Role of Pore-Forming Toxins in Neonatal Sepsis

Recent Developments and Current Issues in the Epidemiology, Diagnosis, and Management of Bacterial and Fungal Neonatal Sepsis

(2013) Barbara Stoll et al.   AMERICAN JOURNAL OF PERINATOLOGY

Role for caspase-2 during pore-forming toxin-mediated apoptosis

(2012) Gergely Imre et al.   CELL CYCLE

The UPEC Pore-Forming Toxin α-Hemolysin Triggers Proteolysis of Host Proteins to Disrupt Cell Adhesion, Inflammatory, and Survival Pathways

(2012) Bijaya K. Dhakal et al.   Cell Host & Microbe

Pathogenic Pore-Forming Proteins: Function and Host Response

(2012) Mirko Bischofberger et al.   Cell Host & Microbe

Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner

(2012) Magali Perret et al.   CELLULAR MICROBIOLOGY

The biofilm in bacterial vaginosis

(2012) Hans Verstraelen et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

(2012) Gergely Imre et al.   EMBO JOURNAL

The RTX pore-forming toxin α-hemolysin of uropathogenicEscherichia coli: progress and perspectives

(2012) Travis J Wiles et al.   Future Microbiology

Development of a Single-Gene, Signature-Tag-Based Approach in Combination with Alanine Mutagenesis To Identify Listeriolysin O Residues Critical for theIn VivoSurvival of Listeria monocytogenes

(2012) Jody A. Melton-Witt et al.   INFECTION AND IMMUNITY

Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome

(2012) Chahnaz Kebaier et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome

(2012) Dirk Holzinger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Clinical Escherichia coli isolates utilize alpha-hemolysin to inhibit in vitro epithelial cytokine production

(2012) David W. Hilbert et al.   MICROBES AND INFECTION

Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota

(2012) Janelle S Ayres et al.   NATURE MEDICINE

Long-term Outcomes of Group B Streptococcal Meningitis

(2012) R. Libster et al.   PEDIATRICS

Serotype-independent pneumococcal experimental vaccines that induce cellular as well as humoral immunity

(2012) R. Malley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Listeriolysin O: the Swiss army knife of Listeria

(2012) Mélanie Anne Hamon et al.   TRENDS IN MICROBIOLOGY

Listeriolysin O Suppresses Phospholipase C-Mediated Activation of the Microbicidal NADPH Oxidase to Promote Listeria monocytogenes Infection

(2011) Grace Y. Lam et al.   Cell Host & Microbe

Gram-positive bacterial superantigen outside-in signaling causes toxic shock syndrome

(2011) Amanda J. Brosnahan et al.   FEBS Journal

pH dependence of listeriolysin O aggregation and pore-forming ability

(2011) Andrej Bavdek et al.   FEBS Journal

K+Efflux Is Required for Histone H3 Dephosphorylation by Listeria monocytogenes Listeriolysin O and Other Pore-Forming Toxins

(2011) Mélanie Anne Hamon et al.   INFECTION AND IMMUNITY

Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo

(2011) Francis Alonzo III et al.   MOLECULAR MICROBIOLOGY

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

The Burden of Invasive Early-onset Neonatal Sepsis in the United States, 2005–2008

(2011) Emily J. Weston et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Haemolysis induced by α-toxin from Staphylococcus aureus requires P2X receptor activation

(2011) Marianne Skals et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Panton-Valentine Leukocidin Does Play a Role in the Early Stage of Staphylococcus aureus Skin Infections: A Rabbit Model

(2011) Urszula Lipinska et al.   PLoS One

Crystal structure of the octameric pore of staphylococcal  -hemolysin reveals the  -barrel pore formation mechanism by two components

(2011) K. Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Listeria monocytogenestransiently alters mitochondrial dynamics during infection

(2011) Fabrizia Stavru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome

(2011) A. L. Radtke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxin Pores Endocytosed During Plasma Membrane Repair Traffic into the Lumen of MVBs for Degradation

