Journal
CLIMACTERIC
Volume 17, Issue -, Pages 4-7Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/13697137.2014.953047
Keywords
BONE; ESTROGEN; OSTEOPOROSIS; OSTEOPENIA; ANTI-FRACTURE EFFICACY
Categories
Ask authors/readers for more resources
Estrogen therapy was considered first-line therapy for the prevention and treatment of postmenopausal osteoporosis in 1984. Evidence from a large, randomized clinical trial in 2002 proved the efficacy of estrogen in the prevention of all types of osteoporosis-related fractures. Ironically, estrogen was relegated to second-line therapy, based on perceived safety concerns. The historical background to these decisions is presented. It is argued that this decision is not a reasonable reflection of the available evidence, especially in comparison to other available drugs
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available