Interferon at the crossroads of allergy and viral infections

Asthma

(2015) Regina K. Rowe et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

The Effect of Inhaled IFN-β on Worsening of Asthma Symptoms Caused by Viral Infections. A Randomized Trial

(2014) Ratko Djukanović et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

How rhinovirus infections cause exacerbations of asthma

(2014) J. E. Gern   CLINICAL AND EXPERIMENTAL ALLERGY

Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children

(2014) Susan V. Lynch et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations

(2014) Kirsten M. Kloepfer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

(2014) N. A. Barrett et al.   JOURNAL OF IMMUNOLOGY

IFN-  Suppresses GATA3 Transcription from a Distal Exon and Promotes H3K27 Trimethylation of the CNS-1 Enhancer in Human Th2 Cells

(2014) J. P. Huber et al.   JOURNAL OF IMMUNOLOGY

Pegylated interferons Lambda-1a and alfa-2a display different gene induction and cytokine and chemokine release profiles in whole blood, human hepatocytes and peripheral blood mononuclear cells

(2014) J. Freeman et al.   JOURNAL OF VIRAL HEPATITIS

Asthma Is Associated with Multiple Alterations in Anti-Viral Innate Signalling Pathways

(2014) Antonia L. Pritchard et al.   PLoS One

Omalizumab in Asthma: An Update on Recent Developments

(2014) Marc Humbert et al.   Journal of Allergy and Clinical Immunology-In Practice

TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.

(2013) K. S. Parsons et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Influenza-Induced Inflammation Drives Pneumococcal Otitis Media

(2013) Kirsty R. Short et al.   INFECTION AND IMMUNITY

Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3

(2013) Ilkka S. Junttila et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation

(2013) Z Su et al.   Mucosal Immunology

Viral and Bacterial Interactions in the Upper Respiratory Tract

(2013) Astrid A. T. M. Bosch et al.   PLoS Pathogens

Changes in serum Interleukin-33 concentration before and after treatment with pegylated interferon alfa-2a plus ribavirin in patients with chronic hepatitis C genotype 1b infection

(2012) Bruno Cacopardo et al.   Hepatitis Monthly

Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children

(2012) Sandy R. Durrani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Rhinovirus 16–induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients

(2012) Annemarie Sykes et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Innate IFNs and Plasmacytoid Dendritic Cells Constrain Th2 Cytokine Responses to Rhinovirus: A Regulatory Mechanism with Relevance to Asthma

(2012) A. L. Pritchard et al.   JOURNAL OF IMMUNOLOGY

Type III IFNs Are Produced by and Stimulate Human Plasmacytoid Dendritic Cells

(2012) Z. Yin et al.   JOURNAL OF IMMUNOLOGY

IL-25 drives remodelling in allergic airways disease induced by house dust mite

(2012) Lisa G Gregory et al.   THORAX

Targeting IgE in asthma

(2011) Kristin Kuhl et al.   CURRENT OPINION IN PULMONARY MEDICINE

Rhinoviruses, allergic inflammation, and asthma

(2011) Monica L. Gavala et al.   IMMUNOLOGICAL REVIEWS

Regulation of effector and memory T-cell functions by type I interferon

(2011) Jonathan P. Huber et al.   IMMUNOLOGY

Use of pegylated interferon in hypereosinophilic syndrome

(2011) Joseph H. Butterfield et al.   LEUKEMIA RESEARCH

Cutting Edge: Type I IFN Reverses Human Th2 Commitment and Stability by Suppressing GATA3

(2010) J. P. Huber et al.   JOURNAL OF IMMUNOLOGY

Counterregulation between the Fc RI Pathway and Antiviral Responses in Human Plasmacytoid Dendritic Cells

(2010) M. A. Gill et al.   JOURNAL OF IMMUNOLOGY

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

(2010) Hua-Chen Chang et al.   NATURE IMMUNOLOGY

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-  in bronchial epithelial cells from donors with asthma

(2010) L. Uller et al.   THORAX

Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells

(2009) M. R. Khaitov et al.   ALLERGY

IFN- 1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells

(2009) J. Dai et al.   BLOOD

Toll-like receptor 7 function is reduced in adolescents with asthma

(2009) M. Roponen et al.   EUROPEAN RESPIRATORY JOURNAL

Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines

(2009) K Witte et al.   GENES AND IMMUNITY

Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung

(2009) Christina C. Lewis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects

(2009) Nilceia Lopez-Souza et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

IFN-  Inhibits Human Th17 Cell Differentiation

(2009) V. S. Ramgolam et al.   JOURNAL OF IMMUNOLOGY

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma

(2009) Y A Bochkov et al.   Mucosal Immunology

The Presence of Rhinovirus in Lower Airways of Patients with Bronchial Asthma

(2008) Monika Woś et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Interferon-alpha controls IL-17 expression in vitro and in vivo

(2008) Alexander R. Moschen et al.   IMMUNOBIOLOGY

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE