Article
Endocrinology & Metabolism
Bingqi Ye, Qian Zhao, Jiahua Fan, Xiaomei Li, Chunfang Shan, Fen Liu, Ning Song, Jiajun Zhu, Min Xia, Yan Liu, Yining Yang
Summary: This study examined the prognostic value of baseline RBP4 and its derived multimarker score for major adverse cardiovascular events (MACEs) in patients with acute coronary syndrome (ACS). The results showed that the RBP4-derived multimarker score was significantly associated with the risk of MACEs and could be a useful tool for risk stratification and decision support in ACS patients.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Construction & Building Technology
Cassio K. Hui, Tess X. Luo, Wallace W. Lai, Ray K. Chang
Summary: This study proposes a method to synchronize GPR scans in areas with poor or no GNSS coverage, using a mobile mapping system (MMS) backpack guided by SLAM. It aims to improve the efficiency of GPR surveys in dense urban areas where good GNSS coverage is unavailable.
TUNNELLING AND UNDERGROUND SPACE TECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Zhenjun Yu, Yu Zhang, Yingying Cao, Manman Xu, Shaoli You, Yu Chen, Bing Zhu, Ming Kong, Fangjiao Song, Shaojie Xin, Zhongping Duan, Tao Han
Summary: The study aimed to establish and validate a new scoring system to predict short-term prognosis in patients with acute-on-chronic liver failure using baseline and dynamic data. The new model, based on clinical data, showed better prognostic ability than current scoring systems.
SCIENTIFIC REPORTS
(2021)
Article
Gastroenterology & Hepatology
Stig Borbjerg Laursen, Kathryn Oakland, Loren Laine, Vered Bieber, Riccardo Marmo, Eduardo Redondo-Cerezo, Harry R. Dalton, Jeffrey Ngu, Michael Schultz, Marco Soncini, Ian Gralnek, Vipul Jairath, Iain A. Murray, Adrian J. Stanley
Summary: The ABC score shows better performance in predicting mortality in UGIB and LGIB patients compared to existing scores, allowing for early identification and targeted management of high or low-risk patients.
Article
Medicine, General & Internal
Naofumi Sato, Ryoji Ogura, Yuji Iwanami, Ikuko Okuni, Satoru Ebihara
Summary: This study examined the effects of L-menthol olfactory stimulation on exertional dyspnea in patients with chronic breathlessness syndrome. The results showed that L-menthol olfactory stimulation can reduce dyspnea in these patients. Evaluation: 8/10.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Justas Simonavicius, Aurimas Mikalauskas, Kamil E. Cerlinskait, Etienne Gayat, Vytautas Juknevicius, Egle Paleviciute, Irina Alitoit-Marrote, Denis Kablucko, Loreta Bagdonaite, Mindaugas Balciunas, Dovile Vaiciuliene, Ieva Jonauskiene, Justina Motiejunaite, Kestutis Stasaitis, Audrys Kukulskis, Sarunas Damalakas, Toma Simbelyte, Neringa Taparauskaite, Gintare Pukanasiene, Aleksandras Laucevicius, Ausra Kavoliuniene, Alexandre Mebazaa, Jelena Celutkiene
Summary: This study evaluates the role of biologically active adrenomedullin in congestion assessment and risk stratification in acute dyspnea. Congestion was assessed using clinical and sonographic parameters, and 90-day mortality was chosen for outcome analysis.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Medicine, General & Internal
Michael Xiang, Ting Martin Ma, Ricky Savjani, Erqi L. Pollom, R. Jeffrey Karnes, Tristan Grogan, Jessica K. Wong, Giovanni Motterle, Jeffrey J. Tosoian, Bruce J. Trock, Eric A. Klein, Bradley J. Stish, Robert T. Dess, Daniel E. Spratt, Avinash Pilar, Chandana Reddy, Rebecca Levin-Epstein, Trude B. Wedde, Wolfgang A. Lilleby, Ryan Fiano, Gregory S. Merrick, Richard G. Stock, D. Jeffrey Demanes, Brian J. Moran, Hartwig Huland, Phuoc T. Tran, Santiago Martin, Rafael Martinez-Monge, Daniel J. Krauss, Eyad I. Abu-Isa, Ridwan Alam, Zeyad Schwen, Thomas M. Pisansky, C. Richard Choo, Daniel Y. Song, Stephen Greco, Curtiland Deville, Todd McNutt, Theodore L. DeWeese, Ashley E. Ross, Jay P. Ciezki, Paul C. Boutros, Nicholas G. Nickols, Prashant Bhat, David Shabsovich, Jesus E. Juarez, Natalie Chong, Patrick A. Kupelian, Matthew B. Rettig, Nicholas G. Zaorsky, Alejandro Berlin, Jonathan D. Tward, Brian J. Davis, Robert E. Reiter, Michael L. Steinberg, David Elashoff, Eric M. Horwitz, Rahul D. Tendulkar, Derya Tilki, Johannes Czernin, Andrei Gafita, Tahmineh Romero, Jeremie Calais, Amar U. Kishan
Summary: PSMA PET/CT can detect previously occult nonlocalized prostate cancer with important clinical implications. The upstaging probability on PSMA PET/CT is associated with long-term prognosis and shows superior risk discrimination compared with existing tools in high-risk patients.
Article
Emergency Medicine
Omide Taheri, Frederic Mauny, Patrick Ray, Marc Puyraveau, Alain-Eric Dubart, Camille Chenevier-Gobeaux, Marie-France Seronde, Alexandre Mebazaa, Berenger Martin, Jean-Baptiste Pretalli, Thibaut Desmettre, READ Study grp
Summary: This study aimed to evaluate the diagnostic accuracy of NT-proBNP, Hs-cTnI, ST2, galectin-3, and CD146 in diagnosing AHF in elderly patients with acute dyspnea. The results showed that NT-proBNP alone exhibited the best diagnostic accuracy, and the use of other biomarkers alone or in combination did not improve the accuracy.
EUROPEAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Endocrinology & Metabolism
Hong Pan, Shasha Lin
Summary: This study found that HALP score is associated with the risk of cardiovascular and all-cause mortality, but not cerebrovascular mortality.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Kazuki Ocho, Hideharu Hagiya, Kou Hasegawa, Kouji Fujita, Fumio Otsuka
Summary: This study analyzed data from COVID-19 patients in Japan to assess the utility of the 4C mortality score compared to conventional scorings. The results showed that the 4C mortality score is better than other scoring systems for estimating mortality and severity in COVID-19 Japanese patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Simon Butikofer, Mehtap Greutmann-Yantiri, Christoph Gubler, Cecilia Reiner, Hatem Alkadhi, Thomas Pfammatter, Gilbert Puippe, Bruno Santos Lopes, Mathias Possner, Francesca Bonassin, Lukas Meier, Daniela Babic, Christine Attenhofer Jost, Christoph Jungst, Beat Mullhaupt, Christine Bernsmeier, Markus Schwerzmann, Daniel Tobler, Daniela Lenggenhager, Ewerton Marques Maggio, Matthias Greutmann
Summary: The study aimed to assess the prevalence and predictors of advanced liver fibrosis in Fontan patients and the utility of liver stiffness measurement by ultrasound transient elastography. The results showed that advanced liver fibrosis was present in the majority of adult Fontan patients, and liver stiffness measurement was not associated with the degree of liver fibrosis. Younger age at completion of Fontan was associated with advanced liver fibrosis.
CANADIAN JOURNAL OF CARDIOLOGY
(2023)
Article
Immunology
Joshua Knight, Adam Hill, Vladyslav Melnyk, Luke Doney, Jonathan D'Cunha, Tanya Kenkre, Kathirvel Subramaniam, Kimberly Howard-Quijano
Summary: This study revealed that >15 minutes of intraoperative hypoxia was independently associated with postoperative acute kidney injury (AKI) after bilateral orthotopic lung transplant (BOLTx).
