Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice

Genetic Determination of Plasma Cholesterol Efflux Capacity Is Gender-Specific and Independent of HDL-Cholesterol Levels

(2013) Elise F. Villard et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin 17A inhibits autophagy through activation of PIK3CA to interrupt the GSK3B-mediated degradation of BCL2 in lung epithelial cells

(2013) Hong Liu et al.   Autophagy

Targeting GGTase-I Activates RHOA, Increases Macrophage Reverse Cholesterol Transport, and Reduces Atherosclerosis in Mice

(2013) Omar M. Khan et al.   CIRCULATION

Posttranscriptional Regulation of ATP-Binding Cassette Transporter A1 in Lipid Metabolism

(2013) Yun-cheng Lv et al.   DNA AND CELL BIOLOGY

BIG1, a Brefeldin A–Inhibited Guanine Nucleotide-Exchange Protein Modulates ATP-Binding Cassette Transporter A-1 Trafficking and Function

(2012) Sisi Lin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice

(2012) Yuan Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Is it time to revise the HDL cholesterol hypothesis?

(2012) Daniel J Rader et al.   NATURE MEDICINE

Effects of Dalcetrapib in Patients with a Recent Acute Coronary Syndrome

(2012) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deleterious impact of elaidic fatty acid on ABCA1-mediated cholesterol efflux from mouse and human macrophages

(2011) Natalie Fournier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Calpain-mediated ABCA1 degradation: Post-translational regulation of ABCA1 for HDL biogenesis

(2011) Shinji Yokoyama et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Pharmacologic Suppression of Hepatic ATP-Binding Cassette Transporter 1 Activity in Mice Reduces High-Density Lipoprotein Cholesterol Levels but Promotes Reverse Cholesterol Transport

(2011) Shigenori Yamamoto et al.   CIRCULATION

Ubiquitination is associated with lysosomal degradation of cell surface-resident ATP-binding cassette transporter A1 (ABCA1) through the endosomal sorting complex required for transport (ESCRT) pathway

(2011) Tadahaya Mizuno et al.   HEPATOLOGY

Beneficial effects of cordycepin on metabolic profiles of liver and plasma from hyperlipidemic hamsters

(2011) Yang Sun et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

The adenosine derivative 2′,3′,5′-tri-O-acetyl-N6-(3-hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo

(2011) Peng Guo et al.   LIFE SCIENCES

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Calmodulin Interacts With ATP Binding Cassette Transporter A1 to Protect From Calpain-Mediated Degradation and Upregulates High-Density Lipoprotein Generation

(2010) Noriyuki Iwamoto et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages

(2010) Margarita de la Llera-Moya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Coffee Consumption Enhances High-Density Lipoprotein-Mediated Cholesterol Efflux in Macrophages

(2010) Harumi Uto-Kondo et al.   CIRCULATION RESEARCH

Adenosine Monophosphate-activated Protein Kinase Induces Cholesterol Efflux from Macrophage-derived Foam Cells and Alleviates Atherosclerosis in Apolipoprotein E-deficient Mice

(2010) Dan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological inhibition of ABCA1 degradation increases HDL biogenesis and exhibits antiatherogenesis

(2009) Reijiro Arakawa et al.   JOURNAL OF LIPID RESEARCH

Update on strategies to increase HDL quantity and function

(2009) Danielle Duffy et al.   Nature Reviews Cardiology

ApoA-I Facilitates ABCA1 Recycle/Accumulation to Cell Surface by Inhibiting Its Intracellular Degradation and Increases HDL Generation

(2008) Rui Lu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY