The Role of IL-33 in Rheumatic Diseases

IL-33 Induces Nuocytes and Modulates Liver Injury in Viral Hepatitis

(2013) Y. Liang et al.   JOURNAL OF IMMUNOLOGY

Serum levels of IL-33 and its receptor ST2 are elevated in patients with ankylosing spondylitis

(2013) G‐X Li et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Dermatomiosite e polimiosite: da imunopatologia à imunoterapia (imunobiológicos)

(2013) Samuel Katsuyuki Shinjo et al.   Revista Brasileira De Reumatologia

Increased serum IL-33 levels may indicate vascular involvement in systemic sclerosis

(2012) Sarah Terras et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-33 is overexpressed in the inflamed arteries of patients with giant cell arteritis

(2012) Francesco Ciccia et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-33 Is hepatoprotective during liver ischemia/reperfusion in mice

(2012) Nozomu Sakai et al.   HEPATOLOGY

Blockade of IL-33 ameliorates Con A-induced hepatic injury by reducing NKT cell activation and IFN-γ production in mice

(2012) Jie Chen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

(2012) E. Lefrancais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased circulating levels of interleukin 33 in systemic sclerosis correlate with early disease stage and microvascular involvement

(2011) M. Manetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin-21 modulates Th1 and Th17 responses in giant cell arteritis

(2011) Benjamin Terrier et al.   ARTHRITIS AND RHEUMATISM

Serum levels of IL-33 is increased in patients with ankylosing spondylitis

(2011) Guo-Wei Han et al.   CLINICAL RHEUMATOLOGY

IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils

(2011) Ho Jeong Na et al.   CYTOKINE

Measurement of Interleukin-33 (IL-33) and IL-33 Receptors (sST2 and ST2L) in Patients with Rheumatoid Arthritis

(2011) Yeon-Sik Hong et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Involvement of IL-33 in the pathogenesis of rheumatoid arthritis: the effect of etanercept on the serum levels of IL-33

(2011) Yasunori Kageyama et al.   Modern Rheumatology

IL-33 Induces IL-9 Production in Human CD4+ T Cells and Basophils

(2011) Lars Blom et al.   PLoS One

Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible association with persistent IL-1β signaling and a poor clinical response

(2011) Yasushi Matsuyama et al.   RHEUMATOLOGY INTERNATIONAL

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

(2010) W. A. Verri et al.   ANNALS OF THE RHEUMATIC DISEASES

Th17 and Th1 T-Cell Responses in Giant Cell Arteritis

(2010) Jiusheng Deng et al.   CIRCULATION

Association of increased serum IL-33 levels with clinical and laboratory characteristics of systemic lupus erythematosus in Chinese population

(2010) Zaixing Yang et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Expression and regulation of interleukin-33 in human monocytes

(2010) Christopher J. Nile et al.   IMMUNOLOGY

Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

(2010) Luca Pastorelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mean platelet volume in patients with rheumatoid arthritis: the effect of anti-TNF-alpha therapy

(2010) Armen Yuri Gasparyan et al.   RHEUMATOLOGY INTERNATIONAL

Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis

(2009) Gaby Palmer et al.   ARTHRITIS AND RHEUMATISM

IL-33, a recently identified interleukin-1 gene family member, is expressed in human adipocytes

(2009) I. Stuart Wood et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intracellular signaling mechanisms regulating the activation of human eosinophils by the novel Th2 cytokine IL-33: implications for allergic inflammation

(2009) Joyce YS Chow et al.   Cellular & Molecular Immunology

The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production

(2009) Elvire Bourgeois et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-33 is upregulated in colonocytes of ulcerative colitis

(2009) Jakob Benedict Seidelin et al.   IMMUNOLOGY LETTERS

Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage

(2009) Dominique Talabot-Ayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

(2009) D. Prefontaine et al.   JOURNAL OF IMMUNOLOGY

IL-33 Induces IL-13-Dependent Cutaneous Fibrosis

(2009) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

IL-33 Activates Unprimed Murine Basophils Directly In Vitro and Induces Their In Vivo Expansion Indirectly by Promoting Hematopoietic Growth Factor Production

(2009) E. Schneider et al.   JOURNAL OF IMMUNOLOGY

Increased Levels of Interleukin 33 in Sera and Synovial Fluid from Patients with Active Rheumatoid Arthritis

(2009) Y. MATSUYAMA et al.   JOURNAL OF RHEUMATOLOGY

The cytokine interleukin-33 mediates anaphylactic shock

(2009) P. N. Pushparaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus

(2009) M. Y. Mok et al.   RHEUMATOLOGY

Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors—Insight into Heterotrimeric IL-1 Signaling Complexes

(2009) Andreas Lingel et al.   STRUCTURE

Interleukin-33 – cytokine of dual function or novel alarmin?

(2009) Guttorm Haraldsen et al.   TRENDS IN IMMUNOLOGY

TRAF6 is a critical signal transducer in IL-33 signaling pathway

(2008) Megumi Funakoshi-Tago et al.   CELLULAR SIGNALLING

Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A–H2B acidic pocket

(2008) Lucie Roussel et al.   EMBO REPORTS

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

(2008) W. Brett Cherry et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?

(2008) Christine Moussion et al.   PLoS One

IL-33 exacerbates antigen-induced arthritis by activating mast cells

(2008) D. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA