Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity

Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore

(2015) Ziqing Qian et al.   CHEMICAL COMMUNICATIONS

Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery

(2014) Ziqing Qian et al.   BIOCHEMISTRY

Amphiphilic Bicyclic Peptides as Cellular Delivery Agents

(2014) Donghoon Oh et al.   ChemMedChem

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

(2014) Loren D. Walensky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cell-Permeable Bicyclic Peptide Inhibitors against Intracellular Proteins

(2014) Wenlong Lian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses

(2013) Jeanine F. Amacher et al.   STRUCTURE

Efficient Delivery of Cyclic Peptides into Mammalian Cells with Short Sequence Motifs

(2012) Ziqing Qian et al.   ACS Chemical Biology

Hybrid Organic-Inorganic Inhibitors of a PDZ Interaction that Regulates the Endocytic Fate of CFTR

(2012) Rituparna Kundu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45

(2012) S. M. Stanford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational Design of a PDZ Domain Peptide Inhibitor that Rescues CFTR Activity

(2012) Kyle E. Roberts et al.   PLoS Computational Biology

CyLoP-1: A Novel Cysteine-Rich Cell-Penetrating Peptide for Cytosolic Delivery of Cargoes

(2011) Deepti Jha et al.   BIOCONJUGATE CHEMISTRY

Identification and Characterization of a New Family of Cell-penetrating Peptides

(2011) Laura Cascales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

(2011) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Stabilizing Influence: CAL PDZ Inhibition Extends the Half-Life of ΔF508-CFTR

(2010) Patrick R. Cushing et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PDZ domains and their binding partners: structure, specificity, and modification

(2010) Ho-Jin Lee et al.   Cell Communication and Signaling

Serum Stabilities of Short Tryptophan- and Arginine-Rich Antimicrobial Peptide Analogs

(2010) Leonard T. Nguyen et al.   PLoS One