Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett’s oesophagus

Curcumin Promotes Apoptosis, Increases Chemosensitivity, and Inhibits Nuclear Factor κB in Esophageal Adenocarcinoma

(2014) Wibisono Hartojo et al.   Translational Oncology

Curcumin induces apoptosis-independent death in oesophageal cancer cells

(2009) G O'Sullivan-Coyne et al.   BRITISH JOURNAL OF CANCER

Unlike Esophageal Squamous Cells, Barrett's Epithelial Cells Resist Apoptosis by Activating the Nuclear Factor- B Pathway

(2009) K. Hormi-Carver et al.   CANCER RESEARCH

Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-κB

(2008) Parvaneh Rafiee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells

(2008) Simone Reuter et al.   BIOCHEMICAL PHARMACOLOGY

Curcumin Sensitizes Human Colorectal Cancer Xenografts in Nude Mice to  -Radiation by Targeting Nuclear Factor- B-Regulated Gene Products

(2008) A. B. Kunnumakkara et al.   CLINICAL CANCER RESEARCH

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH

The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF- B activation in oesophageal cells, with a mechanism of action involving ROS

(2008) G. J. S. Jenkins et al.   MUTAGENESIS