Journal
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Volume 135, Issue 7, Pages 1711-1712Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/jid.2014.544
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Early events during dengue virus (DENV) infection remain poorly understood. In this issue, Schaeffer and colleagues employ ex vivo human skin cells to investigate viral infection. They show that skin-resident immune cells are infected by DENV and that their infectability is increased in the inflammatory skin conditions (especially those in which IL-4 is released) that accompany the mosquito bites transmitting the virus.
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