Why could passive Immunoglobulin E antibody therapy be safe in clinical oncology?

Taking immunogenicity assessment of therapeutic proteins to the next level

(2011) I.C. Büttel et al.   BIOLOGICALS

Trastuzumab Has Preferential Activity against Breast Cancers Driven by HER2 Homodimers

(2011) R. Ghosh et al.   CANCER RESEARCH

Diagnosis and management of drug hypersensitivity reactions

(2011) Antonino Romano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing

(2011) S. Lohse et al.   JOURNAL OF IMMUNOLOGY

Human Eosinophils Exert TNF-  and Granzyme A-Mediated Tumoricidal Activity toward Colon Carcinoma Cells

(2010) F. Legrand et al.   JOURNAL OF IMMUNOLOGY

New challenges to medicare beneficiary access to mAbs

(2010) Joshua Cohen et al.   mAbs

Safety and tolerability of omalizumab

(2009) J. Corren et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Fine epitope mapping of humanized anti-IgE monoclonal antibody omalizumab

(2008) Lei Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells

(2008) Panagiotis Karagiannis et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Antibody-Based Therapy for Solid Tumors

(2008) Li Yan et al.   CANCER JOURNAL

Immunoglobulin E antibodies from pancreatic cancer patients mediate antibody-dependent cell-mediated cytotoxicity against pancreatic cancer cells

(2008) S. L. Fu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interaction of antibodies with ErbB receptor extracellular regions

(2008) Karl R. Schmitz et al.   EXPERIMENTAL CELL RESEARCH

The Ectodomain Shedding of E-cadherin by ADAM15 Supports ErbB Receptor Activation

(2008) Abdo J. Najy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development trends for new cancer therapeutics and vaccines

(2007) J REICHERT   DRUG DISCOVERY TODAY