Evaluation of HDL-modulating interventions for cardiovascular risk reduction using a systems pharmacology approach

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

(2015) Ruud S. Kootte et al.   JOURNAL OF LIPID RESEARCH

CSL112 Enhances Biomarkers of Reverse Cholesterol Transport After Single and Multiple Infusions in Healthy Subjects

(2014) Andreas Gille et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HDL-targeted therapies: progress, failures and future

(2014) Bronwyn A. Kingwell et al.   NATURE REVIEWS DRUG DISCOVERY

RVX-208, an Inducer of ApoA-I in Humans, Is a BET Bromodomain Antagonist

(2014) Kevin G. McLure et al.   PLoS One

The LDL-HDL Profile Determines the Risk of Atherosclerosis: A Mathematical Model

(2014) Wenrui Hao et al.   PLoS One

An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway

(2014) James Lu et al.   PLoS Computational Biology

A Comparison of the Theoretical Relationship between HDL Size and the Ratio of HDL Cholesterol to Apolipoprotein A-I with Experimental Results from the Women's Health Study

(2013) N. A. Mazer et al.   CLINICAL CHEMISTRY

Anti-PCSK9 therapies for the treatment of hypercholesterolemia

(2012) Amanda J Hooper et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans

(2012) Niek C. A. van de Pas et al.   JOURNAL OF LIPID RESEARCH

Effects of Dalcetrapib in Patients with a Recent Acute Coronary Syndrome

(2012) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of a Novel Oral Inducer of Apolipoprotein A-I Synthesis in Statin-Treated Patients With Stable Coronary Artery Disease

(2011) Stephen J. Nicholls et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

RVX-208

(2010) Dana Bailey et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A First-in-Man, Randomized, Placebo-Controlled Study to Evaluate the Safety and Feasibility of Autologous Delipidated High-Density Lipoprotein Plasma Infusions in Patients With Acute Coronary Syndrome

(2010) Ron Waksman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

(2009) M. J. Chapman et al.   EUROPEAN HEART JOURNAL

Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo

(2009) Frank M. Sacks et al.   JOURNAL OF LIPID RESEARCH

Infusion of Reconstituted High-Density Lipoprotein Leads to Acute Changes in Human Atherosclerotic Plaque

(2008) James A. Shaw et al.   CIRCULATION RESEARCH

Computational Lipidology: Predicting Lipoprotein Density Profiles in Human Blood Plasma

(2008) Katrin Hübner et al.   PLoS Computational Biology