Basic mechanisms of itch

Plant cysteine proteases that evoke itch activate protease-activated receptors

(2010) V.B. Reddy et al.   BRITISH JOURNAL OF DERMATOLOGY

Signal transduction by protease-activated receptors

(2010) Unice JK Soh et al.   BRITISH JOURNAL OF PHARMACOLOGY

The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice

(2010) Robson Costa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lysophosphatidic Acid Is a Potential Mediator of Cholestatic Pruritus

(2010) Andreas E. Kremer et al.   GASTROENTEROLOGY

Chloroquine-induced Pruritus

(2010) SE Aghahowa et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis

(2010) Stefanie Haas et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Cathepsin S Elicits Itch and Signals via Protease-Activated Receptors

(2010) Vemuri B. Reddy et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Responsiveness of C Neurons in Rat Dorsal Root Ganglion to 5-Hydroxytryptamine-Induced Pruritic Stimuli In Vivo

(2010) Junichi Hachisuka et al.   JOURNAL OF NEUROPHYSIOLOGY

Protease Activated Receptors 1 and 4 Sensitize TRPV1 in Nociceptive Neurones

(2010) Vittorio Vellani et al.   Molecular Pain

Toll-like receptor 7 mediates pruritus

(2010) Tong Liu et al.   NATURE NEUROSCIENCE

VGLUT2-Dependent Glutamate Release from Nociceptors Is Required to Sense Pain and Suppress Itch

(2010) Yang Liu et al.   NEURON

An Itch To Be Scratched

(2010) Kush N. Patel et al.   NEURON

Aprepitant against pruritus in patients with solid tumours

(2010) Bruno Vincenzi et al.   SUPPORTIVE CARE IN CANCER

Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis

(2010) Sang Eun Lee et al.   YONSEI MEDICAL JOURNAL

Mite serine protease activates protease-activated receptor-2 and induces cytokine release in human keratinocytes

(2009) T. Kato et al.   ALLERGY

Temperature modulated histamine-itch in lesional and nonlesional skin in atopic eczema – a combined psychophysical and neuroimaging study

(2009) F. Pfab et al.   ALLERGY

Distinct patterns of brain activity evoked by histamine-induced itch reveal an association with itch intensity and disease severity in atopic dermatitis

(2009) Y. Ishiuji et al.   BRITISH JOURNAL OF DERMATOLOGY

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

(2009) Qin Liu et al.   CELL

Contemporary Challenges in Mastocytosis

(2009) H. David Pettigrew et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Induction of leukotriene B4 and prostaglandin E2 release from keratinocytes by protease-activated receptor-2-activating peptide in ICR mice

(2009) Yu Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Histamine H4 Receptor Mediates Inflammation and Pruritus in Th2-Dependent Dermal Inflammation

(2009) Jeffery M. Cowden et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Neuroselective transcutaneous electrical stimulation reveals neuronal sensitization in atopic dermatitis

(2009) Maki Ozawa et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist

(2009) Katsunori Yamaura et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Skin problems in chronic kidney disease

(2009) Dirk RJ Kuypers   Nature Reviews Nephrology

The cutaneous sensory system

(2009) Francis McGlone et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localization of histamine H4 receptors in the central nervous system of human and rat

(2008) Marina I. Strakhova et al.   BRAIN RESEARCH

Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice

(2008) R Costa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structures and biological functions of IL-31 and IL-31 receptors

(2008) Qing Zhang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Neuropathic and psychogenic itch

(2008) Gil Yosipovitch et al.   Dermatologic Therapy

Significant differences in central imaging of histamine-induced itch between atopic dermatitis and healthy subjects

(2008) Gudrun Schneider et al.   EUROPEAN JOURNAL OF PAIN

Quantitative analysis of nerve growth factor (NGF) in the atopic dermatitis and psoriasis horny layer and effect of treatment on NGF in atopic dermatitis

(2008) Junko Yamaguchi et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Separate Peripheral Pathways for Pruritus in Man

(2008) Barbara Namer et al.   JOURNAL OF NEUROPHYSIOLOGY

A Role for Polymodal C-Fiber Afferents in Nonhistaminergic Itch

(2008) L. M. Johanek et al.   JOURNAL OF NEUROSCIENCE

Activation of Proteinase-Activated Receptors Induces Itch-Associated Response Through Histamine-Dependent and -Independent Pathways in Mice

(2008) Kenichiro Tsujii et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Histamine-Induced Itch and its Relationship with Pain

(2008) Won-Sik Shim et al.   Molecular Pain

Itch and pain

(2008) Martin Schmelz   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Disease mechanisms in neuropathic itch

(2008) Andreas Binder et al.   Nature clinical practice. Neurology

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

(2007) Kristina Stefansson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY