Journal
CLIMACTERIC
Volume 17, Issue 2, Pages 164-172Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/13697137.2013.828197
Keywords
CARDIOVASCULAR DISEASE; TEHRAN LIPID AND GLUCOSE STUDY; MENOPAUSE
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Funding
- National Council of Scientific Research of Islamic Republic of Iran
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Objectives To explore the cardiovascular risk attributable to menopausal status in a 9-year follow-up, population-based study. Method All middle-aged women who met our eligibility criteria were selected from the Tehran Lipid and Glucose Study cohort. Data were collected by face-to-face interviews, physical examination and biochemical assessments at 3-year intervals. The World Health Organization classification was used to define menopausal status. Cardiovascular events that occurred in the cohort were investigated by a panel of medical specialists. Results Based on menopausal status, there were no significant differences in cardiovascular disease after adjustment for age, body mass index and other confounders; however, significant relationships between serum concentrations of low density cholesterol and total cholesterol and menopausal status were observed. Conclusions Menopause, independent of other cardiovascular disease risk factors, incurred cardiometabolic risk.
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