Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1

Early Lymphoid Development and Microenvironmental Cues in B-cell Acute Lymphoblastic Leukemia

(2012) Jessica Purizaca et al.   ARCHIVES OF MEDICAL RESEARCH

Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia

(2012) P. Diamanti et al.   BLOOD

Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

(2012) C.-H. Pui et al.   BLOOD

Hematopoiesis: A Human Perspective

(2012) Sergei Doulatov et al.   Cell Stem Cell

Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations

(2012) Klaus Rehe et al.   EMBO Molecular Medicine

Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1

(2012) A R Soliera et al.   LEUKEMIA

The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior

(2011) Yan Liu et al.   CELL CYCLE

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

(2011) Lan-Lan Smith et al.   Cell Stem Cell

Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells

(2011) Julie R. Boiko et al.   CYTOKINE

Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells

(2011) Faiyaz Notta et al.   NATURE

Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation

(2011) Tarik Möröy et al.   SEMINARS IN IMMUNOLOGY

Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid development

(2010) H. Li et al.   BLOOD

Expression of the Transcriptional Repressor Gfi-1 Is Regulated by C/EBP  and Is Involved in Its Proliferation and Colony Formation-Inhibitory Effects in p210BCR/ABL-Expressing Cells

(2010) M. R. Lidonnici et al.   CANCER RESEARCH

Genetic variegation of clonal architecture and propagating cells in leukaemia

(2010) Kristina Anderson et al.   NATURE

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

(2010) Sergei Doulatov et al.   NATURE IMMUNOLOGY

Hematopoietic stem cell: self-renewal versus differentiation

(2010) Jun Seita et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Malignant stem cells in childhood ALL: the debate continues!

(2009) O. Heidenreich et al.   BLOOD

Expression of CD133 on leukemia-initiating cells in childhood ALL

(2009) C. V. Cox et al.   BLOOD

Individual and combined effects of mesenchymal stromal cells and recombinant stimulatory cytokines on the in vitro growth of primitive hematopoietic cells from human umbilical cord blood

(2009) Patricia Flores-Guzmán et al.   CYTOTHERAPY

Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection

(2008) R. S. Welner et al.   BLOOD

Stem cell concepts renew cancer research

(2008) J. E. Dick   BLOOD

In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties

(2008) Christoph le Viseur et al.   CANCER CELL

Defective in vitro growth of primitive hematopoietic cells from pediatric patients with acute myeloid leukemia

(2008) Elisa Dorantes-Acosta et al.   PEDIATRIC BLOOD & CANCER

Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia

(2008) D. Hong et al.   SCIENCE

The HOXB4 Homeoprotein Differentially Promotes Ex Vivo Expansion of Early Human Lymphoid Progenitors

(2007) Rima Haddad et al.   STEM CELLS