Severe asthma: from characteristics to phenotypes to endotypes

Omalizumab in Severe Allergic Asthma Inadequately Controlled With Standard Therapy

(2013) Nicola A. Hanania et al.   ANNALS OF INTERNAL MEDICINE

Allergic bronchopulmonary aspergillosis and omalizumab

(2011) I. Tillie-Leblond et al.   ALLERGY

Multi-symptom asthma as an indication of disease severity in epidemiology

(2011) L. Ekerljung et al.   EUROPEAN RESPIRATORY JOURNAL

Identifying adult asthma phenotypes using a clustering approach

(2011) V. Siroux et al.   EUROPEAN RESPIRATORY JOURNAL

Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation

(2011) Anne E. Dixon et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples

(2011) Katherine J. Baines et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome

(2011) Jan Lötvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TNF-  from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

(2011) M. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma

(2010) Gail M. Gauvreau et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A sequence variant on 17q21 is associated with age at onset and severity of asthma

(2010) Eva Halapi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure toAspergillus fumigatusConidia

(2010) Benjamin J. Murdock et al.   INFECTION AND IMMUNITY

Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision

(2010) Jan L. Brożek et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

(2010) Jean Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis

(2010) James L. Kreindler et al.   JOURNAL OF CLINICAL INVESTIGATION

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort study

(2010) M. Scott et al.   THORAX

Interleukin-13–induced MUC5AC Is Regulated by 15-Lipoxygenase 1 Pathway in Human Bronchial Epithelial Cells

(2009) Jinming Zhao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Qualitative Analysis of High-Resolution CT Scans in Severe Asthma

(2009) Sumit Gupta et al.   CHEST

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

(2009) Pranabashis Haldar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia

(2009) Parameswaran Nair et al.   NEW ENGLAND JOURNAL OF MEDICINE

Add-on omalizumab improves day-to-day symptoms in inadequately controlled severe persistent allergic asthma

(2008) M. Humbert et al.   ALLERGY

Cluster Analysis and Clinical Asthma Phenotypes

(2008) Pranab Haldar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Randomized Controlled Trial of Oral Antifungal Treatment for Severe Asthma with Fungal Sensitization

(2008) David W. Denning et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Multivariate Analysis of Risk Factors for the Air-Trapping Asthmatic Phenotype as Measured by Quantitative CT Analysis

(2008) Ashley Busacker et al.   CHEST

Increased sputum and bronchial biopsy IL-13 expression in severe asthma

(2008) Shironjit K. Saha et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

(2008) Gary P Anderson   LANCET

Gene Expression Profiling of Nasal Polyps Associated With Chronic Sinusitis and Aspirin-Sensitive Asthma

(2008) Konstantina M. Stankovic et al.   LARYNGOSCOPE

Clarithromycin Targets Neutrophilic Airway Inflammation in Refractory Asthma

(2007) Jodie L. Simpson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic fibrosis

(2007) P. Latzin et al.   EUROPEAN RESPIRATORY JOURNAL