Article
Multidisciplinary Sciences
Anees Ur Rehman, Shahid Shah, Ghulam Abbas, Sabariah Noor Harun, Sadia Shakeel, Rabia Hussain, Mohamed Azmi Ahmad Hassali, Muhammad Fawad Rasool
Summary: This study aimed to investigate the impact of different factors on rapid deterioration of lung function in COPD patients, and found that smoking, disease severity, mMRC score, SGRQ-C score, 6MWT distance, exacerbation frequency, hospital admission days, Charlson comorbidity index, and emphysema were significant risk factors for FEV1 decline >= 60 ml in one year. Among these factors, a CCI score >= 3, abrupt decline in health status, exacerbation frequency >= 3, hospital admission days >= 8, and emphysema were reported as risk factors for rapid deterioration of lung function.
SCIENTIFIC REPORTS
(2021)
Article
Physiology
Devin B. Phillips, Matthew D. James, Conor D. O'Donnell, Sandra G. Vincent, Katherine A. Webb, Juan P. de-Torres, J. Alberto Neder, Denis E. O'Donnell
Summary: Low resting inspiratory capacity (IC) is closely associated with exertional dyspnea, exercise limitation, and poor survival in COPD. Meanwhile, maximal inspiratory pressure (MIP) has no significant impact on these variables. Resting IC is a stronger predictor of peak oxygen uptake (VO2peak) compared to MIP. Low resting IC remains independently associated with worse survival in COPD after accounting for airway obstruction, inspiratory muscle strength, and diffusing capacity.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Yoji Tamaki, Hiroyuki Iwano, Michito Murayama, Suguru Ishizaka, Ko Motoi, Hiroyuki Aoyagi, Kosuke Nakamura, Mana Goto, Yukino Suzuki, Shinobu Yokoyama, Hisao Nishino, Masahiro Nakabachi, Sanae Kaga, Kiwamu Kamiya, Toshiyuki Nagai, Toshihisa Anzai
Summary: This study evaluated the usefulness of the visually assessed time difference between the mitral valve and tricuspid valve opening (VMT) score in detecting acute heart failure (AHF) in dyspnea patients. The results showed that the VMT score had high diagnostic accuracy in diagnosing AHF. The combination of VMT score and lung ultrasonography (LUS) could provide a reliable strategy for non-cardiologists to diagnose AHF.
JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Anju Bhardwaj, Shafiq U. Rehman, Asim Mohammed, Aaron L. Baggish, Stephanie A. Moore, James L. Januzzi
AMERICAN HEART JOURNAL
(2010)
Article
Cardiac & Cardiovascular Systems
Anju Bhardwaj, Shafiq U. Rehman, Asim A. Mohammed, Hanna K. Gaggin, Linda Barajas, Justine Barajas, Stephanie A. Moore, Dorothy Sullivan, James L. Januzzi
AMERICAN HEART JOURNAL
(2012)
Article
Biotechnology & Applied Microbiology
Abelardo A. Martinez-Rumayor, Josue Vazquez, Shafiq U. Rehman, James L. Januzzi
Review
Cardiac & Cardiovascular Systems
Shafiq U. Rehman, James L. Januzzi
CARDIOLOGY IN REVIEW
(2008)
Article
Cardiac & Cardiovascular Systems
Rory B. Weiner, Aaron L. Baggish, Annabel Chen-Tournoux, Jane E. Marshall, Hanna K. Gaggin, Anju Bhardwaj, Asim A. Mohammed, Shafiq U. Rehman, Linda Barajas, Justine Barajas, Shawn A. Gregory, Stephanie A. Moore, Marc J. Semigran, James L. Januzzi
EUROPEAN JOURNAL OF HEART FAILURE
(2013)
Article
Cardiac & Cardiovascular Systems
Hanna K. Gaggin, Asim A. Mohammed, Anju Bhardwaj, Shafiq U. Rehman, Shawn A. Gregory, Rory B. Weiner, Aaron L. Baggish, Stephanie A. Moore, Marc J. Semigran, James L. Januzzi
JOURNAL OF CARDIAC FAILURE
(2012)
Article
Cardiac & Cardiovascular Systems
Shafiq U. Rehman, Thomas Mueller, James L. Januzzi
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2008)
Article
Cardiac & Cardiovascular Systems
James L. Januzzi, Shafiq U. Rehman, Asim A. Mohammed, Anju Bhardwaj, Linda Barajas, Justine Barajas, Han-Na Kim, Aaron L. Baggish, Rory B. Weiner, Annabel Chen-Tournoux, Jane E. Marshall, Stephanie A. Moore, William D. Carlson, Gregory D. Lewis, Jordan Shin, Dorothy Sullivan, Kimberly Parks, Thomas J. Wang, Shawn A. Gregory, Shanmugam Uthamalingam, Marc J. Semigran
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2011)
Article
Multidisciplinary Sciences
Jason C. Siegler, Shafiq Rehman, Geetha P. Bhumireddy, Raushan Abdula, Igor Klem, Sorin J. Brener, Leonard Lee, Christopher C. Dunbar, Barry Saul, Terrence J. Sacchi, John F. Heitner
Article
Cardiac & Cardiovascular Systems
Shafiq U. Rehman, James L. Januzzi
CURRENT CARDIOLOGY REVIEWS
(2008)
Article
Medical Laboratory Technology
Jiansheng Lin, Weihua Lin, Yiming Lin, Weilin Peng, Zhenzhu Zheng
Summary: This study retrospectively analyzed the cases of Chinese infants with NICCD and identified multiple genetic mutations. The study also found comorbidity of NICCD and other inborn errors of metabolism in some patients.
CLINICA CHIMICA ACTA
(2024)
Review
Medical Laboratory Technology
Lihua Guan, Wei Su, Jian Zhong, Ling Qiu
Summary: Multiple myeloma is characterized by excessive production of monoclonal immunoglobulins. Routine screening methods are insufficient for detecting low levels of M proteins, but advances in mass spectrometry enable reliable detection of low abundance serum biomarkers for minimal residual disease assessment in multiple myeloma.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Liya Zhu, Chao Zhu, Jialie Jin, Jinxin Wang, Xiaojing Zhao, Rongxi Yang
Summary: This study found an association between blood-based ITGB2 methylation and coronary heart disease (CHD), with hypomethylation of ITGB2 being a risk factor for CHD. Additionally, the combination of ITGB2 methylation and conventional CHD risk factors could efficiently discriminate CHD patients from controls.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
H. Al Habobe, E. B. Haverkort, K. Nazmi, A. P. Van Splunter, R. H. H. Pieters, F. J. Bikker
Summary: Saliva diagnostics have become popular due to their non-invasive nature and patient-friendly collection process. However, the choice of saliva collection method can affect the measured levels of various biomarkers.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Abdurrahman Coskun, Anna Carobene, Ozlem Demirelce, Michele Mussap, Federica Braga, Ebru Sezer, Aasne Karine Aarsand, Sverre Sandberg, Pilar Fernandez Calle, Jorge Diaz-Garzon, Metincan Erkaya, Cihan Coskun, Esila Nur Erol, Hunkar Dag, Bill Bartlett, Mustafa Serteser, Niels Jonker, Ibrahim Unsal
Summary: In this study, BV estimates for 22 AAs were provided based on a large sample size, and it was found that there are differences in CVI estimates between males and females for most AAs, which has implications for the clinical interpretation and use of AAs.
CLINICA CHIMICA ACTA
(2024)
Review
Medical Laboratory Technology
Valentinus Besin, Farizky Martriano Humardani, Trilis Yulianti, Matthew Justyn
Summary: The study of Parkinson's Disease in Asian populations has revealed the impact of genetic variants on multiple biological pathways and highlighted shared genetic susceptibility with other diseases. These findings emphasize the importance of personalized treatment based on individual genetic profiles.
CLINICA CHIMICA ACTA
(2024)
Review
Medical Laboratory Technology
Simona Ferraro, Sara Benedetti, Savina Mannarino, Santica Marcovina, Elia Mario Biganzoli, Gianvincenzo Zuccotti
Summary: Risk stratification for cardio-vascular disease should be implemented in childhood to promote early prevention strategies, as atherosclerotic lesions can be present even in very young individuals. Evaluating pediatric CV risk factors/clinical conditions and conducting lipid profile and genetic testing can help identify children at risk of future CV events and guide appropriate therapeutic options.
