Pharmacogenetics of vitamin K antagonists: useful or hype?

A Rapid-ACCE review of CYP2C9 and VKORC1 alleles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding

(2009) Monica R McClain et al.   GENETICS IN MEDICINE

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

Effect of CYP2C9 and VKORC1 genotypes on early-phase and steady-state warfarin dosing in Korean patients with mechanical heart valve replacement

(2009) Ho-Sook Kim et al.   Pharmacogenetics and Genomics

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

(2008) Ulrich M. Zanger et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Genetic Testing for Warfarin Therapy Initiation

(2008) Lauren M Hynicka et al.   ANNALS OF PHARMACOTHERAPY

Azathioprine-Induced Warfarin Resistance

(2008) S. R Vazquez et al.   ANNALS OF PHARMACOTHERAPY

CYP4F2 genetic variant alters required warfarin dose

(2008) M. D. Caldwell et al.   BLOOD

Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement

(2008) D. Wang et al.   BLOOD

The largest prospective warfarin-treated cohort supports genetic forecasting

(2008) M. Wadelius et al.   BLOOD

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

(2008) G. M. Cooper et al.   BLOOD

The story of the discovery of heparin and warfarin

(2008) Douglas Wardrop et al.   BRITISH JOURNAL OF HAEMATOLOGY

Pharmacology and Management of the Vitamin K Antagonists

(2008) Jack Ansell et al.   CHEST

Ethnic Differences in Cardiovascular Drug Response

(2008) Julie A. Johnson   CIRCULATION

The changing scenario in laboratory medicine and the role of laboratory professionals in translational medicine

(2008) Mario Plebani   CLINICA CHIMICA ACTA

Will “personalized medicine” need personalized laboratory approach?

(2008) Gian Cesare Guidi et al.   CLINICA CHIMICA ACTA

SYBR Green-based real-time PCR assay for detection of VKORC1 and CYP2C9 polymorphisms that modulate warfarin dose requirement

(2008) Sheng-Wen Huang et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Clinical Pharmacogenetics and Potential Application in Personalized Medicine

(2008) Shu-Feng Zhou et al.   CURRENT DRUG METABOLISM

Pharmacogenomics of 4-Hydroxycoumarin Anticoagulants

(2008) Nicholas Au et al.   DRUG METABOLISM REVIEWS

VKORC1 and CYP2C9 polymorphisms are associated with warfarin dose requirements in Turkish patients

(2008) G. Oner Ozgon et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

A vitamin K epoxide reductase complex subunit 1 mutation in an Irish patient with warfarin resistance

(2008) F. N. Áinle et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions inVKORC1

(2008) D. J. HARRINGTON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetic Determinants of Response to Warfarin during Initial Anticoagulation

(2008) Ute I. Schwarz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influence ofCYP2C9andVKORC1on warfarin dose, anticoagulation attainment and maintenance among European–Americans and African–Americans

(2008) Nita A Limdi et al.   PHARMACOGENOMICS

Genetic Testing for Warfarin Dosing? Not Yet Ready for Prime Time

(2008) Henry I Bussey et al.   PHARMACOTHERAPY

Incremental parameter evaluation from incomplete data with application to the population pharmacology of anticoagulants

(2008) M. O. Vlad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genotyping method for VKORC1 1173C>T by Pyrosequencing®technology

(2008) Camilla Enström et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Current and Future Prospects for Anticoagulant Therapy: Inhibitors of Factor Xa and Factor IIa

(2008) Job Harenberg et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Survival of Heparins, Oral Anticoagulants, and Aspirin after the Year 2010

(2008) Jawed Fareed et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Patient-Specific Decision-Making for Warfarin Therapy in Nonvalvular Atrial Fibrillation

(2008) Mark H. Eckman et al.   STROKE