Article
Endocrinology & Metabolism
Carine Marmentini, Gabriela M. Soares, Gabriela A. Bronczek, Silvano Piovan, Cecilia E. Mareze-Costa, Everardo M. Carneiro, Antonio C. Boschero, Mirian A. Kurauti
Summary: Although insulin sensitivity was unaffected in old mice, glucose tolerance appeared to increase during the intraperitoneal glucose tolerance test, accompanied by higher plasma insulin levels. The reduced insulin clearance in old mice may be related to the decreased hepatic CEACAM1 and IDE function.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Ulla Kampmann, Esben S. Lauritzen, Niels Grarup, Niels Jessen, Torben Hansen, Niels Moller, Julie Stoy
Summary: The study found that acute administration of high doses of melatonin may reduce insulin sensitivity, especially in certain genotype carriers.
JOURNAL OF PINEAL RESEARCH
(2021)
Article
Oncology
Jane C. Figueiredo, Gillian Gresham, Elizabeth L. Barry, Leila A. Mott, Michael N. Passarelli, Patrick T. Bradshaw, Carlton W. Anderson, John A. Baron
Summary: This study investigated the relationship between sex hormone levels and risk of colorectal precursors in 925 men. The findings fill the gap in the research on sex hormones in men.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Multidisciplinary Sciences
J. Philip Karl, Claire C. Whitney, Marques A. Wilson, Heather S. Fagnant, Patrick N. Radcliffe, Nabarun Chakraborty, Ross Campbell, Allison Hoke, Aarti Gautam, Rasha Hammamieh, Tracey J. Smith
Summary: This study aimed to determine the effects of severe, short-term sleep restriction on gut microbiota composition and intestinal permeability in healthy adults. The findings indicated that severe, short-term sleep restriction reduced the richness of the gut microbiota but had minimal impact on community composition and did not affect intestinal permeability in healthy young men.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Lello Zolla, Marcello Ceci
Summary: In male hypogonadism patients, testosterone replacement therapy (TRT) improves glucose utilization, branched amino acid and carnosine metabolism, but does not activate fatty acid oxidation. Lipid metabolism shows delayed improvement, and both malate and glycerol shuttle are reduced, leading to lower NADH and ATP levels, with increased lactate production.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Kai Ma, Qiang Dong
Summary: The study aimed to examine the association between sleep quality and benign prostate hyperplasia (BPH) among middle-aged and older men in India. The results showed that worse sleep quality was significantly associated with a higher incidence of BPH among middle-aged and older Indian men. Further prospective studies are needed to clarify this association and explore potential mechanisms.
Article
Endocrinology & Metabolism
Jose Carlos Fernandez-Garcia, Rocio Barrios-Rodriguez, Maite Asenjo-Plaza, Bruno Ramos-Molina, Maria Molina-Vega, Antonio Guzman-Guzman, Luis Moreno-Leon, Elena M. Yubero-Serrano, Francisca Rius-Diaz, Sergio Valdes, Miguel Angel Martinez-Gonzalez, Jose Juan Jimenez-Moleon, Francisco J. Tinahones
Summary: Among men with obesity and low testosterone concentrations, the combination of metformin plus testosterone, metformin only, and testosterone only, compared to placebo, reduced insulin resistance with no evidence of additive benefit.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2022)
Article
Behavioral Sciences
A. M. Lotz, R. S. M. Buisman, K. Alyousefi-van Dijk, A. M. Witte, M. J. Bakermans-Kranenburg, M. W. F. T. Verhees
Summary: This study explores the hormonal correlates of paternal sensitivity and finds no significant associations between sensitivity and basal hormone levels or reactivity. However, it reveals an interaction between cortisol and testosterone in their effects on paternal sensitive parenting.
HORMONES AND BEHAVIOR
(2022)
Article
Nutrition & Dietetics
Andrew Wilhelmsen, Amanda Davies, Joanne Mallinson, Pardeep Pabla, Robert Jones, Elliott A. Palmer, Warwick B. Dunn, Gordon W. Moran, Francis B. Stephens, Kostas Tsintzas
Summary: Omega-3 polyunsaturated fatty acids (n-3 PUFA) may protect against the insulin resistance caused by saturated fatty acids (SFA). This study found that an oral fat pre-load, especially fish oil, affected the early postprandial uptake of branched chain amino acids (BCAA) in response to protein and glucose, but did not significantly impact insulin sensitivity.
CLINICAL NUTRITION
(2022)
Article
Endocrinology & Metabolism
Flavia Tosi, Michela Villani, Sabrina Garofalo, Giulia Faccin, Enzo Bonora, Tom Fiers, Jean-Marc Kaufman, Paolo Moghetti
Summary: Serum levels of 11-oxygenated androgens are higher in women with PCOS than in controls. However, these hormones show a poor performance in recognizing women with hyperandrogenism, as currently defined. The relationships of these androgens with insulin sensitivity strongly differ from that of FT, suggesting a different role of classic and 11-oxygenated androgens in the pathophysiology of PCOS.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biology
Vanessa Sanchez-Martinez, Cristina Buigues, Rut Navarro-Martinez, Laura Garcia-Villodre, Noura Jeghalef, Maria Serrano-Carrascosa, Jose Rubio-Briones, Omar Cauli
Summary: This study found significant changes in cognitive assessment, depressive symptoms, and sleep quality in men with prostate cancer undergoing ADT after one year of treatment. However, there was no statistically significant relationship between cognitive performance and impaired sleep or depression results.
Article
Endocrinology & Metabolism
Lieve T. van Egmond, Elisa M. S. Meth, Joachim Engstrom, Maria Ilemosoglou, Jasmin Annica Keller, Heike Vogel, Christian Benedict
Summary: This study investigates the effects of acute total sleep deprivation on blood concentrations of leptin, ghrelin, and adiponectin. The results show that sleep deprivation reduces levels of leptin while increasing levels of ghrelin and adiponectin. These changes are more pronounced in women and among individuals with obesity.
Review
Endocrinology & Metabolism
Richard L. Hauger, Ursula G. Saelzler, Meghana S. Pagadala, Matthew S. Panizzon
Summary: Considerable research has shown that low levels of testosterone are associated with increased risk for depression. However, the effectiveness of testosterone replacement therapy in treating depression in men with low testosterone levels remains uncertain and requires further investigation. Important factors to consider include the heterogeneity of major depressive disorder and the potential role of polygenic mechanisms in influencing the interaction between testosterone and depression.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2022)
Article
Nutrition & Dietetics
Juliane Richter, Narona Thordsen, Kai Duysen, Kerstin M. Oltmanns
Summary: A low-calorie saccharide preload significantly reduces subsequent food intake and overall calorie consumption, indicating it could be a promising support for reducing caloric intake. This study suggests a potential strategy for weight loss by triggering feelings of satiety through oral ingestion of carbohydrates.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Endocrinology & Metabolism
Yun Hu, Ying Wang, Ting-ting Cai, Lu Liu, Dong-mei Li, Jian-hua Ma, Bo Ding
Summary: Short-term intensive insulin therapy can increase serum testosterone levels in men with newly diagnosed type 2 diabetes, possibly due to enhanced conversion of DHEA to testosterone.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Andrology
R. Ayoub, S. T. Page, R. S. Swerdloff, P. Y. Liu, J. K. Amory, A. Leung, L. Hull, D. Blithe, A. Christy, J. H. Chao, W. J. Bremner, C. Wang
Article
Pharmacology & Pharmacy
Jing Jing, Cara Nelson, Jisun Paik, Yoshiyuki Shirasaka, John K. Amory, Nina Isoherranen
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
(2017)
Article
Obstetrics & Gynecology
Jisun Paik, Piper M. Treuting, Michael Haenisch, John K. Amory
Article
Medicine, Research & Experimental
Abdul Basit, John K. Amory, Bhagwat Prasad
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2018)
Article
Pharmacology & Pharmacy
Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder, Bhagwat Prasad
DRUG METABOLISM AND DISPOSITION
(2018)
Article
Endocrinology & Metabolism
Michael Haenisch, Piper M. Treuting, Thea Brabb, Alex S. Goldstein, Kathryn Berkseth, John K. Amory, Jisun Paik
OBESITY RESEARCH & CLINICAL PRACTICE
(2018)
Article
Endocrinology & Metabolism
Arthi Thirumalai, Jonas Ceponis, John K. Amory, Ronald Swerdloff, Vijaya Surampudi, Peter Y. Liu, William J. Bremner, Eric Harvey, Diana L. Blithe, Min S. Lee, Laura Hull, Christina Wang, Stephanie T. Page
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2019)
Article
Endocrinology & Metabolism
Sherry Wu, Fiona Yuen, Ronald S. Swerdloff, Youngju Pak, Arthi Thirumalai, Peter Y. Liu, John K. Amory, Feng Bai, Laura Hull, Diana L. Blithe, Bradley D. Anawalt, Toufan Parman, Kyuri Kim, Min S. Lee, William J. Bremner, Stephanie T. Page, Christina Wang
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2019)
Editorial Material
Endocrinology & Metabolism
Stephanie T. Page, John K. Amory
NATURE REVIEWS ENDOCRINOLOGY
(2018)
Article
Endocrinology & Metabolism
Kathryn E. Berkseth, Katya B. Rubinow, Susan J. Melhorn, Mary F. Webb, Mary Rosalynn B. De Leon, Brett T. Marck, Alvin M. Matsumoto, John K. Amory, Stephanie T. Page, Ellen A. Schur
Article
Medicine, Research & Experimental
Faith Stevison, Mika Kosaka, Jane R. Kenny, Susan Wong, Cathryn Hogarth, John K. Amory, Nina Isoherranen
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2019)
Article
Andrology
B. D. Anawalt, M. Y. Roth, J. Ceponis, V. Surampudi, J. K. Amory, R. S. Swerdloff, P. Y. Liu, C. Dart, W. J. Bremner, R. Sitruk-Ware, N. Kumar, D. L. Blithe, S. T. Page, C. Wang
Article
Biochemistry & Molecular Biology
Yan Chen, Jin-Yi Zhu, Kwon Ho Hong, David C. Mikles, Gunda I. Georg, Alex S. Goldstein, John K. Amory, Ernst Schonbrunn
ACS CHEMICAL BIOLOGY
(2018)
Article
Endocrinology & Metabolism
Katya B. Rubinow, Jing H. Chao, Derek Hagman, Mario Kratz, Brian Van Yserloo, Nilesh W. Gaikwad, John K. Amory, Stephanie T. Page
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2017)
Article
Endocrinology & Metabolism
Arthi Thirumalai, Katya B. Rubinow, Lori A. Cooper, John K. Amory, Brett T. Marck, Alvin M. Matsumoto, Stephanie T. Page
CLINICAL ENDOCRINOLOGY
(2017)
