Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of Ras Signaling by Blocking Ras-Effector Interactions with Cyclic Peptides
Authors
Keywords
-
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 26, Pages 7602-7606
Publisher
Wiley
Online
2015-05-07
DOI
10.1002/anie.201502763
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices
- (2015) Elizaveta S. Leshchiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery
- (2014) Ziqing Qian et al. BIOCHEMISTRY
- Dragging Ras Back in the Ring
- (2014) Andrew G. Stephen et al. CANCER CELL
- Small-molecule modulation of Ras signaling
- (2014) Jochen Spiegel et al. Nature Chemical Biology
- Direct Ras inhibitors identified from a structurally rigidified bicyclic peptide library
- (2014) Punit Upadhyaya et al. TETRAHEDRON
- Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor
- (2013) Sang Min Lim et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance
- (2013) Esther Castellano et al. CANCER CELL
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
- Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling
- (2013) Gunther Zimmermann et al. NATURE
- In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction
- (2013) F. Shima et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs
- (2012) Ziqing Qian et al. ACS Chemical Biology
- Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation
- (2012) Qi Sun et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ras inhibition via direct Ras binding—is there a path forward?
- (2012) Weiru Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A Comprehensive Survey of Ras Mutations in Cancer
- (2012) I. A. Prior et al. CANCER RESEARCH
- Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
- (2012) T. Maurer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Ras–effector interactions by cyclic peptides
- (2012) Xianghong Wu et al. MedChemComm
- Inhibition of Ras for cancer treatment: the search continues
- (2011) Antonio T Baines et al. Future Medicinal Chemistry
- An orthosteric inhibitor of the Ras-Sos interaction
- (2011) Anupam Patgiri et al. Nature Chemical Biology
- Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
- (2009) M. L. Sos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
- (2008) Jeffrey A Engelman et al. NATURE MEDICINE
- Ras oncogenes: split personalities
- (2008) Antoine E. Karnoub et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started