Effect of Inhibition of Cytochrome P450 Enzymes 2D6 and 3A4 on the Pharmacokinetics of Intravenous Oxycodone

Exposure to oral oxycodone is increased by concomitant inhibition of CYP2D6 and 3A4 pathways, but not by inhibition of CYP2D6 alone

(2010) Juha Grönlund et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone

(2010) Teijo I. Saari et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Impact of theCYP2D6genotype on post-operative intravenous oxycodone analgesia

(2009) S. T. ZWISLER et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Effect of Telithromycin on the Pharmacokinetics and Pharmacodynamics of Oral Oxycodone

(2009) Juha Grönlund et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Intestinal First-Pass Metabolism of CYP3A4 Substrates

(2008) Motohiro Kato   Drug Metabolism and Pharmacokinetics

Voriconazole drastically increases exposure to oral oxycodone

(2008) Nora M. Hagelberg et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Determination of Oxycodone, Noroxycodone, Oxymorphone, and Noroxymorphone in Human Plasma by Liquid Chromatography-Electrospray-Tandem Mass Spectrometry

(2008) Mikko Neuvonen et al.   THERAPEUTIC DRUG MONITORING