Article
Clinical Neurology
Joga Chaganti, Michael Taylor, Hannah Woodford, Timothy Steel
Summary: The study demonstrated significant differences in rCBV and PSR values between HGG and PCNSL patients, suggesting their potential for differentiation of these two types of tumors. Incorporating perfusion in routine MRI of contrast-enhancing lesions could significantly impact patient management.
WORLD NEUROSURGERY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sameer Taywade, Tanisha Gupta, Rajesh Kumar, Rahul Choudhary, Deepak Kumar
Summary: Nuclear imaging plays a crucial role in evaluating cardiac diseases of infective, inflammatory, innervation, and infiltrative origins. We report a case of persistent pyrexia after percutaneous transluminal coronary angioplasty in a patient with a history of inferior wall myocardial infarction. Molecular imaging techniques, such as F-18-FDG PET/CT and Tc-99m-MIBI myocardial perfusion study, helped in narrowing the differentials and eventually diagnosing the patient with Dressler syndrome.
CLINICAL NUCLEAR MEDICINE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Guohua Shen, Rang Wang, Lili Pan, Anren Kuang
Summary: Glomus tumors are vascular neoplasms arising from glomus bodies, typically found in tissues concentrated with these bodies. We reported the MRI and FDG PET/CT findings of a glomus tumor presenting as an axillary mass in a 25-year-old woman.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Oncology
Fei Wang, Rui Guo, Yan Zhang, Boqi Yu, Xiangxi Meng, Hanjing Kong, Yang Yang, Zhi Yang, Nan Li
Summary: This study investigated the value of F-18-FDG PET/MRI in the preoperative assessment of ESCC and compared it with other imaging methods. The results showed that F-18-FDG PET/MRI had higher accuracy and area under the curve in diagnosing primary tumors and regional lymph node metastases. Therefore, F-18-FDG PET/MRI may be a potential supplement or alternative imaging method for preoperative staging of ESCC.
FRONTIERS IN ONCOLOGY
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sophia Huntley Antippa, Leanne Du, Nathan Price, Charlie Chia-Tsong Hsu
Summary: Recognition of the imaging pattern of hyoid ORN is crucial for avoiding misdiagnosis and enabling prompt treatment. Hyoid ORN is a rare complication following radiation treatment for head and neck malignancy, with limited cases described in the literature.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shan-Shan Yang, Yi-Shan Wu, Wei-Chao Chen, Jun Zhang, Su-Ming Xiao, Bao-Yu Zhang, Zhi-Qiao Liu, En-Ni Chen, Xu Zhang, Pu-Yun Ouyang, Fang-Yun Xie
Summary: The study found that PET/CT outperformed MRI in diagnosing lymph nodes and staging nasopharyngeal carcinoma, leading to better survival rates and informed treatment decisions. Patients staged with PET/CT and MRI had higher survival rates, and a radiologic score model effectively stratified patients based on risk factors.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Benjamin J. Dewey, Benjamin M. Howe, Robert J. Spinner, Geoffrey B. Johnson, Mark A. Nathan, Doris E. Wenger, Stephen M. Broski
Summary: This study found that schwannomas may exhibit features associated with malignant peripheral nerve sheath tumors on MRI and FDG PET/CT imaging, including irregular margins, internal non-enhancement, perilesional edema, and heterogeneous FDG uptake. A significant proportion of lesions showed FDG activity above previously thought useful cutoff levels in differentiating malignant from benign peripheral nerve sheath tumors.
CLINICAL NUCLEAR MEDICINE
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Liu Xiao, Junjun Cheng, Lin Li
Summary: Soft tissue aneurysmal bone cyst is rare, and FDG PET/CT findings can be helpful in diagnosis, but pathology remains crucial for definitive diagnosis.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Birgit Pernthaler, Luka Brcic, Reingard Maria Aigner, Michael Fuchsjaeger, Emina Talakic
Summary: This article presents a rare case of primary malignant mesothelioma in the liver, with the patient being a 48-year-old woman who experienced increasing upper abdominal discomfort and inappetence, accompanied by a weight loss of approximately 10 kg. CT and MRI revealed a highly suspicious mass lesion in the liver. F-18-FDG PET/CT performed for staging showed a pathological F-18-FDG uptake of the known liver tumor. Histology and immunohistochemistry indicated mesothelioma of the liver.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yoshiharu Ohno, Takeshi Yoshikawa, Daisuke Takenaka, Hisanobu Koyama, Kota Aoyagi, Masao Yui, Yuka Oshima, Nayu Hamabuchi, Yumi Tanaka, Chika Shigemura, Seiichiro Oota, Masahiko Nomura, Kazuhiro Murayama, Yoshitaka Inui, Kaoru Kikukawa, Hiroshi Toyama
Summary: Whole-body MRI and FDG PET/MRI outperformed conventional staging tests and FOG PET/CT for staging of SCLC.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sayak Choudhury, Nilendu Purandare, Sneha Shah, Archi Agrawal, Venkatesh Rangarajan
Summary: Delayed-onset radiation-induced myelitis is a rare but serious complication of radiation exposure to the spinal cord. In this report, we describe the F-18-FDG PET/CT findings of radiation-induced myelitis in a patient with carcinoma of buccal mucosa treated with external beam radiotherapy.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Liu Xiao, Liu Yang, Yueqi Wang, Lin Li
Summary: Angiofibroma of soft tissue is a rare benign neoplasm. We reported a case in a 61-year-old woman, and MRI and PET/CT examinations were used for diagnosis.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Evyn Arnfield, David A. Pattison
Summary: A 69-year-old woman presented with symptomatic hypercalcemia and deranged liver function. Imaging studies showed intense activity in the liver parenchyma, which was later confirmed to be hepatic sarcoidosis through MRI and liver biopsy.
CLINICAL NUCLEAR MEDICINE
(2021)
Review
Oncology
Zhi Miao, Xiaomeng Zhao, Xuanwen Li
Summary: The purpose of this meta-analysis and systematic review was to compare the diagnostic performance of [18F]FDG PET/CT and [18F]FDG PET/MRI in colorectal liver metastasis. A total of 21 studies comprising 1036 patients were included. The results showed that [18F]FDG PET/CT and [18F]FDG PET/MRI have similar performance in detecting colorectal liver metastasis. However, larger prospective studies are needed due to limitations in the included studies.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Yang Yu, Le Zhang, Bilkis Sultana, Bo Wang, Hongzan Sun
Summary: This study investigated the diagnostic value of integrated positron emission tomography/magnetic resonance imaging (PET/MRI) for the staging of endometrial carcinoma. The results showed that PET/MRI had higher accuracy compared to PET/CT, especially for stage I tumors. PET/MRI quantitative parameters were associated with tumor stage and other clinicopathological characteristics.
Article
Radiology, Nuclear Medicine & Medical Imaging
Simone Krebs, Audrey Mauguen, Onur Yildirim, Vaios Hatzoglou, Jasmine H. Francis, Lauren R. Schaff, Ingo K. Mellinghoff, Heiko Schoder, Christian Grommes
Summary: The study found that in patients with CNS lymphomas undergoing ibrutinib-based therapies, higher lesional metabolic parameters on [F-18]FDG PET scans were inversely related to treatment outcomes. Specifically, high-intensity [F-18]FDG uptake and larger volumes of [F-18]FDG-avid disease were associated with poorer treatment responses.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Simone Krebs, Christian Grommes, Michael R. McDevitt, Sean D. Carlin, Joseph A. O'Donoghue, Maya S. Graham, Robert J. Young, Heiko Schoder, Philip H. Gutin, Neil H. Bander, Joseph R. Osborne
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nathaniel C. Swinburne, Vivek Yadav, Julie Kim, Ye R. Choi, David C. Gutman, Jonathan T. Yang, Nelson Moss, Jacqueline Stone, Jamie Tisnado, Vaios Hatzoglou, Sofia S. Haque, Sasan Karimi, John Lyo, Krishna Juluru, Karl Pichotta, Jianjiong Gao, Sohrab P. Shah, Andrei Holodny, Robert J. Young
Summary: This study investigates the use of clinically generated image annotations for training a brain MRI tumor detection model. The results show that semisupervised learning significantly improves tumor detection performance.
Correction
Radiology, Nuclear Medicine & Medical Imaging
Simone Krebs, Christian Grommes, Michael R. McDevitt, Sean D. Carlin, Joseph A. O'Donoghue, Maya S. Graham, Robert J. Young, Heiko Schoeder, Philip H. Gutin, Neil H. Bander, Joseph R. Osborne
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Andrei Holodny
Review
Radiology, Nuclear Medicine & Medical Imaging
Gary A. Ulaner
Summary: Estrogen receptor (ER) is highly expressed in 70%-80% of breast cancers and plays a central role in prognosis and treatment selection. The gold standard for determining ER status has been pathology, but it has limitations in providing spatial and temporal information and determining ER functionality. 16a-18F-fluoro-17b-Fluoroestradiol (FES) is a radiolabeled form of estrogen that allows non-invasive evaluation of functional ER. FES has shown correlation with ER immunohistochemistry, detection of ER heterogeneity, and high diagnostic accuracy for ER-positive tumors.
