Experimental models to investigate the function of dendritic cell subsets: challenges and implications

CD11c+CD11b+ Dendritic Cells Play an Important Role in Intravenous Tolerance and the Suppression of Experimental Autoimmune Encephalomyelitis

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Epidermal and Dermal Dendritic Cells Display Differential Activation and Migratory Behavior While Sharing the Ability to Stimulate CD4+ T Cell Proliferation In Vivo

(2014) E. Shklovskaya et al.   JOURNAL OF IMMUNOLOGY

Characterization of resident and migratory dendritic cells in human lymph nodes

(2012) Elodie Segura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerhans Cells Require MyD88-Dependent Signals for Candida albicans Response but Not for Contact Hypersensitivity or Migration

(2012) K. Haley et al.   JOURNAL OF IMMUNOLOGY

Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice

(2012) André P Tittel et al.   NATURE METHODS

Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

(2012) T. Fukaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation

(2011) R. van de Ven et al.   BLOOD

TLR7 enables cross-presentation by multiple dendritic cell subsets through a type I IFN-dependent pathway

(2011) J. Z. Oh et al.   BLOOD

Id2 expression delineates differential checkpoints in the genetic program of CD8α+and CD103+dendritic cell lineages

(2011) Jacob T Jackson et al.   EMBO JOURNAL

CD8α+and CD8α−DC subsets from BCG-infected mice inhibit allergic Th2-cell responses by enhancing Th1-cell and Treg-cell activity respectively

(2011) Xiaoling Gao et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Skin-Resident Murine Dendritic Cell Subsets Promote Distinct and Opposing Antigen-Specific T Helper Cell Responses

(2011) Botond Z. Igyártó et al.   IMMUNITY

The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

(2011) Mirjam Kool et al.   IMMUNITY

Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: Mechanisms and biomedical applications

(2011) Iván D. Mascanfroni et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype

(2011) M. H. Lahoud et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell-associated lectin 2 (DCAL2) defines a distinct CD8α− dendritic cell subset

(2011) Shinji Kasahara et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pulmonary CD103+ dendritic cells prime Th2 responses to inhaled allergens

(2011) H Nakano et al.   Mucosal Immunology

Batf3-Dependent CD11blow/− Peripheral Dendritic Cells Are GM-CSF-Independent and Are Not Required for Th Cell Priming after Subcutaneous Immunization

(2011) Brian T. Edelson et al.   PLoS One

Langerhans cells are precommitted to immune tolerance induction

(2011) E. Shklovskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells

(2011) K. Baker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

A novel in vivo inducible dendritic cell ablation model in mice

(2010) Megumi Okuyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous dendritic cells mediate the effects of intravenously injected therapeutic immunosuppressive dendritic cells in transplantation

(2010) S. J. Divito et al.   BLOOD

Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells

(2010) Natalio Garbi et al.   CURRENT OPINION IN IMMUNOLOGY

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A

(2010) Olivier P. Joffre et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations

(2010) Neil A. Mabbott et al.   IMMUNOBIOLOGY

Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets

(2010) Karine Crozat et al.   IMMUNOLOGICAL REVIEWS

Mechanisms regulating dendritic cell specification and development

(2010) Stephanie S. Watowich et al.   IMMUNOLOGICAL REVIEWS

Defining dendritic cells by conditional and constitutive cell ablation

(2010) Liat Bar-On et al.   IMMUNOLOGICAL REVIEWS

DC subsets in positive and negative regulation of immunity

(2010) Caroline Coquerelle et al.   IMMUNOLOGICAL REVIEWS

Subsets of migrating intestinal dendritic cells

(2010) Simon Milling et al.   IMMUNOLOGICAL REVIEWS

Features of the dendritic cell lineage

(2010) Ralph M. Steinman et al.   IMMUNOLOGICAL REVIEWS

Found in translation: the human equivalent of mouse CD8+dendritic cells: Table I.

(2010) Jose A. Villadangos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

(2010) Jessica A. Melillo et al.   JOURNAL OF IMMUNOLOGY

Route of Antigen Uptake Differentially Impacts Presentation by Dendritic Cells and Activated Monocytes

(2010) A. O. Kamphorst et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Support Homeostatic Expansion of Foxp3 + Regulatory T Cells in Foxp3.LuciDTR Mice

(2010) Janine Suffner et al.   JOURNAL OF IMMUNOLOGY

Applications of myeloid-specific promoters in transgenic mice support in vivo imaging and functional genomics but do not support the concept of distinct macrophage and dendritic cell lineages or roles in immunity

(2010) D. A. Hume   JOURNAL OF LEUKOCYTE BIOLOGY

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+ T cell responses to influenza

(2010) André Ballesteros-Tato et al.   NATURE IMMUNOLOGY

CD8+ T Cell Priming by Dendritic Cell Vaccines Requires Antigen Transfer to Endogenous Antigen Presenting Cells

(2010) Alice W. Yewdall et al.   PLoS One

Lymphoid tissue-specific homing of bone marrow-derived dendritic cells

(2009) R. J. Creusot et al.   BLOOD

A role for CD47 in the development of experimental colitis mediated by SIRPα+CD103−dendritic cells

(2009) Genevieve Fortin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerin+CD8 + Dendritic Cells Are Critical for Cross-Priming and IL-12 Production in Response to Systemic Antigens

(2009) K. J. Farrand et al.   JOURNAL OF IMMUNOLOGY

In Situ-Targeting of Dendritic Cells with Donor-Derived Apoptotic Cells Restrains Indirect Allorecognition and Ameliorates Allograft Vasculopathy

(2009) Zhiliang Wang et al.   PLoS One

Distinctive localization of antigen-presenting cells in human lymph nodes

(2008) C. E. Angel et al.   BLOOD

CD8– dendritic cells preferentially cross-presentSaccharomyces cerevisiae antigens

(2008) Ronald Backer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lack of Conventional Dendritic Cells Is Compatible with Normal Development and T Cell Homeostasis, but Causes Myeloid Proliferative Syndrome

(2008) Tal Birnberg et al.   IMMUNITY

Migratory and Lymphoid-Resident Dendritic Cells Cooperate to Efficiently Prime Naive CD4 T cells

(2008) Eric J. Allenspach et al.   IMMUNITY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

(2008) Satoshi Uematsu et al.   NATURE IMMUNOLOGY

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

(2008) M. L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE