Article
Medical Laboratory Technology
Edmund H. Wilkes
Summary: According to international standards, clinical laboratories need to verify assay performance before routine practice. This paper presents an open-source software for Bayesian analysis of verification data, aiming to make Bayesian analyses more accessible. The software allows evaluation of imprecision, trueness, method comparison, and diagnostic performance within a Bayesian framework.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Psychology, Clinical
Peng Wang, Haotian Liu, Xiao Wang, Xiqing Yuan, Yu Sun, Li Xiao, Wenxuan Li, Chong Ma
Summary: The study revised Carter's IT Identity Scale in the context of Chinese cultural background and confirmed that the Chinese version is congruent with the English version in terms of structure, validity, and reliability. The results showed that the Chinese version of the scale presented satisfactory psychometric properties and shared many similarities with the original version, indicating suitability for use in the Chinese cultural context.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2022)
Article
Computer Science, Artificial Intelligence
Fei-Yue Wang, Jia Hu, Jintao Lai
Summary: This paragraph informs readers that it is only a summary of the articles presented in this issue of the publication.
IEEE TRANSACTIONS ON INTELLIGENT VEHICLES
(2023)
Article
Medicine, General & Internal
Casper G. M. J. Eurlings, Sema Bektas, Sandra Sanders-van Wijk, Andrew Tsirkin, Vasily Vasilchenko, Steven J. R. Meex, Michael Failer, Caroline Oehri, Peter Ruff, Michael J. Zellweger, Hans-Peter Brunner-La Rocca
Summary: This study presents a new model, called the MPA model, for predicting coronary artery disease (CAD) with the aim of improving risk stratification for non-invasive diagnosis. The results showed that the MPA model had better accuracy in predicting CAD compared to traditional risk scores in a low- to intermediate-risk population.
Review
Computer Science, Software Engineering
Hugo Araujo, Mohammad Reza Mousavi, Mahsa Varshosaz
Summary: This paper presents a systematic literature review on testing, validation, and verification of robotic and autonomous systems (RAS). The review focuses on peer-reviewed research papers that propose, improve, or evaluate testing techniques, processes, or tools for the system-level qualities of RAS. The findings show the types of models used, measures for system performance and testing adequacy, availability of tools, and evidence of applicability, with recommendations for researchers and practitioners.
ACM TRANSACTIONS ON SOFTWARE ENGINEERING AND METHODOLOGY
(2023)
Article
Computer Science, Information Systems
Kyoung-Sook Kim, Dinh-Lam Pham, Young-In Park, Kwanghoon Pio Kim
Summary: This paper verifies the functional correctness of a specific process mining algorithm and validates its requirement satisfaction. The algorithm aims to discover various structural process patterns from a dataset of process enactment event logs and build a structured business process model. Through experiments, it is shown that the q-Algorithm is theoretically safe, functionally operable, and practically applicable to process mining systems.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2022)
Article
Psychology, Multidisciplinary
David Robert Skvarc, Matthew Talbot, Travis Harries, Christopher J. Wilson, Nicki Joshua, Linda K. Byrne
Summary: This study found that the home ICT environment and its usage have limited impacts on students' academic performance, though being correlated with factors such as household income and parental education. Students' ICT affinity shows a small positive correlation with academic performance, while showing negative associations with social media usage and educational TV viewing.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Physics, Multidisciplinary
C. Greganti, T. F. Demarie, M. Ringbauer, J. A. Jones, V Saggio, I. Alonso Calafell, L. A. Rozema, A. Erhard, M. Meth, L. Postler, R. Stricker, P. Schindler, R. Blatt, T. Monz, P. Walther, J. F. Fitzsimons
Summary: The study introduces a cross-verification technique that utilizes the principles of quantum computation for checking the results of quantum computers. Through consistency checks of different quantum circuits, the technique enables verification of quantum computations between independent devices and within a single device.
Article
Psychology, Multidisciplinary
Lydia Paulin Schidelko, Britta Schuenemann, Hannes Rakoczy, Marina Proft
Summary: This article discusses the validity of a low-cost and easy-to-implement online testing approach by comparing children's performance on a well-established task in in-lab and online settings. The results suggest that the typical developmental pattern of performance in these tasks found in in-lab studies could be replicated with the novel online test procedure, offering a valid alternative to classical in-person test settings.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Medicine, General & Internal
Zahra Azizi, Chaoyi Zheng, Lucy Mosquera, Louise Pilote, Khaled El Emam
Summary: The study replicated a published stage III colon cancer trial secondary analysis using synthetic data generated by a machine learning method. The results showed high concordance between the analytical results and conclusions from synthetic and real data, indicating that synthetic data can be used as a reasonable proxy for real clinical trial datasets.
Article
Genetics & Heredity
Anthony Scott, Donna M. Martin
Summary: Genetic testing and result return in pediatric settings require patient follow-up, referrals, and coordination between providers. The Pediatric Genetic Tracking episodes system serves as a centralized summary for tracking patient genetic information and facilitates communication to support timely and accurate return of results.
GENETICS IN MEDICINE
(2021)
Article
Computer Science, Software Engineering
Damjan Ekert, Juergen Dobaj, Alen Salamun
Summary: Modern cars are equipped with multiple ECUs that require cybersecurity integration tests to fulfil homologation requirements. These tests impact the way car communication infrastructure is tested and which cybersecurity attack patterns are checked before a road release.
JOURNAL OF UNIVERSAL COMPUTER SCIENCE
(2021)
Article
Computer Science, Information Systems
Alba Fernandez-Izquierdo, Raul Garcia-Castro
Summary: Ontology verification is an essential activity in ontology development, ensuring that ontologies are built correctly in compliance with their specifications. This paper proposes a method using lexico-syntactic patterns and ontologies to define testing activities and provides an online tool for executing tests. User evaluation showed that tools utilizing testing languages had better results in reducing errors compared to those that do not.
INFORMATION SCIENCES
(2022)
Article
Physics, Multidisciplinary
Yong Yu, Peng-Fei Sun, Yu-Zhe Zhang, Bing Bai, Yu-Qiang Fang, Xi-Yu Luo, Zi-Ye An, Jun Li, Jun Zhang, Feihu Xu, Xiao-Hui Bao, Jian-Wei Pan
Summary: In this experiment, an atomic-ensemble quantum memory was verified using a measurement-device-independent scheme. A single photon was stored in one atomic ensemble and later retrieved for interference with a second photon for a joint Bell-state measurement. By evaluating correlations between random states and BSM results, the memory's ability to preserve entanglement was confirmed.
PHYSICAL REVIEW LETTERS
(2021)
Article
Medical Laboratory Technology
Wolfgang Huf, Mike Mohns, Zoe Bunning, Rebecca Lister, Tetiana Garmatiuk, Christoph Buchta, Brigitte Ettl
Summary: This study aims to establish a benchmarking method for medical laboratory performance at a high abstraction level, and provides an initial understanding of the current state in Europe, Middle East, and Africa region. The results show the need for stronger integration of laboratories into the clinical care process, as well as improvements in digitalization, automation, and the establishment of quality management systems in laboratory operations.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2022)
Article
Respiratory System
Alice Rossi, Alessandra Bragonzi, Melessike Medede, Ida De Fino, Giuseppe Lippi, Marco Prosdocimi, Anna Tamanini, Giulio Cabrini, Maria Cristina Dechecchi
Summary: We have previously demonstrated that beta-sitosterol (BSS) inhibits the expression of IL-8 in CF bronchial epithelial cells exposed to P. aeruginosa. In this study, we show that BSS significantly reduces leukocyte recruitment and bacterial colonization in the airways of a mouse model with chronic lung infection. BSS treatment also decreases the expression of key cytokines involved in immune response in the lung tissue. Our findings suggest that BSS has the potential to be a new drug for targeting excessive neutrophil recruitment in chronically infected lungs and further investigations on its protective mechanisms are encouraged.