CLINICA CHIMICA ACTA
(2024)
Review
Medical Laboratory Technology
Ahmad Mobed, Bita Abdi, Sajjad Masoumi, Mohammad Mikaeili, Elham Shaterian, Hamed Shaterian, Esmat Sadat Kazemi, Mahdiye Shirafkan
Summary: Reproductive biomarkers play important regulatory roles in women. The discovery and quantification of these biomarkers are clinically significant. Various detection strategies, including nanotechnology-based methods, have been developed. This article provides an in-depth introduction to the latest advances in biosensor and nanosensor research for detecting and quantitatively identifying reproductive biomarkers.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Chengfang Tang, Fang Tang, Yanna Cai, Minyi Tan, Sichi Liu, Ting Xie, Xiang Jiang, Yonglan Huang
Summary: This study proposes an effective method for screening X-ALD and evaluates the performance of newborn screening for X-ALD in Guangzhou. The LC-MS/MS method can accurately identify X-ALD through analysis of C26:0-LPC.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Lan Liu, Jiamin Wang, Xijing Liu, Jing Wang, Lin Chen, Hongmei Zhu, Jingqun Mai, Ting Hu, Shanling Liu
Summary: The 16p11.2 deletion is a common genetic cause of neurodevelopmental disorders, with prenatal and postnatal presentations including vertebral malformations and language impairment. The majority of deletions are de novo and may be associated with MAPK3 and histidine-associated metabolism.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Sneha Venkatesalu, Shanmugapriya Dilliyappan, Avanthika Satish Kumar, Thirunavukkarasu Palaniyandi, Gomathy Baskar, Maddaly Ravi, Asha Sivaji
Summary: Microfluidics is a science and technology that deals with less sample-to-more precision in vitro analysis. It has wide applications in cancer theranostics, enabling precise diagnosis and personalized treatment.
CLINICA CHIMICA ACTA
(2024)
Review
Medical Laboratory Technology
Yuanqin Zhao, Wei Deng, Zhaoyue Wang, Yanxia Wang, Hongyu Zheng, Kun Zhou, Qian Xu, Le Bai, Huiting Liu, Zhong Ren, Zhisheng Jiang
Summary: The cardiovascular system and the central nervous system exhibit a coordinated developmental process during embryonic development. Congenital heart disease (CHD) is the most common congenital disorder, and neurodevelopmental disorders (NDD) are common complications in CHD patients. Both genetic and non-genetic factors contribute to the co-occurrence of CHD and NDD. Further research should focus on identifying common molecular mechanisms underlying this co-occurrence and promoting the research and treatment of developmental disorders related to the cardiovascular and central nervous systems.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Karol Gostomczyk, Ewelina Lukaszewska, Jedrzej Borowczak, Anita Bator, Marek Zdrenka, Magdalena Bodnar, Lukasz Szylberg
Summary: Flow cytometry improves the detection of epithelial cancer cells in peritoneal and pleural fluids compared to conventional cytology. Due to similar speciflcity and higher sensitivity, flow cytometry offers a promising alternative to cytology for patient screening.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Heping Tian, Genghuan Wang, Qi Zhong, Haihang Zhou
Summary: This study found that the decline of serum ITIH4 concentrations during the early phase after aneurysmal subarachnoid hemorrhage (aSAH) was closely related to the severity and poor prognosis of the disease. Serum ITIH4 may represent a promising prognostic biomarker of aSAH.
CLINICA CHIMICA ACTA
(2024)
Article
Medical Laboratory Technology
Xueting Zhu, Yang Yu, Jun Zhang, Yuxia Zhan, Guanghua Luo, Lu Zheng
Summary: This study successfully established a 2D-PCR method for identifying HLA-B*15:02 through a two-tube reaction. This method can distinguish HLA-B*15:02 from 16 highly homologous HLA-B*15 alleles. Among 1830 samples from the clinical general population, 3 HLA-B*15:02 homozygotes and 84 HLA-B*15:02 heterozygotes were detected.
CLINICA CHIMICA ACTA
(2024)