SEMINARS IN NUCLEAR MEDICINE
(2022)
Article
Oncology
Jonathan T. Yang, N. Ari Wijetunga, Elena Pentsova, Suzanne Wolden, Robert J. Young, Denise Correa, Zhigang Zhang, Junting Zheng, Alexa Steckler, Weronika Bucwinska, Ashley Bernstein, Allison Betof Warner, Helena Yu, Mark G. Kris, Andrew D. Seidman, Jessica A. Wilcox, Rachna Malani, Andrew Lin, Lisa M. DeAngelis, Nancy Y. Lee, Simon N. Powell, Adrienne Boire
Summary: Compared with photon IFRT, proton craniospinal irradiation (pCSI) improved CNS progression-free survival (PFS) and overall survival (OS) for patients with non-small-cell lung cancer and breast cancer with leptomeningeal metastasis (LM), with no increase in serious treatment-related adverse events (TAEs).
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Oncology
Brandon S. Imber, Robert J. Young, Kathryn Beal, Anne S. Reiner, Alexandra M. Giantini-Larsen, Jonathan T. Yang, David Aramburu-Nunez, Gil'ad N. Cohen, Cameron Brennan, Viviane Tabar, Nelson S. Moss
Summary: Salvage resection plus Cs131 brachytherapy may be a potential option for recurrent previously irradiated brain metastases, offering improved local control and toxicity profiles.
JOURNAL OF NEURO-ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gary A. Ulaner, Beth Thomsen, Jeffrey Bassett, Robert Torrey, Craig Cox, Kevin Lin, Trushar Patel, Tust Techasith, Audrey Mauguen, Steven P. Rowe, Liza Lindenberg, Esther Mena, Peter Choyke, Jeffrey Yoshida
Summary: The positive predictive value (PPV) of DCFPyL PET/CT was evaluated for suspected distant metastases and recurrence sites in newly diagnosed high-risk and biochemically recurrent (BCR) prostate cancer. The results showed a PPV of 74% in newly diagnosed prostate cancer and 89% in BCR prostate cancer. However, false-positive findings in ribs and pelvic bones should be considered.
Article
Oncology
Luca Pasquini, Mehrnaz Jenabi, Onur Yildirim, Patrick Silveira, Kyung K. Peck, Andrei I. Holodny
Summary: This study investigates the brain network modifications related to tumor grade and location using resting-state functional magnetic resonance imaging and graph theory. The results show that low-grade gliomas lead to increased efficiency of the surrounding functional network, while high-grade gliomas disrupt brain connectivity in remote areas. Tumor location also influences the pattern of network reorganization. Overall, low-grade gliomas may show more favorable network changes compared to high-grade gliomas.
Correction
Oncology
Brandon S. Imber, Robert J. Young, Kathryn Beal, Anne S. Reiner, Alexandra M. Giantini-Larsen, Simone Krebs, Jonathan T. Yang, David Aramburu-Nunez, Gil'ad N. Cohen, Cameron Brennan, Viviane Tabar, Nelson S. Moss
JOURNAL OF NEURO-ONCOLOGY
(2022)
Article
Oncology
Luca Pasquini, Kyung K. Peck, Alice Tao, Gino Del Ferraro, Denise D. Correa, Mehrnaz Jenabi, Erik Kobylarz, Zhigang Zhang, Cameron Brennan, Viviane Tabar, Hernan Makse, Andrei I. Holodny
Summary: This longitudinal study demonstrates the development of language plasticity in right-handed patients undergoing surgery for left-hemispheric low-grade glioma, characterized by the gradually increased involvement of the right hemisphere in language function. Two patterns of language reorganization were identified: type 1 changes may in part be treatment-related; type 2 may be tumor-induced, since atypical language organization was already present at baseline. Increased inter-hemispheric connectivity may represent the initial step in the development of plastic phenomena.
Article
Oncology
Felipe Camelo, Kyung K. Peck, Atin Saha, Julio Arevalo-Perez, John K. Lyo, Jamie Tisnado, Eric Lis, Sasan Karimi, Andrei I. Holodny
Summary: Radiologists use dynamic contrast-enhanced MRI to study cancer in the vertebral bones. However, the current method does not account for the delayed contrast uptake in spinal cancers, leading to misdiagnosis. Researchers shifted the contrast curve and recalculated the contrast enhancement values, resulting in more accurate detection of cancer in the vertebral bones.
Article
Hematology
Ashley Aaroe, Razelle Kurzrock, Gaurav Goyal, Aaron M. Goodman, Harsh Patel, Gordon Ruan, Gary Ulaner, Jason Young, Ziyi Li, Derek Dustin, Ronald S. Go, Eli L. Diamond, Filip Janku
Summary: ECD and RDD are rare non-LCHs with limited therapeutic options. The activation of the MAPK pathway through BRAFV600E mutation or other genomic alterations is a characteristic of histiocytosis and shows a positive response to BRAF inhibitors and the MEK inhibitor cobimetinib. This study retrospectively analyzed the outcomes of 26 adult patients treated with orally administered trametinib and found that the drug was effective in managing the diseases at low doses. The response rate was 71% in evaluable patients, including those without the detectable BRAFV600E mutation.
Article
Clinical Neurology
Mark Behar, Kyung K. Peck, Onur Yildirim, Jamie Tisnado, Atin Saha, Julio Arevalo-Perez, Eric Lis, Yoshiya Yamada, Andrei I. Holodny, Sasan Karimi
Summary: This study investigated the correlation between changes in dynamic contrast-enhanced MR imaging perfusion parameters and clinical outcomes following radiation therapy for spinal metastases. The study found that perfusion parameters outperformed traditional size measurements in discriminating treatment success and failure.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Apurva A. Bonde, Mayur Virarkar, Mohd Zahid, Sriram Jaganathan, Manuel J. Menendez, Luis Calimano, Bryan R. Foster, Danielle Fritze, Courtney L. Thomas, Pankaj Gupta
Summary: This article describes the common and uncommon appearances of gallbladder adenomyomatosis on multimodality imaging, helping differentiate it from non-benign gallbladder abnormalities, and providing important clinical and surgical management information.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Dheeman Futela, Suryansh Bajaj, Mihir Khunte, Xiao Wu, Seyedmehdi Payabvash, Dheeraj Gandhi, Ajay Malhotra
Article
Radiology, Nuclear Medicine & Medical Imaging
Renhui Cai, Juan Xu, Chaoqun Yan, Jie Wang, L. I. Wang, Leizhi Ku, Di Zhou, L. I. Zhu, Chunli He, Xinxiang Zhao, Xiaojing Ma
Summary: This paper analyzes the correlation between imaging features and ECG features in patients with coronary artery fistula (CAF). The study finds significant differences in ECG characteristics between coronary-cameral fistula (CCF) and coronary-pulmonary artery fistula (CPAF). Surgical treatment can improve ECG findings in some patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jordan Bozer, Kevin Peng, Melissa Magyer, Marilyn Niedermeier, Mina S. Makary
Summary: This study aimed to examine the impact of an educational website on patient understanding of Interventional Radiology (IR). The results showed that the use of an educational website can effectively improve patients' understanding of IR and familiarity with common interventional procedures.
Article
Radiology, Nuclear Medicine & Medical Imaging
Siavash Zamirpour, Marko T. Boskovski, James P. Pirruccello, William A. Pace, Alan E. Hubbard, Joseph R. Leach, Liang Ge, Elaine E. Tseng
Summary: This study evaluated sex-specific temporal changes in aortic size and sex differences in aortic reporting. The results showed that women had significantly higher aortic growth rates compared to men, and aortic dimensions were much less frequently reported in women than men.
Article
Radiology, Nuclear Medicine & Medical Imaging
Monica Miranda-Schaeubinger, Hermon Miliard Derbew, Alexandra Ramirez, Maretta Smith, Mohammad Jalloul, Savvas Andronikou, Hansel J. Otero
Summary: The prevalence of abnormal chest radiographs in patients with positive purified protein derivative (PPD) test was very low in a tertiary pediatric center in the United States. No cases of severe disease were identified, and patients with abnormal findings did not require a change in treatment according to current WHO guidelines.
Article
Radiology, Nuclear Medicine & Medical Imaging
A. Sailer, K. Fitzgerald, J. F. B. Chick, D. S. Shin, E. J. Monroe
Summary: This manuscript describes an approach to successful common femoral arterial access and arteriography in infants, highlighting common pearls and pitfalls.
Article
Radiology, Nuclear Medicine & Medical Imaging
Apurva Bonde, Alice W. Fung, Skye C. Mayo, Peter Li, Brett S. Walker, Sriram Jaganathan, Nadine Mallak, Elena K. Korngold
Summary: Hepatic arterial infusion pumps allow selective administration of chemotherapy to the liver, maximizing its effects while minimizing systemic toxicity. Radiologists play a crucial role in pre-operative planning, treatment response assessment, and evaluation of potential complications. This article aims to familiarize radiologists with various aspects of HAI pumps.
Article
Radiology, Nuclear Medicine & Medical Imaging
Huseyin Bilgin, Ercan Ayaz
Summary: By examining radiographs of children with mucopolysaccharidosis, early diagnosis can be achieved before clinical symptoms become prominent. Therefore, X-ray screening of children in endemic regions of mucopolysaccharidosis is feasible.