Article
Medicine, General & Internal
Sang-Hwa Lee, Jong-Ho Kim, Young-Suk Kwon, Jong-Hee Sohn
Summary: The study found that peripheral inflammatory markers (PIMs) significantly increased during migraine attacks, indicating that inflammation may play a role in migraines. Among different markers, NLR and NMR had poor ability to differentiate between migraine and non-migraine headaches, but performed well in distinguishing migraines from other types of headaches.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Tetsuya Akaishi, Tatsuro Misu, Kazuo Fujihara, Naoki Nakaya, Tomohiro Nakamura, Mana Kogure, Rieko Hatanaka, Fumi Itabashi, Ikumi Kanno, Toshiyuki Takahashi, Hiroshi Kuroda, Juichi Fujimori, Yoshiki Takai, Shuhei Nishiyama, Kimihiko Kaneko, Tadashi Ishii, Masashi Aoki, Ichiro Nakashima, Atsushi Hozawa
Summary: Patients with multiple sclerosis showed elevated counts of total white blood cells, monocytes, basophils, and neutrophils at the time of diagnosis. However, the clinical relevance of these biomarkers in the context of the development and progression of MS remains unclear.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Ahmed Mohammed Shumilah, Arwa Mohammed Othman, Anwar Kasim Al-Madhagi
Summary: Inflammation plays a key role in atherosclerosis and ACS. NLR was found to be the strongest predictive marker of ACS, indicating its potential as an auxiliary biomarker in ACS diagnosis.
BMC CARDIOVASCULAR DISORDERS
(2021)
Article
Medicine, General & Internal
Ewelina A. Dziedzic, Jakub S. Gasior, Agnieszka Tuzimek, Waclaw Kochman
Summary: Women with coronary artery disease (CAD) are often misdiagnosed and undertreated. This study suggests a potential connection between acute coronary syndrome (ACS) and inflammation in women, and explores the relationship between inflammatory markers and traditional CAD risk factors. The findings indicate that these inflammatory markers may serve as new risk factors for CAD in elderly women.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Zsolt Bagyura, Loretta Kiss, Arpad Lux, Csaba Csobay-Novak, Adam L. Jermendy, Livia Polgar, Adam G. Tabak, Pal Soos, Zsolt Szelid, Bela Merkely, Laszlo Kohidai, Eva Pallinger
Summary: Several inflammatory biomarkers are associated with an increased risk of cardiovascular disease. Neutrophil-to-lymphocyte ratio (NLR) and visceral adiposity index (VAI) are markers of subclinical inflammation and reflect the function and extent of adipose tissue. This study aimed to examine the association between NLR and coronary artery calcium score (CACS) in asymptomatic patients across different VAI tertiles.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, General & Internal
Jianlong Sheng, Nina Liu, Fei He, Cheng Cheng, Shichun Shen, Yuting Sun
Summary: This study aimed to observe the changes in NLR and PLR before and after PCI in ACS patients, and found that patients had increased neutrophil proportion and NLR after PCI. NLR at 24h post-PCI was a better predictor of postoperative MACE incidence.
Article
Oncology
Qiang Hu, Weipu Mao, Tiange Wu, Zhipeng Xu, Junjie Yu, Can Wang, Saisai Chen, Shuqiu Chen, Bin Xu, Yueshuang Xu, Ming Chen
Summary: In RCC patients undergoing laparoscopic partial or radical nephrectomy, NLR and PLR were identified as biomarkers of systemic inflammation associated with increased risk of sarcopenia. The best cutoff points for predicting sarcopenia risk were NLR >2.88 and PLR >135.63, with higher levels indicating a greater risk. Adjusting for various variables, patients with NLR >2.88 and PLR >135.63 had significantly higher risks of developing sarcopenia compared to those with lower NLR or PLR levels.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Murat Sahin, Ayten Oguz, Dilek Tuzun, Okay Isiktas, Songul Isiktas, Cansu ulgen, Hatice Sahin, Kamile Gul
Summary: This study aimed to investigate whether the neutrophil-lymphocyte ratio (NLR), an indicator of systemic inflammation, could predict gestational diabetes mellitus (GDM). The results showed a significant increase in NLR in the 1st and 3rd trimesters in the GDM group, supporting the presence of systemic inflammation in early pregnancy and throughout pregnancy. The study also found a positive correlation between NLR and fasting plasma glucose and body mass index in both trimesters. The first trimester NLR was found to independently predict the development of GDM.
Article
Immunology
Qian Song, Song-Xiao Xu, Jun-Zhou Wu, Lin Ling, Sheng Wang, Xin-Hua Shu, Dan-Ni Ying, Wang-Wei Pei, Yu-Chen Wu, Su-Fang Sun, Yi-Ning Zhang, Si-Hang Zhou, Zhu-Yan Shao
Summary: This study analyzed data from 991 ovarian cancer patients and found that the lymphocyte to monocyte ratio (LMR) and platelet to neutrophil ratio (PNR) were independent prognostic indicators of ovarian cancer. In contrast, the platelet to lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) had limited prognostic value. In conclusion, LMR and PNR are superior prognostic indicators in ovarian cancer.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Immunology
Omer Okuyan, Yusuf Elgormus, Ugurcan Sayili, Seyma Dumur, Ozlem Erkan Isik, Hafize Uzun
Summary: This study evaluated the impact of the RV vaccine on the natural course of RV infections. The results showed that children who received the RV vaccine had lower rates of fever and hospitalization for acute gastroenteritis (AGE), and breastfeeding was also associated with a lower risk of infection. The neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and systemic immune inflammatory index (SII) were significantly higher in the RV-unvaccinated group.
Article
Multidisciplinary Sciences
Aysun Firat, Aysegul Ercan, Cengiz Mordeniz, Fatma Ferda Verit Atmaca
Summary: This study aimed to investigate whether the pretreatment hemogram parameters and their ratios can predict the endometrial transformation in patients with abnormal uterine bleeding. The study found that age, postmenopausal state, obesity, diabetes, and increased estrogen exposure were risk factors for endometrial atypia and carcinoma. Hemoglobin and hematocrit levels were significantly higher in early and advanced endometrial cancer groups, while platelet value was significantly higher in atypia and carcinoma groups.
Review
Immunology
Tracy Bhikram, Paul Sandor
Summary: The review found that NLR is elevated in certain adult psychiatric disorders like schizophrenia, major depressive disorder, and bipolar disorder, but the associations with symptom severity and clinical parameters are not entirely clear. Results in youth populations are similar to those in adults, indicating a need for further research to better understand the relationship between NLR and specific psychiatric disorders. Future work is required to determine the neuroinflammatory mechanisms underlying these disorders.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Article
Cardiac & Cardiovascular Systems
Gang-Qiong Liu, Wen-Jing Zhang, Jia-Hong Shangguan, Xiao-Dan Zhu, Wei Wang, Qian-Qian Guo, Jian-Chao Zhang, Kai Wang, Zhi-Yu Liu, Feng-Hua Song, Lei Fan, Ying-Ying Zheng, Jin-Ying Zhang
Summary: The study aimed to investigate the prognostic role of derived neutrophil-to-lymphocyte ratio (dNLR) in patients with coronary heart disease (CHD) after PCI. Results showed that dNLR is an independent and novel predictor of mortality in CHD patients after PCI, with higher dNLR associated with increased risk of mortality during long-term follow-up.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Health Care Sciences & Services
Guang-yun Cao, Jian-Chao Li, Wen-Jing Wang, Hai-Bo Wu
Summary: This study investigated the relationship between the neutrophil to lymphocyte ratio (NLR), the platelet to lymphocyte ratio (PLR), and cardiac syndrome X (CSX). The results showed that both NLR and PLR were significantly elevated in patients with CSX and had a certain predictive value for the occurrence of CSX, making them potential effective biomarkers for CSX.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2022)
Article
Medicine, Research & Experimental
Necati Uzun, Mehmet Akif Akinci
Summary: This study found that levels of white blood cells and neutrophils were significantly higher in children and adolescents with anxiety disorders compared to the control group. In addition, ratios such as neutrophil/lymphocyte, monocyte/lymphocyte, and platelet/lymphocyte were also significantly higher in the anxiety disorder group. Other hematological markers did not show significant differences between the study groups, except for RDW-CV which was higher in the AD-NOS group compared to GAD. These results suggest an association between inflammation and anxiety disorders, indicating that hematological parameters could potentially serve as markers for monitoring patients with anxiety disorders.
