role of Algorithmic Approaches for Diagnosis ofClostridium difficileInfection?

(2010)   JOURNAL OF CLINICAL MICROBIOLOGY

Impact of Strain Type on Detection of Toxigenic Clostridium difficile: Comparison of Molecular Diagnostic and Enzyme Immunoassay Approaches

(2010) F. C. Tenover et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The role of toxin A and toxin B in Clostridium difficile infection

(2010) Sarah A. Kuehne et al.   NATURE

Clostridium difficile testing algorithms: What is practical and feasible?

(2009) Monica L. Schmidt et al.   ANAEROBE

Clinical and microbiological characteristics of community-onset Clostridium difficile infection in The Netherlands

(2009) M.P. Bauer et al.   CLINICAL MICROBIOLOGY AND INFECTION

Comparison of BD GeneOhm Cdiff Real-Time PCR Assay with a Two-Step Algorithm and a Toxin A/B Enzyme-Linked Immunosorbent Assay for Diagnosis of ToxigenicClostridium difficileInfection

(2009) Elizabeth J. Kvach et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of Nine Commercially Available Clostridium difficile Toxin Detection Assays, a Real-Time PCR Assay for C. difficile tcdB, and a Glutamate Dehydrogenase Detection Assay to Cytotoxin Testing and Cytotoxigenic Culture Methods

(2009) K. Eastwood et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation of Diagnostic Tests for Clostridium difficile Infection

(2009) J. Swindells et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of a Commercial Multiplex Real-Time PCR to the Cell Cytotoxicity Neutralization Assay for Diagnosis of Clostridium difficile Infections

(2009) H. Huang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Evaluation oftcdBReal-Time PCR in a Three-Step Diagnostic Algorithm for Detection of ToxigenicClostridium difficile

(2009) Ann M. Larson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Algorithm Combining Toxin Immunoassay and Stool Culture for Diagnosis of Clostridium difficile Infection

(2009) B.-M. Shin et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Antimicrobial‐Associated Risk Factors forClostridium difficileInfection

(2008) Robert C. Owens et al.   CLINICAL INFECTIOUS DISEASES

Clinical Recognition and Diagnosis ofClostridium difficileInfection

(2008) John G. Bartlett et al.   CLINICAL INFECTIOUS DISEASES

Repeated enzyme immunoassays have limited utility in diagnosing Clostridium difficile

(2008) M. Drees et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Review of Current Literature on the Economic Burden of Clostridium difficile Infection

(2008) Erik R. Dubberke et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Nonutility of Repeat Laboratory Testing for Detection of Clostridium difficile by Use of PCR or Enzyme Immunoassay

(2008) E. Aichinger et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of Real-Time PCR for Detection of the tcdC Gene with Four Toxin Immunoassays and Culture in Diagnosis of Clostridium difficile Infection

(2008) L. M. Sloan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparison of a Commercial Real-Time PCR Assay for tcdB Detection to a Cell Culture Cytotoxicity Assay and Toxigenic Culture for Direct Detection of Toxin-Producing Clostridium difficile in Clinical Samples

(2008) P. D. Stamper et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Is a Two-Step Glutamate Dehyrogenase Antigen-Cytotoxicity Neutralization Assay Algorithm Superior to the Premier Toxin A and B Enzyme Immunoassay for Laboratory Detection of Clostridium difficile?

(2008) P. H. Gilligan   JOURNAL OF CLINICAL MICROBIOLOGY

Diagnosis of Clostridium difficile infection by toxin detection kits: a systematic review

(2008) Tim Planche et al.   LANCET INFECTIOUS DISEASES