3.9 Article

Expression of Interleukin-5 and Tumor Necrosis Factor Alpha in Cervical Carcinoma

Journal

CLINICAL AND VACCINE IMMUNOLOGY
Volume 16, Issue 6, Pages 959-961

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00262-08

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Funding

  1. Brain Korea 21 Project for Medical Sciences, Yonsei University
  2. Korean Health 21 RD Project
  3. Ministry of Health & Welfare, Republic of Korea [0412CR01-0704-0001]

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Interleukin-5 (IL-5) levels were significantly higher in vaginal washing fluids from patients with cervical carcinoma than in those from patients with carcinoma in situ and controls. Tumor necrosis factor alpha levels did not differ among the three groups. Detection of IL-5 in cervical secretions may be a useful marker for evaluating aggressive local immune response in cervical carcinoma.

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