JOURNAL OF CYSTIC FIBROSIS
(2023)
Article
Nutrition & Dietetics
Renata Bortolus, Francesca Filippini, Francesca Chiaffarino, Silvia Udali, Marianna Rinaldi, Giorgio Gandini, Martina Montagnana, Giuseppe Lippi, Oliviero Olivieri, Fabio Parazzini, Simonetta Friso
Summary: This study investigated the iron status of healthy blood donors in Italy and found that a large proportion of the subjects had adequate plasma iron and ferritin concentrations. There was a relationship between folate-related genetic polymorphisms and iron metabolism, which warrants further investigation.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Medical Laboratory Technology
Gian Luca Salvagno, Brandon M. Henry, Giulio Bongiovanni, Simone De Nitto, Laura Pighi, Giuseppe Lippi
Summary: This proof of concept study demonstrates the potential feasibility of using rapid diagnostic tests to gather information on viral load in patients with acute SARS-CoV-2 infection.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Review
Medical Laboratory Technology
Julien Favresse, Jonathan Douxfils, Brandon Henry, Giuseppe Lippi, Mario Plebani
Summary: This review highlights the contribution of the journal Clinical Chemistry and Laboratory Medicine (CCLM) in generating knowledge in SARS-CoV-2 diagnosis, with a special focus on COVID-19 research. It emphasizes the importance of the journal in publishing major guidelines related to COVID-19 and its dedication to helping the field better understand and diagnose this emerging disease.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Medical Laboratory Technology
Giuseppe Lippi, Brandon M. Henry, Mario Plebani
Summary: Due to technical limitations, the diagnostic testing for SARS-CoV-2 mainly relies on antigen rapid diagnostic tests (Ag-RDTs). However, these tests have limited analytical sensitivity and require manual operation, often performed by unskilled personnel or patients themselves, which may significantly impair their accuracy. This article provides an updated overview of the preanalytical drawbacks that may affect the accuracy of SARS-CoV-2 Ag-RDTs.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Medical Laboratory Technology
Wayne J. Dimech, Giuseppe A. Vincini, Mario Plebani, Giuseppe Lippi, James H. Nichols, Oswald Sonntag
Summary: As testing for infectious diseases evolves, the methods for controlling these assays need to change as well. Traditional quality control methods used in clinical chemistry are not suitable for infectious disease serology due to the many differences between the two. This paper outlines these differences and provides recommendations for quality control in infectious disease serology.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Health Care Sciences & Services
Ida J. Korfage, Suzanne Polinder, Nancy Preston, Johannes J. M. van Delden, Sandra A. J. L. M. Geraerds, Lesley Dunleavy, Kristof Faes, Guido Miccinesi, Giulia Carreras, Caroline Moeller Arnfeldt, Marijke C. Kars, Giuseppe Lippi, Urska Lunder, Ceu Mateus, Kristian Pollock, Luc Deliens, Mogens Groenvold, Agnes van der Heide, Judith A. C. Rietjens
Summary: Advance care planning supports patients to reflect on and discuss preferences for future treatment and care. Studies on the impact of advance care planning on healthcare use and costs are limited. The findings of this study suggest that the lower healthcare use and costs observed in the intervention group were mainly attributed to patients' characteristics, and the impact of the intervention itself could not be determined.
PALLIATIVE MEDICINE
(2023)
Letter
Hematology
Giuseppe Lippi, Valeria Perilli
SEMINARS IN THROMBOSIS AND HEMOSTASIS
(2023)
Editorial Material
Medical Laboratory Technology
Giuseppe Lippi, Brandon M. Henry, Julien Favresse, Mario Plebani
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Review
Medical Laboratory Technology
Patryk Ostrowski, Michal Bonczar, Aida-Elena Avram, Giuseppe Lippi, Brandon M. M. Henry
Summary: Skeletal muscle tissue (SKM) can be damaged due to various causes, with drug-induced myopathy being one of the most common. The clinical presentation of drug-induced myopathies can vary greatly, ranging from mild myalgias to severe weakness and rhabdomyolysis. However, current biomarkers for SKM injury lack sensitivity and specificity. This study proposes a strategy for drug safety monitoring using available biomarkers and discusses mechanisms and novel biomarkers for drug-induced SKM injury.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Editorial Material
Medicine, General & Internal
Giuseppe Lippi, Brandon M. Henry
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Oncology
Giulia Turri, Simone Caligola, Stefano Ugel, Cristian Conti, Silvia Zenuni, Valeria Barresi, Andrea Ruzzenente, Giuseppe Lippi, Aldo Scarpa, Vincenzo Bronte, Alfredo Guglielmi, Corrado Pedrazzani
Summary: This study demonstrates that alterations in leukocytes count and neutrophil-to-lymphocyte ratio (NLR) before diagnosis of colorectal cancer (CRC) can predict prognosis and are associated with overall survival and cancer-related survival after surgery.
FRONTIERS IN ONCOLOGY
(2023)
Article
Anesthesiology
Mohammed F. Abosamak, Ivan Szergyuk, Maria Helena Santos de Oliveira, Sara Mathkar Almutairi, Jawza Salem Alharbi, Stefanie W. Benoit, Giuseppe Lippi, Marianna Tovt-Korshynska, Brandon Michael Henry
Summary: According to research, electrolyte abnormalities are common in COVID-19 patients and are associated with adverse outcomes. This study investigated electrolyte imbalances in COVID-19 patients and found that admission levels of electrolytes and changes over the course of ICU stay are associated with mortality.
EGYPTIAN JOURNAL OF ANAESTHESIA
(2023)
Letter
Medical Laboratory Technology
Simone De Nitto, Laura Pighi, Gian Luca Salvagno, Giuseppe Lippi
ADVANCES IN LABORATORY MEDICINE-AVANCES EN MEDICINA DE LABORATORIO
(2023)
Letter
Medicine, General & Internal
Giuseppe Lippi, Fabian Sanchis-Gomar, Brandon M. Henry
POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ
(2023)