Comparative Approach to Define Increased Regulatory T Cells in Different Cancer Subtypes by Combined Assessment of CD127 and FOXP3

Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13

(2011) Rachel F. Gabitass et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia

(2010) Lukas Weiss et al.   CANCER

Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre- versus post-vaccination

(2010) Matteo Vergati et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Increased regulatory T-cell frequencies in patients with advanced melanoma correlate with a generally impaired T-cell responsiveness and are restored after dendritic cell-based vaccination

(2010) Anita Correll et al.   EXPERIMENTAL DERMATOLOGY

Naturally occurring CD4+ CD25+ FOXP3+ T-regulatory cells are increased in chronic myeloid leukemia patients not in complete cytogenetic remission and can be immunosuppressive

(2010) Jose M. Rojas et al.   EXPERIMENTAL HEMATOLOGY

Plasticity of Treg cells: Is reprogramming of Treg cells possible in the presence of FOXP3?

(2010) Marc Beyer et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CD4+CD25+CD127low/− regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression

(2009) Li-Song Shen et al.   CLINICAL IMMUNOLOGY

Regulatory T Cells: Major Players in the Tumor Microenvironment

(2009) Marc Beyer et al.   CURRENT PHARMACEUTICAL DESIGN

Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation

(2009) Petra Hoffmann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Local and systemic induction of CD4+CD25+ regulatory T-cell population by non-Hodgkin lymphoma

(2008) S. Mittal et al.   BLOOD

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL