Article
Fisheries
Hua Rong, Haoran Zhang, Lijun Ning, Kun Wu, Samwel Mchele Limbu, Qingchao Shi, Chuanjie Qin, Xiaobo Wen
Summary: This study investigated the effects of dietary Pro supplementation on collagen synthesis and deposition in the swim bladder of Chu's croaker. It was found that an optimal Pro supplementation level of 19.36 g kg(-1) significantly increased collagen content. The TGF-beta/Smad signaling pathway played a crucial role in regulating collagen synthesis and deposition in the swim bladder.
Article
Immunology
Fanli Yi, Jing Hu, Xiaoyan Zhu, Yue Wang, Qiuju Yu, Jing Deng, Xuedong Huang, Ying Ma, Yi Xie
Summary: This study utilized RNA-Seq to analyze PPE57-stimulated PBMCs, identifying 1367 DEGs with 685 up-regulated and 682 down-regulated genes after 6 hours of exposure. The type I IFN signaling pathway was found to be significantly enriched, with 14 DEGs identified. Further research on these DEGs and type I IFN signaling in the context of MTB infection is necessary for a more comprehensive understanding of the underlying mechanisms.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Infectious Diseases
Yulei Zhao, Danmin Liu
Summary: The study found that ISGs were upregulated in patients with secondary syphilis, which have diagnostic value for distinguishing syphilis patients from healthy individuals.
INFECTION GENETICS AND EVOLUTION
(2021)
Article
Cell & Tissue Engineering
Vaijayanti Kale
Summary: This study investigates the regulatory mechanism of TGF beta 1 secretion by bone marrow cells in response to erythropoietin, revealing that neutrophils negatively regulate this process by secreting EPO-R.
STEM CELL REVIEWS AND REPORTS
(2022)
Article
Nutrition & Dietetics
Lina Nurbaiti, Nurpudji Astuti Taslim, Agussalim Bukhari, Mochammad Hatta
Summary: This study compared the expression of TGF-01 mRNA and TGF-01 concentrations in stunted and non-stunted toddlers, and linked the nutritional status to the issue of stunting. The results showed significantly lower TGF-01 gene mRNA expression and serum TGF-01 concentrations in stunted toddlers compared to non-stunted toddlers.
CLINICAL NUTRITION ESPEN
(2022)
Article
Chemistry, Medicinal
T. Pavlik, T. A. Fedotcheva, N. G. Gusein-zade, N. L. Shimanovsky
Summary: The combined effects of cold-plasma-treated solution of doxorubicin and MPA on TGF-beta production were studied, indicating a dual effect of hydrogen peroxide and nitrite ions formed in the solution. Short treatment decreased the effects, while longer treatment enhanced the effects of the drugs.
PHARMACEUTICAL CHEMISTRY JOURNAL
(2022)