(2011) Matthias Corrotte et al.   TRAFFIC

Prevalence of Escherichia coli among samples collected from the genital tract in pregnant and nonpregnant women: relationship with virulence

(2010) Elisabet Guiral et al.   FEMS MICROBIOLOGY LETTERS

Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

(2010) Christina Tam et al.   JOURNAL OF CELL BIOLOGY

TLR 2 and CD14 Mediate Innate Immunity and Lung Inflammation to Staphylococcal Panton-Valentine Leukocidin In Vivo

(2010) A. Zivkovic et al.   JOURNAL OF IMMUNOLOGY

Listeria monocytogenesInduces T Cell Receptor Unresponsiveness through Pore‐Forming Toxin Listeriolysin O

(2010) Nelson O. Gekara et al.   JOURNAL OF INFECTIOUS DISEASES

Bacterial Pore-Forming Cytolysins Induce Neuronal Damage in a Rat Model of Neonatal Meningitis

(2010) Anja Reiß et al.   JOURNAL OF INFECTIOUS DISEASES

Global, regional, and national causes of child mortality in 2008: a systematic analysis

(2010) Robert E Black et al.   LANCET

The interaction between a non-pathogenic and a pathogenic strain synergistically enhances extra-intestinal virulence in Escherichia coli

(2010) J. Tourret et al.   MICROBIOLOGY-SGM

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus  -hemolysin-mediated cellular injury

(2010) G. A. Wilke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell death during sepsis: integration of disintegration in the inflammatory response to overwhelming infection

(2009) Fabiano Pinheiro da Silva et al.   APOPTOSIS

The Molecular Basis for Perforin Oligomerization and Transmembrane Pore Assembly

(2009) Katherine Baran et al.   IMMUNITY

Anti-Alpha-Hemolysin Monoclonal Antibodies Mediate Protection against Staphylococcus aureus Pneumonia

(2009) B. E. Ragle et al.   INFECTION AND IMMUNITY

Relevance of Fatty Acid Covalently Bound to Escherichia coli α-Hemolysin and Membrane Microdomains in the Oligomerization Process

(2009) Vanesa Herlax et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

(2009) Marcus Mueller et al.   NATURE

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

 -Hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis

(2009) M. Skals et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NOD2 contributes to cutaneous defense against Staphylococcus aureus through  -toxin-dependent innate immune activation

(2009) P. Hruz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of Zebrafish to Probe the Divergent Virulence Potentials and Toxin Requirements of Extraintestinal Pathogenic Escherichia coli

(2009) Travis J. Wiles et al.   PLoS Pathogens

Analysis of the Specificity of Panton-Valentine Leucocidin and Gamma-Hemolysin F Component Binding

(2008) F. Meyer et al.   INFECTION AND IMMUNITY

Hemolysin of Uropathogenic Escherichia coli Evokes Extensive Shedding of the Uroepithelium and Hemorrhage in Bladder Tissue within the First 24 Hours after Intraurethral Inoculation of Mice

(2008) Y. C. Smith et al.   INFECTION AND IMMUNITY

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

(2008) Vincent Idone et al.   JOURNAL OF CELL BIOLOGY

Signals Triggered by a Bacterial Pore-Forming Toxin Contribute to Toll-Like Receptor Redundancy in Gram-Positive Bacterial Recognition

(2008) Nelson O. Gekara et al.   JOURNAL OF INFECTIOUS DISEASES

GILT is a critical host factor for Listeria monocytogenes infection

(2008) Reshma Singh et al.   NATURE

Group B Streptococcal β-Hemolysin/Cytolysin Directly Impairs Cardiomyocyte Viability and Function

(2008) Mary E. Hensler et al.   PLoS One

Disparate proteins use similar architectures to damage membranes

(2008) Gregor Anderluh et al.   TRENDS IN BIOCHEMICAL SCIENCES

CAMP factor is not essential for systemic virulence of Group B Streptococcus

(2007) Mary E. Hensler et al.   MICROBIAL PATHOGENESIS