MEDICAL HYPOTHESES
(2021)
Article
Rheumatology
Umit Inci, Abdulkadir Yildiz, Ibrahim Batmaz, Ebru Tekbas
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2017)
Article
Medical Laboratory Technology
Ahmet Korkmaz, Abdulkadir Yildiz, Pinar Turker Duyuler, Serkan Duyuler, Samet Yilmaz, Funda Basyigit, Ozgul Ucar Elalmis, Umit Guray, Mehmet Ileri
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2018)
Editorial Material
Cardiac & Cardiovascular Systems
Serkan Duyuler, Pinar Turker Duyuler
ANATOLIAN JOURNAL OF CARDIOLOGY
(2017)
Article
Medicine, Research & Experimental
Serkan Duyuler
MEDICAL SCIENCE MONITOR
(2019)
Letter
Peripheral Vascular Disease
Serkan Duyuler, Kerem Ozbek, Kevser Gulcihan Balci, Ozlem Ozcan Celebi, Pinar Turker Duyuler
Article
Cardiac & Cardiovascular Systems
Pinar Turker Duyuler, Serkan Duyuler, Bekir Demirtas, Velihan Cayhan
Summary: This study found that increased thickness of epicardial and pericardial adipose tissue is associated with the severity of COVID-19 infection, as indicated by the need for ICU admission. These adipose tissue thickness measurements can serve as independent predictors of ICU admission.
Letter
Endocrinology & Metabolism
Serkan Duyuler, Pinar Turker Duyuler
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Article
Pharmacology & Pharmacy
P. Turker Duyuler, S. Duyuler, B. Demirtas, H. Cicekcioglu, V Cayhan
Summary: This study aimed to evaluate the association between electrocardiographic P wave indices and the severity of COVID-19 infection indicated as intensive care unit (ICU) admission. The results showed that P wave dispersion (Pdis) and P wave peak time (PWPT) were associated with ICU admission in newly diagnosed COVID-19 patients.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Mustafa Oylumlu, Muhammed Oylumlu, Bayram Arslan, Nihat Polat, Mehmet Ozbek, Muhammed Demir, Abdulkadir Yildiz, Nizamettin Toprak
POSTEPY W KARDIOLOGII INTERWENCYJNEJ
(2020)
Article
Cardiac & Cardiovascular Systems
Ahmet Korkmaz, Abdulkadir Yildiz, Harun Kundi, Funda Basyigit, Havva Tugba Gursoy, Ozgul Ucar Elalmis, Abdurrahman Akyuz, Mehmet Ileri, Umit Guray
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
(2018)
Article
Cardiac & Cardiovascular Systems
Pinar Turker Duyuler, Serkan Duyuler, Murat Gok, Harun Kundi, Canan Topcuoglu, Umit Guray
CORONARY ARTERY DISEASE
(2018)
Article
Peripheral Vascular Disease
Pinar Turker Duyuler, Serkan Duyuler, Mevlut Demir, Ozgul Ucar Elalmis, Umit Guray, Mehmet Ileri
BLOOD PRESSURE MONITORING
(2017)
Meeting Abstract
Cardiac & Cardiovascular Systems
P. Turker Duyuler, S. Duyuler, M. Gok, H. Kundi, C. Topcuoglu, U. Guray
EUROPEAN HEART JOURNAL
(2017)
Review
Pharmacology & Pharmacy
P. T. Duyuler, S. Duyuler, M. Demir
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2017)
