Interferon Lambda: A New Sword in Cancer Immunotherapy

An Important Role for Type III Interferon (IFN- /IL-28) in TLR-Induced Antiviral Activity

(2014) N. Ank et al.   JOURNAL OF IMMUNOLOGY

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

(2011) Christoph Thomas et al.   CELL

IL-28A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease

(2011) Ourania Koltsida et al.   EMBO Molecular Medicine

Interferon lambdas: the next cytokine storm

(2011) C. Kelly et al.   GUT

Variants génétiques du gèneIL28Bet élimination du virus de l’hépatite C

(2011) Dominique Labie et al.   M S-MEDECINE SCIENCES

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFN-α and IFN-λ differ in their antiproliferative effects and duration of JAK/STAT signaling activity

(2010) Stephen G. Maher et al.   CANCER BIOLOGY & THERAPY

Antitumor activity of Type I and Type III interferons in BNL hepatoma model

(2010) Walid Abushahba et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Resistance to transforming growth factor  -mediated tumor suppression in melanoma: are multiple mechanisms in place?

(2010) A. Lasfar et al.   CARCINOGENESIS

An IL28B Polymorphism Determines Treatment Response of Hepatitis C Virus Genotype 2 or 3 Patients Who Do Not Achieve a Rapid Virologic Response

(2010) Alessandra Mangia et al.   GASTROENTEROLOGY

Replicated Association Between an IL28B Gene Variant and a Sustained Response to Pegylated Interferon and Ribavirin

(2010) Jeanette J. McCarthy et al.   GASTROENTEROLOGY

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

Interferon lambda inhibits herpes simplex virus type I infection of human astrocytes and neurons

(2010) Jieliang Li et al.   GLIA

Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes

(2010) Marco Antonio Montes-Cano et al.   HEPATOLOGY

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

(2010) Andrew J. Muir et al.   HEPATOLOGY

Large‐Scale Candidate Gene Analysis of Spontaneous Clearance of Hepatitis C Virus

(2010) Timothy L. Mosbruger et al.   JOURNAL OF INFECTIOUS DISEASES

Interferon-Lambda: A New Addition to an Old Family

(2010) Raymond P. Donnelly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

(2010) M. Mordstein et al.   JOURNAL OF VIROLOGY

Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

(2010) N. A. Jewell et al.   JOURNAL OF VIROLOGY

Temporal and Spatial Resolution of Type I and III Interferon Responses In Vivo

(2010) J. E. Pulverer et al.   JOURNAL OF VIROLOGY

IFN- 1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells

(2009) J. Dai et al.   BLOOD

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

(2009) M. P. Morrow et al.   BLOOD

Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines

(2009) K Witte et al.   GENES AND IMMUNITY

Interferon-λs: the modulators of antivirus, antitumor, and immune responses

(2009) Mingcai Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Modulation of human plasmacytoid DC function by IFN-λ1 (IL-29)

(2009) Nicholas J. Megjugorac et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intranasal Administration of Alpha Interferon Reduces Seasonal Influenza A Virus Morbidity in Ferrets

(2009) D. Kugel et al.   JOURNAL OF VIROLOGY

Lambda Interferon Inhibits Human Immunodeficiency Virus Type 1 Infection of Macrophages

(2009) W. Hou et al.   JOURNAL OF VIROLOGY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Liver Transplantation for Hepatocellular Carcinoma

(2008) Vincenzo Mazzaferro et al.   ANNALS OF SURGICAL ONCOLOGY

Radiofrequency Ablation and Chemoembolization for Hepatocellular Carcinoma

(2008) Christos S. Georgiades et al.   CANCER JOURNAL

Regulation of apoptosis by type III interferons

(2008) W. Li et al.   CELL PROLIFERATION

Type III IFN-λ mRNA expression in sputum of adult and school-aged asthmatics

(2008) Dominique M. A. Bullens et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Human interferon-λ3 is a potent member of the type III interferon family

(2008) C Dellgren et al.   GENES AND IMMUNITY

Interferon-λ1 (interleukin-29) preferentially down-regulates interleukin-13 over other T helper type 2 cytokine responsesin vitro

(2008) Shekar Srinivas et al.   IMMUNOLOGY

Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes

(2008) Kerstin Wolk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis

(2008) Vincenzo Mazzaferro et al.   LANCET ONCOLOGY

A role for IFN-λ1 in multiple myeloma B cell growth

(2008) A J Novak et al.   LEUKEMIA

Combination Therapy with S-1 and Pegylated Interferon Alpha for Advanced Hepatocellular Carcinoma

(2008) Kazuomi Ueshima et al.   ONCOLOGY

Transforming growth factor-β in cutaneous melanoma

(2008) Delphine Javelaud et al.   Pigment Cell & Melanoma Research

Therapeutic Strategy of Advanced Hepatocellular Carcinoma by Using Combined Intra-Arterial Chemotherapy

(2008) Hidenari Nagai et al.   Recent Patents on Anti-Cancer Drug Discovery

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens