Article
Gastroenterology & Hepatology
Mehul Lamba, Jing Hieng Ngu, Catherine A. M. Stedman
Summary: In a population-based prospective study conducted in Canterbury, New Zealand, it was found that the incidence of autoimmune hepatitis (AIH) was significantly higher in the period of 2014-2016 compared to 2008-2010, while the incidences of primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) remained unchanged over the same period. Further research is needed to understand the reasons for these changes in incidence rates of autoimmune liver diseases.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Rheumatology
Ali Duarte-Garcia, Mehmet Hocaoglu, Maria Valenzuela-Almada, Shirley-Ann Osei-Onomah, Jesse Y. Dabit, Alain Sanchez-Rodriguez, Stephanie Q. Duong, Rachel E. Giblon, Hannah E. Langenfeld, Graciela S. Alarcon, Charles G. Helmick, Cynthia S. Crowson
Summary: The incidence and prevalence of systemic lupus erythematosus (SLE) are increasing in the US population, potentially due to the rising ethnic diversity. However, the severity of SLE and the survival gap between SLE and the general population have remained unchanged over time.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Rheumatology
Zachary S. Wallace, Gandarvaka Miles, Ekaterina Smolkina, Natalia Petruski-Ivleva, Duane Madziva, Claire Cook, Xiaoqing Fu, Yuqing Zhang, John H. Stone, Hyon K. Choi
Summary: This study describes the epidemiology of IgG4-related disease (IgG4-RD) in the USA, finding that the incidence and prevalence of IgG4-RD are increasing, and patients with IgG4-RD have a higher risk of death.
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Article
Gastroenterology & Hepatology
Jiahui Yang, Fangli Wu, Hongjin An, Huatian Gan
Summary: This study aimed to investigate the incidence and risk factors for second primary malignancies among survivors diagnosed with colorectal cancer. The results showed that the most common sites of second primary malignancies were colorectal cancer, lung cancer, and bronchus cancer. Older age, male gender, married status, and localized stage of colorectal cancer were associated with a higher risk of second primary malignancies. Additionally, radiation therapy was found to increase the risk of second primary malignancies.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)
Article
Rheumatology
Paola Ghanem, Joseph C. Murray, Kristen A. Marrone, Susan C. Scott, Josephine L. Feliciano, Vincent K. Lam, Christine L. Hann, David S. Ettinger, Benjamin P. Levy, Patrick M. Forde, Ami A. Shah, Christopher Mecoli, Julie Brahmer, Laura C. Cappelli
Summary: Lung cancer patients with concomitant autoimmune rheumatic diseases (ARD) have different tumor characteristics and clinical outcomes compared to those without ARD. Patients with ARD are more likely to be diagnosed with early-stage lung cancer and have a longer overall survival (OS).
Article
Gastroenterology & Hepatology
Junjie Huang, Sze Chai Chan, Yat Ching Fung, Fung Yu Mak, Veeleah Lok, Lin Zhang, Xu Lin, Don Eliseo Lucero-prisno, Wanghong Xu, Zhi-Jie Zheng, Edmar Elcarte, Mellissa Withers, Martin C. S. Wong
Summary: This study comprehensively analyzed the incidence, risk factors, and trends of small intestinal cancer by sex, age, and country. It found a significant geographic disparity in the burden of small intestinal cancer, with higher incidence in countries with higher human development index, gross domestic product, and prevalence of unhealthy lifestyle habits, metabolic disorders, and inflammatory bowel disease. The study also revealed an overall increasing trend in small intestinal cancer incidence.
Article
Clinical Neurology
Marie Kim Wium-Andersen, Ida Kim Wium-Andersen, Terese Sara Hoj Jorgensen, Martin Balslev Jorgensen, Merete Osler
Summary: Patients with affective disorder have higher absolute and relative risks of most somatic diseases, except for cancers. The strongest associations were found for dementia, hip fracture, COPD, and stroke on both the relative and absolute scale. Further research on shared mechanisms could lead to targeted interventions to reduce the risk.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Oncology
Abdallah Al-Ani, Justin Z. Amarin, Leen Al-Huneidy, Maysa Al-Hussaini
Summary: This study investigated the consistent trends of female survival advantage in cancer among Jordanian patients across different age groups and nonsex specific cancer types. The results showed that females exhibited better overall survival in the adolescent and young adult (AYA) and older adults' groups. Further studies are needed to examine the underlying factors causing this discrepancy and develop sex-specific interventions.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Oncology
Julie A. Bytnar, Katherine A. Mcglynn, Matthew D. Nealeigh, Craig D. Shriver, Kangmin Zhu
Summary: The incidence of breast and prostate cancers is higher in the US military compared to the general population, while the incidence of colorectal, lung, and testicular cancers is lower. This may be due to higher cancer screening utilization or cumulative military exposures. Better health status among servicemembers may contribute to the lower incidence of other cancers.
Article
Dermatology
Jenny G. Chung, Rajan Ramji, Christin Coomarasamy, Paul Jarrett, Marius Rademaker, Denesh C. Patel
Summary: The study found that the incidence and mortality rates of bullous pemphigoid in New Zealand are comparable to that in the UK and Northern Europe. Patients are mostly of European and Pacific Islander descent, with a high prevalence of cognitive impairment and stroke.
AUSTRALASIAN JOURNAL OF DERMATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Eileen Morgan, Melina Arnold, A. Gini, V Lorenzoni, C. J. Cabasag, Mathieu Laversanne, Jerome Vignat, Jacques Ferlay, Neil Murphy, Freddie Bray
Summary: Colorectal cancer is the third most common cancer worldwide, with the highest incidence rates in Australia/New Zealand and Europe, and the lowest rates in Africa and Southern Asia. The burden of colorectal cancer is projected to increase by 2040, with the majority of cases predicted to occur in high HDI countries.
Article
Medicine, General & Internal
Farhana Badar, Shahid Mahmood
Summary: The study aimed to investigate the cancer incidence rates in Lahore, Pakistan from 2010 to 2019, and found that there were more cases of cancer in females than males, with breast cancer, prostate cancer, lymphoid leukaemia, and bone tumour being among the types with higher incidence rates.
Article
Oncology
Fangcheng Yuan, Ruth M. Pfeiffer, Sachelly Julian-Serrano, Simran Arjani, Michael J. Barrett, Jill Koshiol, Rachael Z. Stolzenberg-Solomon
Summary: There is an association between autoimmune conditions and pancreatic cancer risk, with certain autoimmune conditions being associated with an increased risk of pancreatic cancer.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Multidisciplinary Sciences
Bolun Zhou, Fenglong Bie, Ruochuan Zang, Moyan Zhang, Peng Song, Lei Liu, Yue Peng, Guangyu Bai, Qilin Huai, Yuan Li, Liang Zhao, Shugeng Gao
Summary: This study provides a comprehensive analysis of the global geographic patterns and temporal trends in the mortality and incidence of oesophageal cancer. The results show that the mortality and incidence trends have significantly decreased in most countries of South America and Asia, but varied in European countries. The study highlights the importance of implementing preventative efforts for populations with rising mortality and incidence trends.
JOURNAL OF ADVANCED RESEARCH
(2023)
Article
Medicine, General & Internal
Sven H. Loosen, Markus S. Joerdens, Mark Luedde, Dominik P. Modest, Simon Labuhn, Tom Luedde, Karel Kostev, Christoph Roderburg
Summary: The symptoms suggest that IBS may be associated with cancer of the digestive organs as well as non-digestive cancer entities. However, this association does not prove causality, and further research is needed to determine if lifestyle factors not documented in the database may be influencing it.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Wenjie Ma, Marjorie M. Walker, Marcus Thuresson, Bjorn Roelstraete, Filip Skoldberg, Ola Olen, Lisa L. Strate, Andrew T. Chan, Jonas F. Ludvigsson
Summary: This study found that patients with diverticular disease who have colorectal histopathology have a 33% increased risk of overall incident cancer, with specific increases in colon, liver, pancreatic, and lung cancers.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Review
Pediatrics
Jonas F. Ludvigsson, Jan Adolfsson, Malin Hoistad, Per-Anders Rydelius, Berit Kristroem, Mikael Landen
Summary: This systematic review aims to assess the effects of hormone treatment on psychosocial and mental health, cognition, body composition, and metabolic markers in children with gender dysphoria. The review identified 24 relevant English-language studies, but the evidence was insufficient to evaluate the effects of hormone therapy in these areas. Further research is needed to better understand the impacts of hormone treatment in children with gender dysphoria.
Editorial Material
Gastroenterology & Hepatology
Xiaoying Kang, Shengxin Liu, Jonas F. Ludvigsson
Summary: This article is related to the papers by Kang et al. To access these articles, please visit...
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Letter
Gastroenterology & Hepatology
Hannes Hagstroem, Jonas F. F. Ludvigsson
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Xiaoying Kang, Shengxin Liu, Bjorn Roelstraete, Hamed Khalili, Jonas F. Ludvigsson
Summary: This study examined the association between type 1 diabetes (T1D) and microscopic colitis (MC). The results showed that the prevalence of T1D was almost 80% higher in MC patients compared to the general population. This association may be related to the consumption of medications associated with MC onset.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Haley M. Zylberberg, Benjamin Lebwohl, Bjorn Roelstraete, Jonas Soederling, Olof Stephansson, Peter H. R. Green, Jonas F. Ludvigsson
Summary: This study aimed to investigate the risk of cardiac birth defects in infants born to mothers with celiac disease (CeD). The results showed no statistically significant association between maternal CeD and the risk of any or cardiac birth defects in the offspring, compared to the general population and non-affected siblings.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Letter
Hematology
Qingling Su, Weimin Ye
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Fahim Ebrahimi, Tracey G. Simon, Hannes Hagstrom, Jonas Soderling, Axel Wester, Bjorn Roelstraete, Jonas F. Ludvigsson
Summary: Patients with biopsy-proven NAFLD have a significantly higher risk of developing severe infections requiring hospitalization compared to the general population and their siblings. The risk of infection increases with the severity of NAFLD.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Letter
Gastroenterology & Hepatology
Jonas F. Ludvigsson
Correction
Public, Environmental & Occupational Health
J. F. Ludvigsson, P. Appelros, J. Askling
CLINICAL EPIDEMIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Asa Everhov, Jonas Soederling, Gustaf Befrits, Hamed Khalili, Gabriella Broems, Martin Neovius, Johan Askling, Jonas F. Halfvarson, Jonas Ludvigsson, Ola Olen, SWIBREG Study Group
Summary: This study assessed the costs of prevalent Crohn's disease (CD) or ulcerative colitis (UC) patients in Sweden from 2007 to 2020, including productivity losses. The study found that in recent years, the costs of patients mainly came from healthcare costs, rather than productivity losses. Particularly, the use of biologics contributed to the increase in healthcare costs.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
David Bergman, Bjorn Roelstraete, Jiangwei Sun, Fahim Ebrahimi, Johan Askling, Jonas F. Ludvigsson
Summary: A study found that there is an association between microscopic colitis (MC) and rheumatoid arthritis (RA), with MC patients being nearly twice as likely to develop RA compared to the general population. This study is important as it highlights the need for expedited evaluation for RA in MC patients presenting with joint symptoms and/or arthralgia, thus preventing delay in RA diagnosis.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Gastroenterology & Hepatology
Kyle Staller, Ola Olen, Jonas Soderling, Bjorn Roelstraete, Hans Tornblom, Braden Kuo, Long H. Nguyen, Jonas F. Ludvigsson
Summary: The study found that previous use of antibiotics was associated with an increased risk of developing irritable bowel syndrome (IBS), particularly among those with multiple antibiotic dispensations.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Public, Environmental & Occupational Health
Patrik Nasr, Erik von Seth, Raphaela Mayerhofer, Nelson Ndegwa, Jonas F. F. Ludvigsson, Hannes Hagstrom
Summary: The incidence rates of non-alcoholic fatty liver disease, alcohol-related cirrhosis, unspecified liver cirrhosis, and liver malignancies have increased in Sweden over the last 15 years. There has also been an increase in mortality rates for several liver diseases. Significant disparities across sex and geographical regions need to be considered when allocating healthcare resources.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Weiyao Yin, Jonas F. Ludvigsson, Ulrika Aden, Kari Risnes, Martina Persson, Abraham Reichenberg, Michael E. Silverman, Eero Kajantie, Sven Sandin
Summary: This study investigated the association between psychiatric diagnoses in fathers, mothers, and both parents and gestational age. The results showed that both paternal and maternal psychiatric diagnoses were associated with earlier gestational age, and the risk increased when both parents were diagnosed. The risk also increased when fathers and mothers were diagnosed with different psychiatric disorders. These findings suggest that the presence of psychiatric diagnoses in parents impacts gestational age at birth.