Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity

Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses

(2015) Zeynep Akgoc et al.   JOURNAL OF LIPID RESEARCH

Sphingolipid transfer proteins defined by the GLTP-fold

(2015) Lucy Malinina et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2

(2014) Vincent O. Oninla et al.   JOURNAL OF LIPID RESEARCH

Gangliosides and Gangliosidoses: Principles of Molecular and Metabolic Pathogenesis

(2013) K. Sandhoff et al.   JOURNAL OF NEUROSCIENCE

How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

(2013) Jacques Fantini et al.   Frontiers in Physiology

Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

(2012) F.-Xabier Contreras et al.   NATURE

Amino acid substitution in NPC1 that abolishes cholesterol binding reproduces phenotype of complete NPC1 deficiency in mice

(2011) X. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosomal Lipid Storage Diseases

(2011) H. Schulze et al.   Cold Spring Harbor Perspectives in Biology

Identification of Surface Residues on Niemann-Pick C2 Essential for Hydrophobic Handoff of Cholesterol to NPC1 in Lysosomes

(2010) Michael L. Wang et al.   Cell Metabolism

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion

(2010) Misbaudeen Abdul-Hammed et al.   JOURNAL OF LIPID RESEARCH

Biological Function of the Cellular Lipid BMP—BMP as a Key Activator for Cholesterol Sorting and Membrane Digestion

(2010) Hichem D. Gallala et al.   NEUROCHEMICAL RESEARCH

Niemann-Pick C disease: Not your average lysosomal storage disease

(2010) E. M. Kaye   NEUROLOGY

Ligand Extraction Properties of the GM2 Activator Protein and Its Interactions with Lipid Vesicles

(2009) Yong Ran et al.   BIOPHYSICAL JOURNAL

Saposin B-dependent Reconstitution of Arylsulfatase A Activityin Vitroand in Cell Culture Models of Metachromatic Leukodystrophy

(2009) Ulrich Matzner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secondary lipid accumulation in lysosomal disease

(2008) Steven U. Walkley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH