Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response

Abacavir induces loading of novel self-peptides into HLA-B*57

(2012) Michael A. Norcross et al.   AIDS

Starting dose is a risk factor for allopurinol hypersensitivity syndrome: A proposed safe starting dose of allopurinol

(2012) Lisa K. Stamp et al.   ARTHRITIS AND RHEUMATISM

Avidity determines T-cell reactivity in abacavir hypersensitivity

(2012) Jacqueline Adam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

(2012) D. A. Ostrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia

(2012) Dinesh Khanna et al.   ARTHRITIS CARE & RESEARCH

Allopurinol reduces antigen-specific and polyclonal activation of human T cells

(2012) Damián Pérez-Mazliah et al.   Frontiers in Immunology

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome

(2011) Tai-Ming Ko et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Safety and Efficacy of Febuxostat Treatment in Subjects with Gout and Severe Allopurinol Adverse Reactions

(2011) S. CHOHAN   JOURNAL OF RHEUMATOLOGY

HLA-B58 can help the clinical decision on starting allopurinol in patients with chronic renal insufficiency

(2011) J.-W. Jung et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment

(2010) Lisa K. Stamp et al.   ARTHRITIS AND RHEUMATISM

Cross-Reactivity in Drug Hypersensitivity Reactions to Sulfasalazine and Sulfamethoxazole

(2010) Anna Zawodniak et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Pharmacogenetics of drug hypersensitivity

(2010) Elizabeth J Phillips et al.   PHARMACOGENOMICS

A European study of HLA-B in Stevens???Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

(2008) Christine Lonjou et al.   Pharmacogenetics and Genomics

Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and Israel

(2007) Sima Halevy et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY