4.5 Article

Prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults

Journal

CLINICAL BIOCHEMISTRY
Volume 43, Issue 18, Pages 1431-1435

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.clinbiochem.2010.09.022

Keywords

Vitamin D deficiency; Adult; Prevalence; Musculoskeletal disease; Chronic disease

Funding

  1. University Research Council (URC) of AKU
  2. URC (University Research Council)

Ask authors/readers for more resources

Objective: This study aims to determine the prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults. Design and methods: A total of 123 subjects, 56.9% males and 43.1% females, were recruited from a tertiary care hospital in Karachi, Pakistan. Questionnaires were administered to gather demographics; height, weight, and blood samples were also taken. For staging serum 25OHD, the cutoff values <= 50 nmol/L and 50.1-74.9 nmol/L were defined as deficiency and insufficiency, respectively. Results: The mean vitamin D level in the study subjects was 41.1 +/- 9.6 nmol/L. Of them, 90% had low serum 25OHD levels: 69.9% were deficient and 21.1% had insufficient levels of 25OHD. There was a significant negative correlation between serum 25OHD and iPTH levels. Conclusion: The high prevalence of vitamin D deficiency and insufficiency showed that a high proportion of apparently healthy adults are at risk of developing musculoskeletal and other chronic diseases. Serum iPTH and serum 25OHD levels are better markers of this deficiency as compared to other markers. (C) 2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Engineering, Environmental

Risk assessment for arsenic-contaminated groundwater along River Indus in Pakistan

Unaib Rabbani, Gohar Mahar, Azhar Siddique, Zafar Fatmi

ENVIRONMENTAL GEOCHEMISTRY AND HEALTH (2017)

Article Public, Environmental & Occupational Health

Multimorbidity in South Asian adults: prevalence, risk factors and mortality

Kalpana Singh, Shivani A. Patel, Suddhendu Biswas, Roopa Shivashankar, Dimple Kondal, Vamadevan S. Ajay, Ranjit Mohan Anjana, Zafar Fatmi, Mohammed K. Ali, M. Masood Kadir, Viswanathan Mohan, Nikhil Tandon, K. M. Venkat Narayan, Dorairaj Prabhakaran

JOURNAL OF PUBLIC HEALTH (2019)

Article Environmental Sciences

PM2.5 in a megacity of Asia (Karachi): Source apportionment and health effects

Kelly Lurie, Shedrack R. Nayebare, Zafar Fatmi, David O. Carpenter, Azhar Siddique, Daniel Malashock, Kamran Khan, Jahan Zeb, Mirza M. Hussain, Fida Khatib, Haider A. Khwaja

ATMOSPHERIC ENVIRONMENT (2019)

Article Respiratory System

Epidemiology of asthma and associated factors in an urban Pakistani population: adult asthma study-Karachi

Shama Razzaq, Asaad Ahmed Nafees, Unaib Rabbani, Muhammad Irfan, Shahla Naeem, Muhammad Arslan Khan, Zafar Fatmi, Peter Burney

BMC PULMONARY MEDICINE (2018)

Article Medicine, General & Internal

Coronary heart disease, hypertension and use of biomass fuel among women: comparative cross-sectional study

Zafar Fatmi, Georgia Ntani, David Coggon

BMJ OPEN (2019)

Article Environmental Sciences

Levels and Determinants of Fine Particulate Matter and Carbon Monoxide in Kitchens Using Biomass and Non-Biomass Fuel for Cooking

Zafar Fatmi, Georgia Ntani, David Coggon

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

Article Neurosciences

Exploring the Relationship Between Air Quality and Ischemic Stroke Admissions During the COVID-19 Pandemic

Sajid Hameed, Maria Khan, Zafar Fatmi, Mohammad Wasay

Summary: The study revealed a significant drop in air quality index and a decrease of over 50% in the number of stroke admissions at a major tertiary hospital in Karachi during the lockdown period. The authors hypothesize that the reduction in stroke admissions may be due to an actual decrease in stroke incidence resulting from the improvement in air quality.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2021)

Article Public, Environmental & Occupational Health

Pesticides Use and Impaired Lung Function Among Male Agricultural Farmers in Rural Sindh, Pakistan

Zahid Hyder Wadani, Iqbal Azam, Muhammad Irfan, Zafar Fatmi

Summary: Pesticide use was found to be associated with a nearly doubled risk of both restrictive and obstructive lung dysfunction with each increasing year of exposure to pesticides. Reliable monitoring and reporting procedures, along with appropriate environmental policies and regulations for pesticide handling, are needed. Interventional studies should be conducted to train farmers on the proper use of personal protective equipment to limit pesticide exposure.

ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH (2022)

Article Medicine, General & Internal

Understanding the mental health impact and needs of public healthcare professionals during COVID-19 in Pakistan : a qualitative study

Waqas Hameed, Anam Shahil Feroz, Bilal Iqbal Avan, Bushra Khan, Zafar Fatmi, Noreen Afzal, Hussain Jafri, Mansoor Ali Wassan, Sameen Siddiqi

Summary: This study explores the mental health impact and needs of public sector healthcare workers in Pakistan during the COVID-19 pandemic. The study identifies the fear of infection, social isolation, and excessive workload as key factors affecting the mental health of healthcare professionals. The study also highlights the need for counselling services, safe working conditions, and appreciation and motivation for healthcare professionals in order to address their mental health needs.

BMJ OPEN (2022)

Article Medicine, General & Internal

Impact of COVID-19 on mental health of primary healthcare workers in Pakistan: lessons from a qualitative inquiry

Waqas Hameed, Bilal Iqbal Avan, Anam Shahil Feroz, Bushra Khan, Zafar Fatmi, Hussain Jafri, Mansoor Ali Wassan, Sameen Siddiqi

Summary: This study explored the mental health impact of COVID-19 on primary healthcare workers and sought suggestions and recommendations to address their mental health needs. Interviews revealed that there was fear, stress, and anxiety among healthcare workers due to lack of information, false rumors, and inadequate personal protective measures. Training, provision of personal protective equipment, and emotional support from coworkers were found to be effective in addressing their mental health needs. The study also highlighted the importance of appreciation, recognition, and psychosocial support from mental health professionals.

BMJ OPEN (2022)

Article Health Care Sciences & Services

We Won't Go There: Barriers to Accessing Maternal and Newborn Care in District Thatta, Pakistan

Muhammad Asim, Sarah Saleem, Zarak Husain Ahmed, Imran Naeem, Farina Abrejo, Zafar Fatmi, Sameen Siddiqi

Summary: This study in Thatta, Sindh, Pakistan explores the multifaceted barriers inhibiting women from seeking maternal and newborn health care, including individual distrust, inadequate symptom recognition, aversion to biomedical interventions, and expensive transportation services. Capacity development, health awareness, and structural interventions are recommended to address these barriers and reduce maternal and neonatal mortality.

HEALTHCARE (2021)

Article Criminology & Penology

Prevalence of Emotional and Physical Intimate Partner Violence Among Married Women in Pakistan

Meesha Iqbal, Zafar Fatmi

Summary: Intimate partner violence (IPV) is prevalent in Pakistan, with emotional violence at 36.4% and physical violence at 18.4%. Factors such as husband's age, alcohol intake, and educational status are associated with emotional and physical violence. Further studies are needed to explore underlying factors and regional variations for effective interventions.

JOURNAL OF INTERPERSONAL VIOLENCE (2021)

Article Public, Environmental & Occupational Health

Building global partnerships through shared curricula for an MPH programme in India and Sri Lanka

Nalini Sathiakumar, Meghan Tipre, Rajitha Wickremasinghe, Vinod Bhat, Muhammad Masood Kadir, David Coggon, Arunasalem Pathemeswaran, Ramachandra Kamath, G. Arunkumar, Zafar Fatmi, Tamika L. Smith, Sanjay M. Pattanshetty, Elizabeth Delzell

GLOBAL PUBLIC HEALTH (2019)

Article Public, Environmental & Occupational Health

Dose-response of Cotton Dust Exposure with Lung Function among Textile Workers: MultiTex Study in Karachi, Pakistan

Naureen Akber Ali, Asaad Ahmed Nafees, Zafar Fatmi, Syed Iqbal Azam

INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2018)

Article Health Care Sciences & Services

Inequities in Antenatal Care, and Individual and Environmental Determinants of Utilization at National and Sub-national Level in Pakistan: A Multilevel Analysis

Ambreen Sahito, Zafar Fatmi

INTERNATIONAL JOURNAL OF HEALTH POLICY AND MANAGEMENT (2018)

No Data Available