4.6 Article

Daily Serial Hemodynamic Data During Pregnancy and Seasonal Variation: The BOSHI Study

Journal

CLINICAL AND EXPERIMENTAL HYPERTENSION
Volume 34, Issue 4, Pages 290-296

Publisher

TAYLOR & FRANCIS INC
DOI: 10.3109/10641963.2012.681086

Keywords

clinical science; blood pressure measurement/monitoring; preeclampsia/pregnancy; self-monitoring of blood pressure

Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology of Japan [18590587, 18390192, 21390201, 22890017, 23590771]
  2. Ministry of Health, Labor and Welfare, Japan [H21-Junkankitou[Seishuu]-Ippan-004]
  3. Japan Society for the Promotion of Science (JSPS) [19.7152, 20.7198, 20.7477, 20.54043]
  4. Takeda Science Foundation
  5. Grants-in-Aid for Scientific Research [23659513, 18390192, 21390201, 22890017, 23590771, 18590587] Funding Source: KAKEN

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Although there are some reports that low plasma volume or increased cardiac output is associated with developing preeclampsia, there are few reports of daily serial hemodynamic data during pregnancy. A total of 37 092 home blood pressure (BP) and heart rate (HR) measurements were obtained from 425 normal pregnant women. Heart rate and shock index (SI) gradually increased by gestational week 32 and then decreased, whereas double product (DP) increased linearly during pregnancy. Although systolic BP and DP were consistently and negatively correlated with daily minimum outside temperature, HR and SI were positively correlated with minimum outside temperature in summer.

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