Subcutaneous pulsatile glucocorticoid replacement therapy

Cardio-metabolic consequences of glucocorticoid replacement: relevance of ultradian signalling

(2014) David E. Henley et al.   CLINICAL ENDOCRINOLOGY

The importance of dynamic signalling for endocrine regulation and drug development: relevance for glucocorticoid hormones

(2014) Stafford Lightman et al.   Lancet Diabetes & Endocrinology

ACTH-Dependent Ultradian Rhythm of Corticosterone Secretion

(2011) Francesca Spiga et al.   ENDOCRINOLOGY

Association of Diurnal Patterns in Salivary Cortisol with All-Cause and Cardiovascular Mortality: Findings from the Whitehall II Study

(2011) Meena Kumari et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Improved Cortisol Exposure-Time Profile and Outcome in Patients with Adrenal Insufficiency: A Prospective Randomized Trial of a Novel Hydrocortisone Dual-Release Formulation

(2011) G. Johannsson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Stress Responsiveness Varies over the Ultradian Glucocorticoid Cycle in a Brain-Region-Specific Manner

(2010) Ratna A. Sarabdjitsingh et al.   ENDOCRINOLOGY

Rapid Glucocorticoid Receptor-Mediated Inhibition of Hypothalamic-Pituitary-Adrenal Ultradian Activity in Healthy Males

(2010) G. M. Russell et al.   JOURNAL OF NEUROSCIENCE

The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration

(2010) Stafford L. Lightman et al.   NATURE REVIEWS NEUROSCIENCE

A pharmacokinetic and pharmacodynamic study of delayed- and extended-release hydrocortisone (ChronocortTM)vs.conventional hydrocortisone (CortefTM) in the treatment of congenital adrenal hyperplasia

(2009) Somya Verma et al.   CLINICAL ENDOCRINOLOGY

Inadequacies of glucocorticoid replacement and improvements by physiological circadian therapy

(2009) Miguel Debono et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Hypothalamic-Pituitary-Adrenal Axis Activation in Obstructive Sleep Apnea: The Effect of Continuous Positive Airway Pressure Therapy

(2009) David E. Henley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

(2009) Diana A. Stavreva et al.   NATURE CELL BIOLOGY

Impaired subjective health status in chronic adrenal insufficiency: impact of different glucocorticoid replacement regimens

(2008) Benjamin Bleicken et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The significance of glucocorticoid pulsatility

(2008) Stafford L. Lightman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY