Loss and Dysregulation of Th17 Cells during HIV Infection

The Myeloid Differentiation Factor 88 (MyD88) Is Required for CD4+ T Cell Effector Function in a Murine Model of Inflammatory Bowel Disease

(2014) M. Fukata et al.   JOURNAL OF IMMUNOLOGY

Altered Balance Between IL-17A– and IL-17F–Producing Th17 Cells in HIV-Infected Patients

(2013) Mohammad Salem et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

CD3+CD8+CD161high Tc17 cells are depleted in HIV-infection

(2012) Julie Christine Gaardbo et al.   AIDS

Paucity of IL-21-producing CD4+ T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques

(2012) L. Micci et al.   BLOOD

Incomplete Immune Recovery in HIV Infection: Mechanisms, Relevance for Clinical Care, and Possible Solutions

(2012) Julie C. Gaardbo et al.   Clinical & Developmental Immunology

IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis

(2012) Magdalena Huber et al.   JOURNAL OF CLINICAL INVESTIGATION

Tc17 CD8+ T Cells Potentiate Th1-Mediated Autoimmune Diabetes in a Mouse Model

(2012) A. Saxena et al.   JOURNAL OF IMMUNOLOGY

Human Th17 Cells Express High Levels of Enzymatically Active Dipeptidylpeptidase IV (CD26)

(2012) B. Bengsch et al.   JOURNAL OF IMMUNOLOGY

microRNA-301a regulation of a T-helper 17 immune response controls autoimmune demyelination

(2012) M. P. Mycko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the human T helper 17 cell phenotype

(2012) Francesco Annunziato et al.   TRENDS IN IMMUNOLOGY

Microbial translocation, immune activation, and HIV disease

(2012) Nichole R. Klatt et al.   TRENDS IN MICROBIOLOGY

A Randomized Case–Control Study of Dynamic Changes in Peripheral Blood Th17/Treg Cell Balance and Interleukin-17 Levels in Highly Active Antiretroviral-Treated HIV Type 1/AIDS Patients

(2011) Yan He et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Gut inflammation and indoleamine deoxygenase inhibit IL-17 production and promote cytotoxic potential in NKp44+ mucosal NK cells during SIV infection

(2011) R. K. Reeves et al.   BLOOD

HIV interferes with SOCS-1 and -3 expression levels driving immune activation

(2011) Regina C. Miller et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Low Level of Regulatory T Cells and Maintenance of Balance Between Regulatory T Cells and TH17 Cells in HIV-1–Infected Elite Controllers

(2011) Lea Brandt et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

(2011) Maud Mavigner et al.   JOURNAL OF CLINICAL INVESTIGATION

Upregulation of IL-21 Receptor on B Cells and IL-21 Secretion Distinguishes Novel 2009 H1N1 Vaccine Responders from Nonresponders among HIV-Infected Persons on Combination Antiretroviral Therapy

(2011) S. Pallikkuth et al.   JOURNAL OF IMMUNOLOGY

CD4+ T Cells, Including Th17 and Cycling Subsets, Are Intact in the Gut Mucosa of HIV-1-Infected Long-Term Nonprogressors

(2011) E. J. Ciccone et al.   JOURNAL OF VIROLOGY

Effect of Probiotic Bacteria on Microbial Host Defense, Growth, and Immune Function in Human Immunodeficiency Virus Type-1 Infection

(2011) Susanna Cunningham-Rundles et al.   Nutrients

HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells

(2010) Andrew Prendergast et al.   AIDS

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

(2010) Kiyoshi Hirahara et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC

(2010) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Loss of IL-17-Producing CD8 T Cells during Late Chronic Stage of Pathogenic Simian Immunodeficiency Virus Infection

(2010) P. Nigam et al.   JOURNAL OF IMMUNOLOGY

Suppressor of Cytokine Signaling 3 Inhibits Antiviral IFN-  Signaling To Enhance HIV-1 Replication in Macrophages

(2010) L. N. Akhtar et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection

(2010) Aimee El Hed et al.   JOURNAL OF INFECTIOUS DISEASES

Comprehensive Analysis of Frequency and Phenotype of T Regulatory Cells in HIV Infection: CD39 Expression of FoxP3+ T Regulatory Cells Correlates with Progressive Disease

(2010) J. Schulze zur Wiesch et al.   JOURNAL OF VIROLOGY

The Intracellular Delivery of a Recombinant Peptide Derived from the Acidic Domain of PIAS3 Inhibits STAT3 Transactivation and Induces Tumor Cell Death

(2010) C. Borghouts et al.   MOLECULAR CANCER RESEARCH

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease

(2010) D. Favre et al.   Science Translational Medicine

Development, regulation and functional capacities of Th17 cells

(2010) Keiji Hirota et al.   Seminars in Immunopathology

The enigma of the role of Protein inhibitor of Activated STAT3 (PIAS3) in the immune response

(2010) Zohar Yagil et al.   TRENDS IN IMMUNOLOGY

IL-21 augments natural killer effector functions in chronically HIV-infected individuals

(2009) Natasa Strbo et al.   AIDS

Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection

(2009) Lishomwa C Ndhlovu et al.   AIDS

Regulation and Function of Proinflammatory TH17 Cells

(2009) Gustavo J. Martinez et al.   Annals of the New York Academy of Sciences

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans

(2009) Frank L. van de Veerdonk et al.   Cell Host & Microbe

Essential and synergistic roles of IL1 and IL6 in human Th17 differentiation directed by TLR ligand-activated dendritic cells

(2009) Risa K. Benwell et al.   CLINICAL IMMUNOLOGY

Regulation of TH17 cells in the mucosal surfaces

(2009) Daniel Mucida et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infection

(2009) Kyung-Ah Kim et al.   JOURNAL OF HEPATOLOGY

Cutting Edge: In Vitro Generated Th17 Cells Maintain Their Cytokine Expression Program in Normal but Not Lymphopenic Hosts

(2009) R. Nurieva et al.   JOURNAL OF IMMUNOLOGY

Dynamics and Consequences of IL-21 Production in HIV-Infected Individuals: A Longitudinal and Cross-Sectional Study

(2009) Alexandre Iannello et al.   JOURNAL OF IMMUNOLOGY

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

(2009) A. Gosselin et al.   JOURNAL OF IMMUNOLOGY

TGF-  Promotes Th17 Cell Development through Inhibition of SOCS3

(2009) H. Qin et al.   JOURNAL OF IMMUNOLOGY

CD4 T cell subsets in the mucosa are CD28+Ki-67−HLA-DR−CD69+but show differential infection based on α4β7 receptor expression during acute SIV infection

(2009) M. Kader et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Anti-retroviral therapy fails to restore the severe Th-17: Tc-17 imbalance observed in peripheral blood during simian immunodeficiency virus infection

(2009) M. Kader et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Signal transduction and Th17 cell differentiation

(2009) John J. O'Shea et al.   MICROBES AND INFECTION

Properties and origin of human Th17 cells

(2009) Sergio Romagnani et al.   MOLECULAR IMMUNOLOGY

α4+β7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection

(2009) M Kader et al.   Mucosal Immunology

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

(2009) David Favre et al.   PLoS Pathogens

CCAAT/Enhancer Binding Protein β Is a Major Mediator of Inflammation and Viral Replication in the Gastrointestinal Tract of Simian Immunodeficiency Virus-Infected Rhesus Macaques

(2008) Mahesh Mohan et al.   AMERICAN JOURNAL OF PATHOLOGY

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Cytokines secreted in response to Toll-like receptor ligand stimulation modulate differentiation of human Th17 cells

(2008) Michael G. Kattah et al.   ARTHRITIS AND RHEUMATISM

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Regulatory T cells in human immunodeficiency virus-infected patients are elevated and independent of immunological and virological status, as well as initiation of highly active anti-retroviral therapy

(2008) J. C. Gaardbo et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Increased levels of regulatory T cells (Tregs) in human immunodeficiency virus-infected patients after 5 years of highly active anti-retroviral therapy may be due to increased thymic production of naive Tregs

(2008) L. Kolte et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

(2008) T Kobayashi et al.   GUT

Keeping Autoimmunity in Check: How to Control a Th17 Cell Controller

(2008) Roza I. Nurieva et al.   IMMUNITY

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells

(2008) Franca Gerosa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

(2008) Michelle A. Lowes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Antiretroviral Therapy prior to Acute Viral Replication Preserves CD4 T Cells in the Periphery but Not in Rectal Mucosa during Acute Simian Immunodeficiency Virus Infection

(2008) M. Kader et al.   JOURNAL OF VIROLOGY

Virus-Specific Interleukin-17-Producing CD4+ T Cells Are Detectable in Early Human Immunodeficiency Virus Type 1 Infection

(2008) F. Y. Yue et al.   JOURNAL OF VIROLOGY

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

(2008) V Cecchinato et al.   Mucosal Immunology

Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

(2008) M Macal et al.   Mucosal Immunology

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells

(2008) T. Korn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreased Levels of Circulating IL-21 in HIV-Infected AIDS Patients: Correlation with CD4+ T-Cell Counts

(2008) Alexandre Iannello et al.   VIRAL IMMUNOLOGY

Th17 and Allergy

(2008) Keisuke Oboki et al.   ALLERGOLOGY INTERNATIONAL