Down syndrome, autoimmunity and T regulatory cells

A Function for IL-7R for CD4+CD25+Foxp3+ T Regulatory Cells

(2014) A. L. Bayer et al.   JOURNAL OF IMMUNOLOGY

Infections and immunodeficiency in Down syndrome

(2011) G. Ram et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Thymus, innate immunity and autoimmune arthritis: Interplay of gene and environment

(2011) Shimon Sakaguchi et al.   FEBS LETTERS

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

Low-dose IL-2 as a therapeutic agent for tolerance induction

(2011) Thomas R Malek et al.   Immunotherapy

Forkhead box protein 3 (FOXP3) mutations lead to increased TH17 cell numbers and regulatory T-cell instability

(2011) Laura Passerini et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interpreting low T-cell receptor excision circles in newborns with DiGeorge anomaly: Importance of assessing naive T-cell markers

(2011) Alan P. Knutsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Killer Treg restore immune homeostasis and suppress autoimmune diabetes in prediabetic NOD mice

(2011) Ayelet Kaminitz et al.   JOURNAL OF AUTOIMMUNITY

Decreased Thymic Output Accounts for Decreased Naive T Cell Numbers in Children with Down Syndrome

(2011) Beatrijs L. P. Bloemers et al.   JOURNAL OF IMMUNOLOGY

Microbial Infection-Induced Expansion of Effector T Cells Overcomes the Suppressive Effects of Regulatory T Cells via an IL-2 Deprivation Mechanism

(2011) A. Benson et al.   JOURNAL OF IMMUNOLOGY

Defect of regulatory T cells in patients with Omenn syndrome

(2010) Barbara Cassani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

CD4 + CD25 + Foxp3 + T Regulatory Cells with Limited TCR Diversity in Control of Autoimmunity

(2009) Dennis Adeegbe et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

Genotype–phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

(2008) Robert Lyle et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Homeostatic Cytokines and Expansion of Regulatory T Cells Accompany Thymic Impairment in Children with Down Syndrome

(2008) Erika Roat et al.   REJUVENATION RESEARCH