Innate Immune Sensors and Gastrointestinal Bacterial Infections

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Interferon-gamma secretion is induced in IL-12 stimulated human NK cells by recognition of Helicobacter pylori or TLR2 ligands

(2010) Åsa Lindgren et al.   Innate Immunity

Inflammatory bowel disease: Established and evolving considerations on its etiopathogenesis and therapy

(2010) Anja SCHIRBEL et al.   Journal of Digestive Diseases

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of infection in the aetiology of inflammatory bowel disease

(2010) Richard Hansen et al.   JOURNAL OF GASTROENTEROLOGY

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

The Induction of Colitis and Ileitis in Mice Is Associated with Marked Increases in Intestinal Concentrations of Stimulants of TLRs 2, 4, and 5

(2010) Clett Erridge et al.   PLoS One

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System?

(2010) Y. K. Lee et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

A Genome-wide In Vitro Bacterial-Infection Screen Reveals Human Variation in the Host Response Associated with Inflammatory Disease

(2009) Dennis C. Ko et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The innate immune molecule, NOD1, regulates direct killing ofHelicobacter pyloriby antimicrobial peptides

(2009) Alexandra Grubman et al.   CELLULAR MICROBIOLOGY

Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells

(2009) Maria Kaparakis et al.   CELLULAR MICROBIOLOGY

The Role of the Gastrointestinal Microbiota in Colorectal Cancer

(2009) Ian Rowland   CURRENT PHARMACEUTICAL DESIGN

CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations

(2009) Georgina L. Hold et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Extracellular and Intracellular Pattern Recognition Receptors Cooperate in the Recognition of Helicobacter pylori

(2009) Roland Rad et al.   GASTROENTEROLOGY

Toll-like receptor 4 signalling through MyD88 is essential to controlSalmonella entericaserovar Typhimurium infection, but not for the initiation of bacterial clearance

(2009) Suzanne Talbot et al.   IMMUNOLOGY

Role of Nod1 in Mucosal Dendritic Cells during Salmonella Pathogenicity Island 1-Independent Salmonella enterica Serovar Typhimurium Infection

(2009) L. Le Bourhis et al.   INFECTION AND IMMUNITY

Increase in NF- B Binding Affinity of the Variant C Allele of the Toll-Like Receptor 9 -1237T/C Polymorphism Is Associated with Helicobacter pylori-Induced Gastric Disease

(2009) M. T. H. Ng et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 5-Dependent Regulation of Inflammation in Systemic Salmonella enterica Serovar Typhimurium Infection

(2009) B. Fournier et al.   INFECTION AND IMMUNITY

MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3

(2009) E. F. Kenny et al.   JOURNAL OF IMMUNOLOGY

The role of TLRs, NLRs and RLRs in mucosal innate immunity and homeostasis

(2009) E C Lavelle et al.   Mucosal Immunology

A Crohn's disease–associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1

(2009) Eiichiro Noguchi et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Activating immunity: lessons from the TLRs and NLRs

(2009) Tom P. Monie et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Function of Nod-like receptors in microbial recognition and host defense

(2008) Luigi Franchi et al.   IMMUNOLOGICAL REVIEWS

TLR4-induced IFN-γ production increases TLR2 sensitivity and drives Gram-negative sepsis in mice

(2008) Stephan Spiller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

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(2008) Steven Gribar et al.   MOLECULAR MEDICINE

Role of Toll-like receptors in gastrointestinal malignancies

(2008) M Fukata et al.   ONCOGENE

Polymorphisms in Toll-like receptor genes and risk of cancer

(2008) E M El-Omar et al.   ONCOGENE